Glycosylation strategy in bio-hybrid Light Emitting diodEs

Projektinformationen

GLEE

ID Finanzhilfevereinbarung: 101150842

DOI

10.3030/101150842

Das Projekt endete am 31 Oktober 2024

EK-Unterschriftsdatum 15 März 2024

Startdatum 1 Juli 2024

Enddatum 30 Juni 2026

Finanziert unter

• Marie Skłodowska-Curie Actions (MSCA)

Gesamtkosten

Keine Daten

EU-Beitrag

€ 173 847,36

Koordiniert durch

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

Periodic Reporting for period 1 - GLEE (Glycosylation strategy in bio-hybrid Light Emitting diodEs)

Berichtszeitraum: 2024-07-01 bis 2026-06-30

Zusammenfassung vom Kontext und den Gesamtzielen des Projekts

Explanation of the work carried out by the beneficiaries and overview of the progress

Objectives:

The project has achieved all the objectives and milestones for this period. In fact, some additional experiments for sections that were originally planned for later months were performed obtaining promising results that will be explained below.


The goals of this project were:

1) To performed a glyco-protection to enhance FP stability by new synthetic protocols of first glyco-artificial FPs and glyco-polymeric matrices.

2) To set relationships between sugar modification and thermal-/photo- stability to design the best glyco-shell/ends for lighting devices.

3) Next generation of highly stable and efficient high-power on-chip BioHLEDs.

Arbeit, die ab Beginn des Projekts bis zum Ende des durch den Bericht erfassten Berichtszeitraums geleistet wurde, und die wichtigsten bis dahin erzielten Ergebnisse

Work Package 2: Exploitation/Dissemination/Communication

Open Access publishing of GLEE’s outputs:

2 papers on process to be published in Open Access journals.

1. Glycosylated Polymers Toward Stable Protein-based Lighting. Macromolecular Chemistry
and Physics (Wiley): accepted in 10.12.2024 and will be published soon with the DOI:
10.1002/macp.202400429. The paper has been licensed as gold open access. This is related
to the activities described in WP3 (T.3.1.2; T3.2.) and WP4 (T4.1)
2. Sweeting the deal in protein-based lighting. Tentative submission to Advanced Materials
(Wiley). This is related to the activities described in WP3 (T.3.1.1; T3.2) and WP4 (T4.1)

Workpackage 3: Synthesis and Characterization of GAFPs and GPMs:

T3.1 Synthesis of GAFPs/GPMs (from M1):

As previously mentioned in Section 1.1 the tasks of this work package were almost totally
achieved. A family of new GAFPs and GPMs have been successfully synthesized.

Workpackage 4:Fabrication and Analasys of BIO-HLEDs with GAFPs/GPMs

T4.1 Monochromatic BioHLEDs with optimized GAFP-GPM coatings (from M10)
Although this task was scheduled to begin in M10, we have already initiated the fabrication and
analysis of Bio-HLEDs with the first GAFP and GFP polymer coatings.

Fortschritte, die über den aktuellen Stand der Technik hinausgehen und voraussichtliche potenzielle Auswirkungen (einschließlich der bis dato erzielten sozioökonomischen Auswirkungen und weiter gefassten gesellschaftlichen Auswirkungen des Projekts)

Monochromatic BioHLEDs with optimized GAFP-GPM coatings resulted in 300 times stability enhancement. However, the device stability is far below the standards for commerciation in LEDs. Thus, the exploitation strategy was not proceeded. As next steps, the compatibility with other polymer coatings should be tested.
Likewise, the device with glyco-FP did not result in a strong enhancement of the device stability that could granted a patent application. Indeed, this should tested with other FP to determine if this approach could be universial.

protecting FP with sugars polymers