Novel Effect biomarkers for MEtabolic disruptorS: evidence on health Impacts to answer science and policy needS

Informations projet

NEMESIS

N° de convention de subvention: 101137405

DOI

10.3030/101137405

Date de signature de la CE 8 Decembre 2023

Date de début 1 Janvier 2024

Date de fin 31 Decembre 2028

Financé au titre de

• Health

Coût total

€ 7 965 638,75

Contribution de l’UE

€ 7 881 685,25

Coordonné par

ITA-SUOMEN YLIOPISTO
Finland

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (3)

Cluster policy strategy_1

Cluster policy strategy

Common cluster activities

Common cluster activities, including a common dissemination and communication strategy for the cluster

Cluster scientific strategy

Includes thematic workshops/trainings on issues of common interests. Planned workshops M24, M36, M48, M54

Websites, patent fillings, videos etc. (6)

Cluster newsletter_1

1st Cluster newsletter

NEMESIS Brochure

Leaflet on information for dissemination (events)

NEMESIS website

A project dedicated public website (continuously updated)

Cluster brochure
NEMESIS Initial press release

Initial press release describing the overall goals and ambition

Cluster web portal and visual identity

Data Management Plan (1)

Cluster data management plan

Common data management plans

Publications

Peer reviewed articles (10)

Diabetes mellitus and the key role of endoplasmic reticulum stress in pancreatic β cells

Auteurs: Maria Lytrivi, Yue Tong, Enrico Virgilio, Xiaoyan Yi, Miriam Cnop
Publié dans: Nature Reviews Endocrinology, 2025, ISSN 1759-5029
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41574-025-01129-5

Method optimization for a simultaneous determination of neonicotinoid, carbamate/thiocarbamate, triazole, organophosphate and pyrethroid pesticides and their metabolites in urine using UPLC-MS/MS

Auteurs: Carolina M. Bustamante, Natalia Bravo, Paula Ruiz, Joan O. Grimalt, Mercè Garí
Publié dans: Journal of Chromatography A, Numéro 1730, 2024, ISSN 0021-9673
Éditeur: Elsevier BV
DOI: 10.1016/j.chroma.2024.465054

Method optimization for a simultaneous determination of neonicotinoid, carbamate/thiocarbamate, triazole, organophosphate and pyrethroid pesticides and their metabolites in urine using UPLC-MS/MS

Auteurs: Bustamante, Carolina M.; Bravo, Natalia; Ruiz, Paula; Grimalt, Joan O.; Garí, Mercè
Publié dans: Journal of Chromatography A, 2024, ISSN 1873-3778
Éditeur: Elsevier
DOI: 10.1016/J.CHROMA.2024.465054

Metabolic disruption by mycotoxins: focus on metabolic endpoints steatosis, adipogenesis and glucose metabolism in vivo and in vitro

Auteurs: Tia Heikkinen, Jenni Küblbeck, Jaana Rysä
Publié dans: Archives of Toxicology, 2025, ISSN 0340-5761
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/S00204-025-03957-W

Association between phthalate exposure and metabolic dysfunction-associated steatotic liver disease (MASLD) – Systematic literature review

Auteurs: Tomasz Gogola, Sini Pitkänen, Marjo Huovinen, Heikki Laitinen, Jenni Küblbeck
Publié dans: Environmental Research, Numéro 273, 2025, ISSN 0013-9351
Éditeur: Elsevier BV
DOI: 10.1016/J.ENVRES.2025.121186

Unmasking metabolic disruptors: The NEMESIS project's quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies

Auteurs: Henriikka Hakomäki; Sini Pitkänen; Anna-Liisa Levonen; Paavo Honkakoski; Dario Greco; Laura Aliisa Saarimäki; Susana Viegas; Cristina Godinho; Nanna Fyhrquist; Emma Wincent; Volker M Lauschke; Janne Hukkanen; Jukka Hakkola; Ludovic Vallier; Vittorio Fortino; Antreas Afantitis; Toshiaki Sawatani; Tereso J Guzman; Miriam Cnop; Tim Nawrot; Sophia Harlid; Marie-Therese Vinnars; Adonina Tardon; Joan O Grimalt; Jenni Küblbeck; Jaana Rysä
Publié dans: Open Research Europe, 2024, ISSN 2732-5121
Éditeur: European Commission
DOI: 10.12688/OPENRESEUROPE.18439.1

Chemical disruption of placental thyroid hormone signalling: a systematic review that highlights sex-specific effects

Auteurs: Julia Swan, D. Zhurenko, K. M. Huttunen, J. Rysä
Publié dans: Archives of Toxicology, 2025, ISSN 0340-5761
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/S00204-025-04203-Z

Methodological approach for a simultaneous determination of persistent and non-persistent organic pollutants in human blood (serum/plasma) using gas chromatography and mass spectrometry techniques

Auteurs: Carolina M. Bustamante; Paula Ruiz; Atiya B. Rifat; Natalia Bravo; Joan O. Grimalt; Mercè Garí
Publié dans: Journal of Chromatography A, 2025, ISSN 1873-3778
Éditeur: Elsevier
DOI: 10.1016/J.CHROMA.2025.466235

A Systematic Literature Review of Reproductive Toxicological Studies on Phthalates

Auteurs: Muhammad Moghazy, Marianthi Papathanasiou, Haralampos Tzoupis, Konstantinos D. Papavasileiou, Chen Xing, Volker M. Lauschke, Antreas Afantitis, Georgia Melagraki
Publié dans: International Journal of Molecular Sciences, Numéro 26, 2025, ISSN 1422-0067
Éditeur: MDPI AG
DOI: 10.3390/IJMS26188761

Nuclear receptors CAR and PXR as cardiometabolic regulators

Auteurs: Janne Hukkanen, Jenni Küblbeck, Jukka Hakkola, Jaana Rysä
Publié dans: Pharmacological Research, Numéro 219, 2025, ISSN 1043-6618
Éditeur: Elsevier BV
DOI: 10.1016/J.PHRS.2025.107892