Novel Effect biomarkers for MEtabolic disruptorS: evidence on health Impacts to answer science and policy needS

Projektinformationen

NEMESIS

ID Finanzhilfevereinbarung: 101137405

DOI

10.3030/101137405

EK-Unterschriftsdatum 8 Dezember 2023

Startdatum 1 Januar 2024

Enddatum 31 Dezember 2028

Finanziert unter

• Health

Gesamtkosten

€ 7 965 638,75

EU-Beitrag

€ 7 881 685,25

Koordiniert durch

ITA-SUOMEN YLIOPISTO
Finland

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (6)

NEMESIS D&C plan

Detailed project dissemination and communication plan (living document)

A map of EDC mixture effects on liver toxicity

Report on combinatorial effects of EDCs in human liver toxicity

Cluster policy strategy_1

Cluster policy strategy

Common cluster activities

Common cluster activities, including a common dissemination and communication strategy for the cluster

Cluster scientific strategy

Includes thematic workshops/trainings on issues of common interests. Planned workshops M24, M36, M48, M54

Map of available methodologies for RA of EDCs

Report summarizing available methodologies in different RA frameworks for EDCs

Websites, patent fillings, videos etc. (6)

Cluster newsletter_1

1st Cluster newsletter

NEMESIS Brochure

Leaflet on information for dissemination (events)

NEMESIS website

A project dedicated public website (continuously updated)

Cluster brochure
NEMESIS Initial press release

Initial press release describing the overall goals and ambition

Cluster web portal and visual identity

Data Management Plan (3)

FAIR research data management plan (RDMP)_1

Procedures for collecting, organizing, storing, and sharing research data - initial version

Cluster data management plan

Common data management plans

FAIR research data management plan (RDMP)_2

Procedures for collecting, organizing, storing, and sharing research data - full version

Veröffentlichungen

Peer reviewed articles (10)

Diabetes mellitus and the key role of endoplasmic reticulum stress in pancreatic β cells

Autoren: Maria Lytrivi, Yue Tong, Enrico Virgilio, Xiaoyan Yi, Miriam Cnop
Veröffentlicht in: Nature Reviews Endocrinology, 2025, ISSN 1759-5029
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/S41574-025-01129-5

Method optimization for a simultaneous determination of neonicotinoid, carbamate/thiocarbamate, triazole, organophosphate and pyrethroid pesticides and their metabolites in urine using UPLC-MS/MS

Autoren: Carolina M. Bustamante, Natalia Bravo, Paula Ruiz, Joan O. Grimalt, Mercè Garí
Veröffentlicht in: Journal of Chromatography A, Ausgabe 1730, 2024, ISSN 0021-9673
Herausgeber: Elsevier BV
DOI: 10.1016/j.chroma.2024.465054

Method optimization for a simultaneous determination of neonicotinoid, carbamate/thiocarbamate, triazole, organophosphate and pyrethroid pesticides and their metabolites in urine using UPLC-MS/MS

Autoren: Bustamante, Carolina M.; Bravo, Natalia; Ruiz, Paula; Grimalt, Joan O.; Garí, Mercè
Veröffentlicht in: Journal of Chromatography A, 2024, ISSN 1873-3778
Herausgeber: Elsevier
DOI: 10.1016/J.CHROMA.2024.465054

Metabolic disruption by mycotoxins: focus on metabolic endpoints steatosis, adipogenesis and glucose metabolism in vivo and in vitro

Autoren: Tia Heikkinen, Jenni Küblbeck, Jaana Rysä
Veröffentlicht in: Archives of Toxicology, 2025, ISSN 0340-5761
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1007/S00204-025-03957-W

Association between phthalate exposure and metabolic dysfunction-associated steatotic liver disease (MASLD) – Systematic literature review

Autoren: Tomasz Gogola, Sini Pitkänen, Marjo Huovinen, Heikki Laitinen, Jenni Küblbeck
Veröffentlicht in: Environmental Research, Ausgabe 273, 2025, ISSN 0013-9351
Herausgeber: Elsevier BV
DOI: 10.1016/J.ENVRES.2025.121186

Unmasking metabolic disruptors: The NEMESIS project's quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies

Autoren: Henriikka Hakomäki; Sini Pitkänen; Anna-Liisa Levonen; Paavo Honkakoski; Dario Greco; Laura Aliisa Saarimäki; Susana Viegas; Cristina Godinho; Nanna Fyhrquist; Emma Wincent; Volker M Lauschke; Janne Hukkanen; Jukka Hakkola; Ludovic Vallier; Vittorio Fortino; Antreas Afantitis; Toshiaki Sawatani; Tereso J Guzman; Miriam Cnop; Tim Nawrot; Sophia Harlid; Marie-Therese Vinnars; Adonina Tardon; Joan O Grimalt; Jenni Küblbeck; Jaana Rysä
Veröffentlicht in: Open Research Europe, 2024, ISSN 2732-5121
Herausgeber: European Commission
DOI: 10.12688/OPENRESEUROPE.18439.1

Chemical disruption of placental thyroid hormone signalling: a systematic review that highlights sex-specific effects

Autoren: Julia Swan, D. Zhurenko, K. M. Huttunen, J. Rysä
Veröffentlicht in: Archives of Toxicology, 2025, ISSN 0340-5761
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1007/S00204-025-04203-Z

Methodological approach for a simultaneous determination of persistent and non-persistent organic pollutants in human blood (serum/plasma) using gas chromatography and mass spectrometry techniques

Autoren: Carolina M. Bustamante; Paula Ruiz; Atiya B. Rifat; Natalia Bravo; Joan O. Grimalt; Mercè Garí
Veröffentlicht in: Journal of Chromatography A, 2025, ISSN 1873-3778
Herausgeber: Elsevier
DOI: 10.1016/J.CHROMA.2025.466235

A Systematic Literature Review of Reproductive Toxicological Studies on Phthalates

Autoren: Muhammad Moghazy, Marianthi Papathanasiou, Haralampos Tzoupis, Konstantinos D. Papavasileiou, Chen Xing, Volker M. Lauschke, Antreas Afantitis, Georgia Melagraki
Veröffentlicht in: International Journal of Molecular Sciences, Ausgabe 26, 2025, ISSN 1422-0067
Herausgeber: MDPI AG
DOI: 10.3390/IJMS26188761

Nuclear receptors CAR and PXR as cardiometabolic regulators

Autoren: Janne Hukkanen, Jenni Küblbeck, Jukka Hakkola, Jaana Rysä
Veröffentlicht in: Pharmacological Research, Ausgabe 219, 2025, ISSN 1043-6618
Herausgeber: Elsevier BV
DOI: 10.1016/J.PHRS.2025.107892