Boosting Sustainable Innovation in Developing New Antibiotic Adjuvants to Control Biofilm Resistance

Project Information

InnovAntiBiofilm

Grant agreement ID: 101157363

DOI

10.3030/101157363

EC signature date 10 May 2024

Start date 1 October 2024

End date 30 September 2027

Funded under

• Widening participation and spreading excellence

Total cost

No data

EU contribution

€ 1 483 246,42

Coordinated by

UNIVERSIDADE DO PORTO
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (18)

Science of the Total Environment

Author(s): Afonso, Ana C.; Botting, Jack; Gomes, Inês B.; Saavedra, Maria J.; Simões, Lúcia Chaves; Liu, Jun; Simões, Manuel
Published in: Science of The Total Environment, 2024, ISSN 0048-9697
Publisher: Elsevier
DOI: 10.1016/J.SCITOTENV.2024.174872

Protocol for in silico characterization of natural-based molecules as quorum-sensing inhibitors

Author(s): Susana Fernandes; Mariana Sousa; Fábio G. Martins; Manuel Simões; Sérgio F. Sousa
Published in: STAR Protocols, Issue 5, 2024, ISSN 2666-1667
Publisher: Cell Press
DOI: 10.1016/J.XPRO.2024.103367

Two cinnamic acid derivatives as inhibitors of Pseudomonas aeruginosa las and pqs quorum-sensing systems: Impact on biofilm formation and virulence factors

Author(s): Miguel M. Leitão, Ariana S.C. Gonçalves, Sérgio F. Sousa, Fernanda Borges, Manuel Simões, Anabela Borges
Published in: Biomedicine & Pharmacotherapy, Issue 187, 2025, ISSN 0753-3322
Publisher: Elsevier BV
DOI: 10.1016/J.BIOPHA.2025.118090

Unravelling the potential of natural chelating agents in the control of Staphylococcus aureus and Pseudomonas aeruginosa biofilms

Author(s): Miguel M. Leitão, Ariana S.C. Gonçalves, Joana Moreira, Carlos Fernandes, Fernanda Borges, Manuel Simões, Anabela Borges
Published in: European Journal of Medicinal Chemistry, Issue 283, 2025, ISSN 0223-5234
Publisher: Elsevier BV
DOI: 10.1016/J.EJMECH.2024.117163

The action of selected monoterpenes as biofilm control agents and antibiotic resistance modifiers

Author(s): Francisca Massano, Ana C. Afonso, Mariana Sousa, Lília S. Teixeira, Anabela Borges, Manuel Simões
Published in: Biofouling, 2026, ISSN 0892-7014
Publisher: Taylor & Francis
DOI: 10.1080/08927014.2026.2615081

The role of the proteosurfaceome and exoproteome in bacterial coaggregation

Author(s): Ana C. Afonso, Maria J. Saavedra, Manuel Simões, Lúcia C. Simões
Published in: Biotechnology Advances, Issue 79, 2025, ISSN 0734-9750
Publisher: Elsevier BV
DOI: 10.1016/J.BIOTECHADV.2024.108505

Elucidating bacterial coaggregation through a physicochemical and imaging surface characterization

Author(s): Ana C. Afonso, Jack Botting, Inês B. Gomes, Maria J. Saavedra, Lúcia C. Simões, Jun Liu, Manuel Simões
Published in: Science of The Total Environment, Issue 948, 2025, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/J.SCITOTENV.2024.174872

New insights on antibacterial mode of action of blue-light photoactivated berberine and curcumin-antibiotic combinations against Staphylococcus aureus

Author(s): Ariana S.C. Gonçalves, José R. Fernandes, Maria José Saavedra, Nuno M. Guimarães, Cristiana Pereira, Manuel Simões, Anabela Borges
Published in: Photodiagnosis and Photodynamic Therapy, Issue 52, 2025, ISSN 1572-1000
Publisher: Elsevier BV
DOI: 10.1016/J.PDPDT.2025.104514

Antimicrobial cyclodextrin-assisted electrospun fibers loaded with carvacrol, citronellol and cinnamic acid for wound healing

Author(s): Iago Gonzalez-Prada, Anabela Borges, Beatriz Santos-Torres, Beatriz Magariños, Manuel Simões, Angel Concheiro, Carmen Alvarez-Lorenzo
Published in: International Journal of Biological Macromolecules, Issue 277, 2024, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2024.134154

Coaggregation dynamics in drinking water biofilms and implications for chlorine disinfection

Author(s): Ana C. Afonso, Inês B. Gomes, Francisca Massano, Maria J. Saavedra, Manuel Simões, Lúcia C. Simões
Published in: Journal of Hazardous Materials, Issue 480, 2025, ISSN 0304-3894
Publisher: Elsevier BV
DOI: 10.1016/J.JHAZMAT.2024.135948

Photodynamic activation of phytochemical-antibiotic combinations for combatting Staphylococcus aureus from acute wound infections

Author(s): Ariana S.C. Gonçalves, Miguel M. Leitão, José R. Fernandes, Maria José Saavedra, Cristiana Pereira, Manuel Simões, Anabela Borges
Published in: Journal of Photochemistry and Photobiology B: Biology, Issue 258, 2024, ISSN 1011-1344
Publisher: Elsevier BV
DOI: 10.1016/J.JPHOTOBIOL.2024.112978

Polypharmacological strategies for infectious bacteria

Author(s): Miguel M. Leitão, Ariana S.C. Gonçalves, Fernanda Borges, Manuel Simões, Anabela Borges
Published in: Pharmacological Reviews, Issue 77, 2025, ISSN 0031-6997
Publisher: Elsevier BV
DOI: 10.1016/J.PHARMR.2025.100038

Biocides as drivers of antibiotic resistance: A critical review of environmental implications and public health risks

Author(s): Mariana Sousa, Idalina Machado, Lúcia C. Simões, Manuel Simões
Published in: Environmental Science and Ecotechnology, Issue 25, 2025, ISSN 2666-4984
Publisher: Elsevier BV
DOI: 10.1016/J.ESE.2025.100557

Current microbiological challenges in drinking water

Author(s): Ana C. Afonso, Maria J. Saavedra, Inês B. Gomes, Manuel Simões, Lúcia C. Simões
Published in: Journal of Water Process Engineering, Issue 72, 2025, ISSN 2214-7144
Publisher: Elsevier BV
DOI: 10.1016/J.JWPE.2025.107614

AHL-based QS signalling promotes uropathogenic Escherichia coli settlement through the de-repression of biofilm formation by SdiA

Author(s): Celia Mayer, Fadi Soukarieh, Manuel Simões, Saskia-Camille Flament-Simon, Miguel Cámara, Manuel Romero
Published in: PLOS One, Issue 20, 2025, ISSN 1932-6203
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PONE.0328837

The impact of methylparaben and chlorine on the architecture of Stenotrophomonas maltophilia biofilms

Author(s): Ana Rita Pereira, Liam M. Rooney, Inês B. Gomes, Manuel Simões, Gail McConnell
Published in: Science of The Total Environment, Issue 951, 2024, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/J.SCITOTENV.2024.175646

Dual action of benzaldehydes: Inhibiting quorum sensing and enhancing antibiotic efficacy for controlling Pseudomonas aeruginosa biofilms

Author(s): Miguel M. Leitão, Tatiana F. Vieira, Sérgio F. Sousa, Fernanda Borges, Manuel Simões, Anabela Borges
Published in: Microbial Pathogenesis, Issue 191, 2024, ISSN 0882-4010
Publisher: Elsevier BV
DOI: 10.1016/J.MICPATH.2024.106663

Exploring grape pomace extracts for the formulation of new bioactive multifunctional chitosan/alginate-based hydrogels for wound healing applications

Author(s): Lília S. Teixeira, Mariana Sousa, Francisca Massano, Anabela Borges
Published in: Food Bioscience, Issue 62, 2025, ISSN 2212-4292
Publisher: Elsevier BV
DOI: 10.1016/J.FBIO.2024.105073

Other (3)

COMMUNICATION, DISSEMINATION AND EXPLOITATION PLAN FOR THE INNOVANTIBIOFILM PROJECT

Author(s): Simões, Manuel; Borges, Anabela; Gomes, Inês
Published in: ZENODO, 2024
DOI: 10.5281/ZENODO.14753656

GUIDELINES FOR STAFF EXCHANGE OF THE INNOVANTIBIOFILM PROJECT

Author(s): Simões, Manuel; Oliveira Afonso, Ana Cristina; Gomes, Inês; Borges, Anabela
Published in: ZENODO, 2025
DOI: 10.5281/ZENODO.15280872

DATA MANAGEMENT PLAN FOR THE INNOVANTIBIOFILM PROJECT

Author(s): Simões, Manuel; Oliveira Afonso, Ana Cristina; Gomes, Inês; Borges, Anabela
Published in: ZENODO, 2025
DOI: 10.5281/ZENODO.15280816