Project description
Transforming cultivated meat products' scale-up potential and quality
Meat demand is expected to double by 2050, yet consumption must decrease by 50 % to mitigate greenhouse gases and conserve land. Cultivated meat offers a viable alternative, but the industry faces challenges regarding production costs, scalability and product quality. ProFuse has developed a cell line for muscle tissue proliferation and differentiation, along with a media supplement that simulates natural muscle development. The company has created preliminary supplement formulations for various 2D and 3D applications. In this context, the EIC-funded PROFUSE project aims to optimise the cell line and supplement combination for 3D production techniques. It will validate this solution with three clients and attain technology readiness level 6. The success of the project will revolutionise the potential scale-up and quality of cultivated meat products.
Objective
Whilst meat demand is expected to double by 2050, consumption needs to drop by 50% to reduce greenhouse gases and preserve land. Cultivated meat - meat products manufactured through the harvesting and proliferation of animal cells - offers a feasible alternative, supplying animal protein at minimal environmental costs. However, the industry faces significant challenges linked to production costs, ability to scale-up, and final product quality. The main technical bottlenecks arise from the need to continuously source cells from live animals, and inefficient differentiation and maturation processes, that fail to achieve nutritional and organoleptic characteristics to satisfy consumers. Harnessing unique expertise on muscle cultivation, ProFuse has developed the first spontaneously immortalized and stable myoblast cell line (bovine) with remarkable proficiency in both muscle tissue proliferation and differentiation. Secondly, ProFuse has formulated a media supplement capable of driving the highly effective fusion and maturation into contractile muscle, successfully mimicking natural muscle development. After receiving the licensing of the patent protecting the discovery and the incorporation of our start-up for boosting development and commercialization, our team has established strong relationships with worldwide leading cultivated meat producers and suppliers, developing initial supplement formulations for different 2D and 3D applications. Through this project, we aim at optimizing our combined cell-line + supplement solution for scale-up enabling 3D production techniques up to reaching the validation in relevant environment with at least 3 potential clients while preparing the certification dossier, thus bringing our combined cell-line + supplement solution to TRL6. ProFuse will transform the scale-up potential and quality of final cultivated meat products, fast forwarding the industry to high uptake scenarios.
Fields of science (EuroSciVoc)
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Keywords
Programme(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Funding Scheme
HORIZON-EIC - HORIZON EIC GrantsCoordinator
00000 KIRYAT SHMONA
Israel
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.