Platelet-derived integrin- and tetraspanin-enriched tethers exacerbate severe inflammation
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Autori:
Charly Kusch, David Stegner, Lukas J. Weiss, Paquita Nurden, Philipp Burkard, Denise Johnson, Wolfgang Bergmeier, Ceylan Onursal, Stefano Navarro, Christian Hackenbroch, Dennis Pfeiffer, Sabrina Ivana Bonfiglio, Mara Meub, Carina Gross, Joachim Schenk, Valeria Fumagalli, Kristina Mott, Markus Bender, Matteo Iannacone, Oliver Andres, Wolfgang Kastenmüller, Katrin G. Heinze, Markus Sauer, Harald Schulze, Klaus Ley, Alan T. Nurden, Bernhard Nieswandt
Pubblicato in:
Science, Numero 391, 2026, ISSN 0036-8075
Editore:
American Association for the Advancement of Science (AAAS)
DOI:
10.1126/SCIENCE.ADU2825
Partial downregulation of platelet glycoprotein VI by low affinity antibodies confers sustained and safe antithrombotic protection
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Autori:
Stefano Navarro, Sarah Beck, Sabrina I. Bonfiglio, Ernesto J. Cuenca-Zamora, Lukas J. Weiß, Marijke Kuijpers, Johan Heemskerk, David Stegner, Bernhard Nieswandt
Pubblicato in:
Signal Transduction and Targeted Therapy, Numero 11, 2026, ISSN 2059-3635
Editore:
Springer Science and Business Media LLC
DOI:
10.1038/S41392-026-02864-5
