The work carried out in the M1 to M18 period has progressed very well and has centred on the following technical WP activities. Within WP1 the first foundations for a data ecosystem aligned with FAIR principles has been established. It includes a data management plan, integration with external databases, and a user-friendly interface to support SSbD workflows. This task compiles basic data on physical and chemical properties of the pristine material and incorporated in material selected for the project.
The demand on data is first defined by WP2. As physico-chemical properties of SSbD4CheM materials are required as input for the SSbD assessment with predictive material developed (WP2, 5, 6 ,7) within WP3 data template for physico-chemical characterisation of SSbD4CheM (nano-)materials using existing analytical methodologies has been established as an input to WP1, on another new methodologies to close gaps in physico-chemical characterisation and exposure of materials has been started including non-target analysis of materials using mass spectrometry (VOC emissions) and data evaluation schemes, field-flow fractionation with emphasis on light scattering detection to characterise (nano-)particles with high aspect ratios, as well as Imaging based on Focused Ion Beam Secondary Ion Mass Spectrometry (FIB-SIMS) for high resolution physico-chemical analysis to characterise materials.
WP4 on another side conducted substantional work on the development of a suite of innovative complex models of the major tissue barriers that protect human health, placing them in a systems toxicology context. First results on the skin, lung and gut barriers were addressed together with the alternative model zebrafish embryo.
WP5 is focusing on the potential risk and exposure pathways for occupational, consumer, and environmental setting, as well as on the fate and behaviour of emitted particles/chemicals in the environment.
WP6 main goal is to improve and develop an innovative methodology to assess ex-ante LCA and testing it towards automotive case study. Once when the method is clearly established it will be further implemented in other two case studies.
WP7 acts as a case study implementation wprk package in order to give a prototyping and validation of composites, coatings and nanocellulose according to use case requirements (automotive, textile, cosmetics) with fulfilled sustainability and safety aspects.
Lastly, WP8 is expanding the project’s visibility and community engagement, introducing a cohesive brand identity and website, building a strong presence across social media, and driving stakeholder involvement through workshops and networking events.
