ENgineered CArtilage from Nose for the Treatment of Osteoarthritis (ENCANTO)

Project Information

ENCANTO

Grant agreement ID: 101137315

DOI

10.3030/101137315

EC signature date 11 December 2023

Start date 1 January 2024

End date 31 December 2029

Funded under

• Health

Total cost

€ 8 363 555,00

EU contribution

€ 8 363 555,00

Coordinated by

FONDAZIONE POLICLINICO UNIVERSITARIO CAMPUS BIO MEDICO
Italy

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Definition and implementation of digital rehabilitation program and monitoring

Defined rehabilitation program with corresponding videos and detailed instructions in all languages implemented in the online platform. Digital monitoring and data acquisitionimplemented in the rehabilitation protocol on four levels: 1) ability to perform a specific task within dailyprotocol, 2) VAS pain score on daily basis, 3) traffic light system and 4)Bassett patient self-report scales for elapsed rehabilitation week.

Dissemination and Communication Plan first version

Dissemination and Communication plan report

Websites, patent fillings, videos etc. (1)

Project Website

The public website of the project.

Publications

Peer reviewed articles (4)

White paper – A proposal towards objective biomechanical metrics as novel endpoints to document improvements in musculoskeletal function and mobility

Author(s): Sónia A. Alves, Nicholas M. Brisson, Alison N. Agres, Mark Heyland, Ali Mobasheri, David J. Hunter, Tobias Winkler, Georg N. Duda
Published in: Osteoarthritis and Cartilage Open, Issue 7, 2025, ISSN 2665-9131
Publisher: Elsevier BV
DOI: 10.1016/J.OCARTO.2025.100648

Insights into chondrocyte populations in cartilaginous tissues at the single-cell level

Author(s): Csaba Matta, Roland Takács, Mona Dvir-Ginzberg, Stephen M. Richardson, Karoliina Pelttari, Girish Pattappa, Makarand V. Risbud, Ali Mobasheri
Published in: Nature Reviews Rheumatology, Issue 21, 2025, ISSN 1759-4790
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41584-025-01275-0

Gene therapy pipelines for osteoarthritis: current innovations, operational challenges, and future directions

Author(s): Valtteri Peitso, Karman Ng, Ron Ellis, Jean-Yves Reginster, Christopher H. Evans, Ali Mobasheri
Published in: Connective Tissue Research, 2025, ISSN 0300-8207
Publisher: Informa UK Limited
DOI: 10.1080/03008207.2025.2520319

Clinical relevance of engineered cartilage maturation in a randomized multicenter trial for articular cartilage repair

Author(s): Marcus Mumme, Anke Wixmerten, Alan Ivkovic, Giuseppe M. Peretti, Tayfun Yilmaz, Stephan Reppenhagen, Oliver Pullig, Sylvie Miot, Kaywan Izadpanah, Marcel Jakob, Laura Mangiavini, Corrado Sosio, Filip Vuletić, Oliver Bieri, Stefano Biguzzi, Brigitta Gahl, Gyözö Lehoczky, Rudolf Vukojevic, Sebastian Häusner, Anna Gryadunova, Martin Haug, Andrea Barbero, Ivan Martin
Published in: Science Translational Medicine, Issue 17, 2025, ISSN 1946-6234
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCITRANSLMED.ADS0848

Conference proceedings (1)

Early Osteoarthritic Lesions: A Therapeutic Dead-End or an Opportunity?

Author(s): Marcus Mumme
Published in: Annual Congress Swiss Orthopaedics Zurich, 2025
Publisher: N/A