ENgineered CArtilage from Nose for the Treatment of Osteoarthritis (ENCANTO)

Informacje na temat projektu

ENCANTO

Identyfikator umowy o grant: 101137315

DOI

10.3030/101137315

Data podpisania przez KE 11 Grudnia 2023

Data rozpoczęcia 1 Stycznia 2024

Data zakończenia 31 Grudnia 2029

Finansowanie w ramach

• Health

Koszt całkowity

€ 8 363 555,00

Wkład UE

€ 8 363 555,00

Koordynowany przez

FONDAZIONE POLICLINICO UNIVERSITARIO CAMPUS BIO MEDICO
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (2)

Definition and implementation of digital rehabilitation program and monitoring

Defined rehabilitation program with corresponding videos and detailed instructions in all languages implemented in the online platform. Digital monitoring and data acquisitionimplemented in the rehabilitation protocol on four levels: 1) ability to perform a specific task within dailyprotocol, 2) VAS pain score on daily basis, 3) traffic light system and 4)Bassett patient self-report scales for elapsed rehabilitation week.

Dissemination and Communication Plan first version

Dissemination and Communication plan report

Websites, patent fillings, videos etc. (1)

Project Website

The public website of the project.

Publikacje

Peer reviewed articles (14)

Looking Inwards: The Role of Self‐Care, Self‐Management and Self‐Healing in Musculoskeletal Pain

Autorzy: Joyce McSwan, Catherine E. Panwar, Ali Mobasheri
Opublikowane w: Musculoskeletal Care, Numer 23, 2025, ISSN 1478-2189
Wydawca: Wiley
DOI: 10.1002/MSC.70169

White paper – A proposal towards objective biomechanical metrics as novel endpoints to document improvements in musculoskeletal function and mobility

Autorzy: Sónia A. Alves, Nicholas M. Brisson, Alison N. Agres, Mark Heyland, Ali Mobasheri, David J. Hunter, Tobias Winkler, Georg N. Duda
Opublikowane w: Osteoarthritis and Cartilage Open, Numer 7, 2025, ISSN 2665-9131
Wydawca: Elsevier BV
DOI: 10.1016/J.OCARTO.2025.100648

Omics-driven insights into the molecular pathways driving osteoarthritis pathogenesis

Autorzy: Paco Mattheus Jacobus Welsing, Said el Bouhaddani, Lin Zhu, Nienke C. Nijhof, Simon C. Mastbergen, Chunyi Wen, Jaume Bacardit, Cristina Ruiz-Romero, Francisco J. Blanco, Ali Mobasheri
Opublikowane w: Connective Tissue Research, Numer 66, 2026, ISSN 0300-8207
Wydawca: Informa UK Limited
DOI: 10.1080/03008207.2025.2541291

White paper – A proposal towards objective biomechanical metrics as novel endpoints to document improvements in musculoskeletal function and mobility

Autorzy: Sónia A. Alves, Nicholas M. Brisson, Alison N. Agres, Mark Heyland, Ali Mobasheri, David J. Hunter, Tobias Winkler, Georg N. Duda
Opublikowane w: Osteoarthritis and Cartilage Open, Numer 7, 2025, ISSN 2665-9131
Wydawca: Elsevier BV
DOI: 10.1016/J.OCARTO.2025.100648

Bone health and pregnancy: Osteoporosis and beyond

Autorzy: Ali Mobasheri, Jean-Yves Reginster, Manju Chandran, Joyce McSwan
Opublikowane w: Case Reports in Women's Health, Numer 47, 2025, ISSN 2214-9112
Wydawca: Elsevier BV
DOI: 10.1016/J.CRWH.2025.E00725

Insights into chondrocyte populations in cartilaginous tissues at the single-cell level

Autorzy: Csaba Matta, Roland Takács, Mona Dvir-Ginzberg, Stephen M. Richardson, Karoliina Pelttari, Girish Pattappa, Makarand V. Risbud, Ali Mobasheri
Opublikowane w: Nature Reviews Rheumatology, Numer 21, 2025, ISSN 1759-4790
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/S41584-025-01275-0

Integrative spatially resolved proteomic and metabolomic imaging reveals synovitis endotypes implicated in osteoarthritis progression

Autorzy: Lin Zhu, Xin Diao, Chenrui Yuan, Chun Man Lawrence Lau, Jianing Wang, Wenlong Wu, Ali Mobasheri, Xavier Houard, Chunyi Wen, Zongwei Cai
Opublikowane w: Theranostics, Numer 15, 2025, ISSN 1838-7640
Wydawca: Ivyspring International Publisher
DOI: 10.7150/THNO.117788

Disruption of the microenvironmental ecosystem in subchondral bone marrow lesions: Roles in osteoarthritis pathophysiology, pain and progression

Autorzy: Ali Mobasheri, João Henriques, Jamie E. Collins
Opublikowane w: Osteoarthritis Imaging, Numer 6, 2026, ISSN 2772-6541
Wydawca: Elsevier BV
DOI: 10.1016/J.OSTIMA.2025.100374

Gene therapy pipelines for osteoarthritis: current innovations, operational challenges, and future directions

Autorzy: Valtteri Peitso, Karman Ng, Ron Ellis, Jean-Yves Reginster, Christopher H. Evans, Ali Mobasheri
Opublikowane w: Connective Tissue Research, 2025, ISSN 0300-8207
Wydawca: Informa UK Limited
DOI: 10.1080/03008207.2025.2520319

Clinical relevance of engineered cartilage maturation in a randomized multicenter trial for articular cartilage repair

Autorzy: Marcus Mumme, Anke Wixmerten, Alan Ivkovic, Giuseppe M. Peretti, Tayfun Yilmaz, Stephan Reppenhagen, Oliver Pullig, Sylvie Miot, Kaywan Izadpanah, Marcel Jakob, Laura Mangiavini, Corrado Sosio, Filip Vuletić, Oliver Bieri, Stefano Biguzzi, Brigitta Gahl, Gyözö Lehoczky, Rudolf Vukojevic, Sebastian Häusner, Anna Gryadunova, Martin Haug, Andrea Barbero, Ivan Martin
Opublikowane w: Science Translational Medicine, Numer 17, 2025, ISSN 1946-6234
Wydawca: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCITRANSLMED.ADS0848

Rapidly progressive osteoarthritis (RPOA) in companion animals treated with bedinvetmab (Librela™): an expected pathophysiological phenomenon or a cause for concern?

Autorzy: Ali Mobasheri, Peter Hanson, Jonathan Larkin
Opublikowane w: Frontiers in Veterinary Science, Numer 12, 2025, ISSN 2297-1769
Wydawca: Frontiers Media SA
DOI: 10.3389/FVETS.2025.1640217

Gene therapy pipelines for osteoarthritis: current innovations, operational challenges, and future directions

Autorzy: Valtteri Peitso, Karman Ng, Ron Ellis, Jean-Yves Reginster, Christopher H. Evans, Ali Mobasheri
Opublikowane w: Connective Tissue Research, Numer 66, 2026, ISSN 0300-8207
Wydawca: Informa UK Limited
DOI: 10.1080/03008207.2025.2520319

Next-generation therapies for osteoarthritis: the evolving role of cell therapy products

Autorzy: Valtteri Peitso, Ron Ellis, Karman Ng, Simone Ponta, Rana Smaida, Nadia Benkirane-Jessel, Nancy P. Duarte-Delgado, Tobias Winkler, Goncalo Barreto, Jean-Yves Reginster, Ali Mobasheri
Opublikowane w: Experimental & Molecular Medicine, Numer 58, 2026, ISSN 2092-6413
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/S12276-026-01726-Y

Emerging concepts in osteoarthritis and musculoskeletal diseases: Insights from the University of Debrecen Musculoskeletal Symposium 2025

Autorzy: Patrik Kovács, Judit Vágó, Ali Mobasheri, Zsuzsa Jenei-Lanzl, Frank Zaucke, Henning Madry, László Csernoch, Zoltán Szekanecz, Zsuzsa Szondy, Árpád Szöőr, Istvan Szatmari, Tamás Oláh, Csaba Matta
Opublikowane w: Osteoarthritis and Cartilage Open, Numer 8, 2026, ISSN 2665-9131
Wydawca: Elsevier BV
DOI: 10.1016/J.OCARTO.2025.100728

Conference proceedings (2)

Nose to knee. State of Art in clinical application of GMP products of nasal chondrocytes

Autorzy: Marcus Mumme
Opublikowane w: TERMIS EU 2025 Freiburg
Wydawca: N/A

Early Osteoarthritic Lesions: A Therapeutic Dead-End or an Opportunity?

Autorzy: Marcus Mumme
Opublikowane w: Annual Congress Swiss Orthopaedics Zurich, 2025
Wydawca: N/A