Glycosylation strategy in bio-hybrid Light Emitting diodEs

Informazioni relative al progetto

GLEE

ID dell’accordo di sovvenzione: 101150842

DOI

10.3030/101150842

Progetto concluso il 31 Ottobre 2024

Data della firma CE 15 Marzo 2024

Data di avvio 1 Luglio 2024

Data di completamento 30 Giugno 2026

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 173 847,36

Coordinato da

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

Periodic Reporting for period 1 - GLEE (Glycosylation strategy in bio-hybrid Light Emitting diodEs)

Periodo di rendicontazione: 2024-07-01 al 2026-06-30

Sintesi del contesto e degli obiettivi generali del progetto

Explanation of the work carried out by the beneficiaries and overview of the progress

Objectives:

The project has achieved all the objectives and milestones for this period. In fact, some additional experiments for sections that were originally planned for later months were performed obtaining promising results that will be explained below.


The goals of this project were:

1) To performed a glyco-protection to enhance FP stability by new synthetic protocols of first glyco-artificial FPs and glyco-polymeric matrices.

2) To set relationships between sugar modification and thermal-/photo- stability to design the best glyco-shell/ends for lighting devices.

3) Next generation of highly stable and efficient high-power on-chip BioHLEDs.

Lavoro eseguito dall’inizio del progetto fino alla fine del periodo coperto dalla relazione e principali risultati finora ottenuti

Work Package 2: Exploitation/Dissemination/Communication

Open Access publishing of GLEE’s outputs:

2 papers on process to be published in Open Access journals.

1. Glycosylated Polymers Toward Stable Protein-based Lighting. Macromolecular Chemistry
and Physics (Wiley): accepted in 10.12.2024 and will be published soon with the DOI:
10.1002/macp.202400429. The paper has been licensed as gold open access. This is related
to the activities described in WP3 (T.3.1.2; T3.2.) and WP4 (T4.1)
2. Sweeting the deal in protein-based lighting. Tentative submission to Advanced Materials
(Wiley). This is related to the activities described in WP3 (T.3.1.1; T3.2) and WP4 (T4.1)

Workpackage 3: Synthesis and Characterization of GAFPs and GPMs:

T3.1 Synthesis of GAFPs/GPMs (from M1):

As previously mentioned in Section 1.1 the tasks of this work package were almost totally
achieved. A family of new GAFPs and GPMs have been successfully synthesized.

Workpackage 4:Fabrication and Analasys of BIO-HLEDs with GAFPs/GPMs

T4.1 Monochromatic BioHLEDs with optimized GAFP-GPM coatings (from M10)
Although this task was scheduled to begin in M10, we have already initiated the fabrication and
analysis of Bio-HLEDs with the first GAFP and GFP polymer coatings.

Progressi oltre lo stato dell’arte e potenziale impatto previsto (incluso l’impatto socioeconomico e le implicazioni sociali più ampie del progetto fino ad ora)

Monochromatic BioHLEDs with optimized GAFP-GPM coatings resulted in 300 times stability enhancement. However, the device stability is far below the standards for commerciation in LEDs. Thus, the exploitation strategy was not proceeded. As next steps, the compatibility with other polymer coatings should be tested.
Likewise, the device with glyco-FP did not result in a strong enhancement of the device stability that could granted a patent application. Indeed, this should tested with other FP to determine if this approach could be universial.

protecting FP with sugars polymers