Boosting Sustainable Innovation in Developing New Antibiotic Adjuvants to Control Biofilm Resistance

Informacje na temat projektu

InnovAntiBiofilm

Identyfikator umowy o grant: 101157363

DOI

10.3030/101157363

Data podpisania przez KE 10 Maja 2024

Data rozpoczęcia 1 Października 2024

Data zakończenia 30 Września 2027

Finansowanie w ramach

• Widening participation and spreading excellence

Koszt całkowity

Brak danych

Wkład UE

€ 1 483 246,42

Koordynowany przez

UNIVERSIDADE DO PORTO
Portugal

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (3)

Communication, Dissemination and Exploitation Plan

A detailed Communication, Dissemination and Exploitation Plan (CDEP) will be produced. The CDEP will outline the audiences, key messages and communication channels for dissemination. The CDEP will provide an integrated, inclusive, accurate and efficient communication, dissemination and exploitation strategy to fully promote the benefits of InnovAntiBiofilm and it will include a calendar of events (both internal and external) and a (first) list of stakeholders and end-users with a view to engage the most relevant actors.

Methods for Shikimic Acid Isolation and Purification

The isolation and purification of shikimic acid will include fermentation liquid pre-treatment. Shikimic acid will be purified by preparative HPLC/MS.

Catalogue of Industrial Stakeholders

UPORTO, CEA and Fraunhofer IME will contribute with their contacts and networks for an industrial stakeholder list that will be produced by KPMG.

Data Management Plan (1)

Data Management Plan

A Data Management Plan will be developed and periodically updated during the lifetime of the project (living document), tackling issues related to data privacy, security, visibility of internal business, trust, regulatory frameworks, use of personal data, business sensitive data, and data protection standards as established by the EU General Data Protection Regulation rules.

Publikacje

Peer reviewed articles (20)

Science of the Total Environment

Autorzy: Afonso, Ana C.; Botting, Jack; Gomes, Inês B.; Saavedra, Maria J.; Simões, Lúcia Chaves; Liu, Jun; Simões, Manuel
Opublikowane w: Science of The Total Environment, 2024, ISSN 0048-9697
Wydawca: Elsevier
DOI: 10.1016/J.SCITOTENV.2024.174872

Protocol for in silico characterization of natural-based molecules as quorum-sensing inhibitors

Autorzy: Susana Fernandes; Mariana Sousa; Fábio G. Martins; Manuel Simões; Sérgio F. Sousa
Opublikowane w: STAR Protocols, Numer 5, 2024, ISSN 2666-1667
Wydawca: Cell Press
DOI: 10.1016/J.XPRO.2024.103367

Two cinnamic acid derivatives as inhibitors of Pseudomonas aeruginosa las and pqs quorum-sensing systems: Impact on biofilm formation and virulence factors

Autorzy: Miguel M. Leitão, Ariana S.C. Gonçalves, Sérgio F. Sousa, Fernanda Borges, Manuel Simões, Anabela Borges
Opublikowane w: Biomedicine & Pharmacotherapy, Numer 187, 2025, ISSN 0753-3322
Wydawca: Elsevier BV
DOI: 10.1016/J.BIOPHA.2025.118090

Unravelling the potential of natural chelating agents in the control of Staphylococcus aureus and Pseudomonas aeruginosa biofilms

Autorzy: Miguel M. Leitão, Ariana S.C. Gonçalves, Joana Moreira, Carlos Fernandes, Fernanda Borges, Manuel Simões, Anabela Borges
Opublikowane w: European Journal of Medicinal Chemistry, Numer 283, 2025, ISSN 0223-5234
Wydawca: Elsevier BV
DOI: 10.1016/J.EJMECH.2024.117163

The action of selected monoterpenes as biofilm control agents and antibiotic resistance modifiers

Autorzy: Francisca Massano, Ana C. Afonso, Mariana Sousa, Lília S. Teixeira, Anabela Borges, Manuel Simões
Opublikowane w: Biofouling, 2026, ISSN 0892-7014
Wydawca: Taylor & Francis
DOI: 10.1080/08927014.2026.2615081

The role of the proteosurfaceome and exoproteome in bacterial coaggregation

Autorzy: Ana C. Afonso, Maria J. Saavedra, Manuel Simões, Lúcia C. Simões
Opublikowane w: Biotechnology Advances, Numer 79, 2025, ISSN 0734-9750
Wydawca: Elsevier BV
DOI: 10.1016/J.BIOTECHADV.2024.108505

Elucidating bacterial coaggregation through a physicochemical and imaging surface characterization

Autorzy: Ana C. Afonso, Jack Botting, Inês B. Gomes, Maria J. Saavedra, Lúcia C. Simões, Jun Liu, Manuel Simões
Opublikowane w: Science of The Total Environment, Numer 948, 2025, ISSN 0048-9697
Wydawca: Elsevier BV
DOI: 10.1016/J.SCITOTENV.2024.174872

New insights on antibacterial mode of action of blue-light photoactivated berberine and curcumin-antibiotic combinations against Staphylococcus aureus

Autorzy: Ariana S.C. Gonçalves, José R. Fernandes, Maria José Saavedra, Nuno M. Guimarães, Cristiana Pereira, Manuel Simões, Anabela Borges
Opublikowane w: Photodiagnosis and Photodynamic Therapy, Numer 52, 2025, ISSN 1572-1000
Wydawca: Elsevier BV
DOI: 10.1016/J.PDPDT.2025.104514

Antimicrobial cyclodextrin-assisted electrospun fibers loaded with carvacrol, citronellol and cinnamic acid for wound healing

Autorzy: Iago Gonzalez-Prada, Anabela Borges, Beatriz Santos-Torres, Beatriz Magariños, Manuel Simões, Angel Concheiro, Carmen Alvarez-Lorenzo
Opublikowane w: International Journal of Biological Macromolecules, Numer 277, 2024, ISSN 0141-8130
Wydawca: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2024.134154

Coaggregation dynamics in drinking water biofilms and implications for chlorine disinfection

Autorzy: Ana C. Afonso, Inês B. Gomes, Francisca Massano, Maria J. Saavedra, Manuel Simões, Lúcia C. Simões
Opublikowane w: Journal of Hazardous Materials, Numer 480, 2025, ISSN 0304-3894
Wydawca: Elsevier BV
DOI: 10.1016/J.JHAZMAT.2024.135948

Photodynamic activation of phytochemical-antibiotic combinations for combatting Staphylococcus aureus from acute wound infections

Autorzy: Ariana S.C. Gonçalves, Miguel M. Leitão, José R. Fernandes, Maria José Saavedra, Cristiana Pereira, Manuel Simões, Anabela Borges
Opublikowane w: Journal of Photochemistry and Photobiology B: Biology, Numer 258, 2024, ISSN 1011-1344
Wydawca: Elsevier BV
DOI: 10.1016/J.JPHOTOBIOL.2024.112978

Polypharmacological strategies for infectious bacteria

Autorzy: Miguel M. Leitão, Ariana S.C. Gonçalves, Fernanda Borges, Manuel Simões, Anabela Borges
Opublikowane w: Pharmacological Reviews, Numer 77, 2025, ISSN 0031-6997
Wydawca: Elsevier BV
DOI: 10.1016/J.PHARMR.2025.100038

Biocides as drivers of antibiotic resistance: A critical review of environmental implications and public health risks

Autorzy: Mariana Sousa, Idalina Machado, Lúcia C. Simões, Manuel Simões
Opublikowane w: Environmental Science and Ecotechnology, Numer 25, 2025, ISSN 2666-4984
Wydawca: Elsevier BV
DOI: 10.1016/J.ESE.2025.100557

Current microbiological challenges in drinking water

Autorzy: Ana C. Afonso, Maria J. Saavedra, Inês B. Gomes, Manuel Simões, Lúcia C. Simões
Opublikowane w: Journal of Water Process Engineering, Numer 72, 2025, ISSN 2214-7144
Wydawca: Elsevier BV
DOI: 10.1016/J.JWPE.2025.107614

The ability of Salmonella enterica subsp. enterica strains to form biofilms on abiotic surfaces and their susceptibility to selected essential oil components

Autorzy: Pérez-Lavalle, Liliana; Borges, Anabela; Gomes, Inês; Carrasco, Elena; Valero, Antonio; Simões, Manuel
Opublikowane w: Letters Applied Microbiology, Numer 78, ISSN 1472-765X
Wydawca: Oxford Academi
DOI: 10.1093/LAMBIO/OVAF032

AHL-based QS signalling promotes uropathogenic Escherichia coli settlement through the de-repression of biofilm formation by SdiA

Autorzy: Celia Mayer, Fadi Soukarieh, Manuel Simões, Saskia-Camille Flament-Simon, Miguel Cámara, Manuel Romero
Opublikowane w: PLOS One, Numer 20, 2025, ISSN 1932-6203
Wydawca: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PONE.0328837

The impact of methylparaben and chlorine on the architecture of Stenotrophomonas maltophilia biofilms

Autorzy: Ana Rita Pereira, Liam M. Rooney, Inês B. Gomes, Manuel Simões, Gail McConnell
Opublikowane w: Science of The Total Environment, Numer 951, 2024, ISSN 0048-9697
Wydawca: Elsevier BV
DOI: 10.1016/J.SCITOTENV.2024.175646

Dual action of benzaldehydes: Inhibiting quorum sensing and enhancing antibiotic efficacy for controlling Pseudomonas aeruginosa biofilms

Autorzy: Miguel M. Leitão, Tatiana F. Vieira, Sérgio F. Sousa, Fernanda Borges, Manuel Simões, Anabela Borges
Opublikowane w: Microbial Pathogenesis, Numer 191, 2024, ISSN 0882-4010
Wydawca: Elsevier BV
DOI: 10.1016/J.MICPATH.2024.106663

Antibacterial Effects of Novel Quaternary Ammonium and Phosphonium Salts against Staphylococcus aureus

Autorzy: Nunes, Bárbara; Cagide, Feranando; Borges, Anabela; Borges, Fernanda; Simões, Manuel
Opublikowane w: Journal of Applied Microbiology, ISSN 1365-2672
Wydawca: Oxford Academcic
DOI: 10.1093/JAMBIO/LXAF122

Exploring grape pomace extracts for the formulation of new bioactive multifunctional chitosan/alginate-based hydrogels for wound healing applications

Autorzy: Lília S. Teixeira, Mariana Sousa, Francisca Massano, Anabela Borges
Opublikowane w: Food Bioscience, Numer 62, 2025, ISSN 2212-4292
Wydawca: Elsevier BV
DOI: 10.1016/J.FBIO.2024.105073

Other (3)

COMMUNICATION, DISSEMINATION AND EXPLOITATION PLAN FOR THE INNOVANTIBIOFILM PROJECT

Autorzy: Simões, Manuel; Borges, Anabela; Gomes, Inês
Opublikowane w: ZENODO, 2024
DOI: 10.5281/ZENODO.14753656

GUIDELINES FOR STAFF EXCHANGE OF THE INNOVANTIBIOFILM PROJECT

Autorzy: Simões, Manuel; Oliveira Afonso, Ana Cristina; Gomes, Inês; Borges, Anabela
Opublikowane w: ZENODO, 2025
DOI: 10.5281/ZENODO.15280872

DATA MANAGEMENT PLAN FOR THE INNOVANTIBIOFILM PROJECT

Autorzy: Simões, Manuel; Oliveira Afonso, Ana Cristina; Gomes, Inês; Borges, Anabela
Opublikowane w: ZENODO, 2025
DOI: 10.5281/ZENODO.15280816