Project description
Advancing assessment of endocrine-disrupting chemicals
Endocrine-disrupting chemicals (EDCs) interfere with the endocrine (hormone) system and consequently cause adverse health effects. Exposure to EDCs can negatively affect both humans and the environment, and there is a need for advanced methods to accurately assess them. With the support of the Marie Skłodowska-Curie Actions programme, the NeXED project brings together experts from academia, industry, and regulatory agencies to advance the field of EDC assessment. By recognising the interconnectedness of human health, animal health, and the environment, they will train doctoral candidates in a One Health approach, integrating human and environmental EDC assessment. The consortium proposes to develop new test methods and to assess the impact of complex EDC mixtures rather than single compounds.
Objective
The EU has flagged endocrine disrupting chemicals (EDCs), which interfere with normal hormonal function leading to adverse health effects, of particular concern. Within different EU regulatory programmes the assessment of EDCs has recently changed significantly and continues to evolve rapidly. Advances in test methods for assessment of EDCs are needed to meet these changing regulatory requirements, and a new generation of toxicologists must be trained to support the implementation of the most advanced approaches. NeXED will address three critical challenges in this area. First, human and environmental EDC assessment have historically been separate disciplines while there is an increasing need to use data across species in a One Health approach. Second, EDC assessment currently addresses single compounds while in an environmentally realistic scenario organisms are faced with complex mixtures of EDCs. Third, new test methods for EDC assessment are needed, covering less well-characterised mechanisms and effects. NeXED aims to facilitate a paradigm shift in EDC assessment by training a new generation of cross-disciplinary toxicologists specialised in using harmonised approaches in a One Health framework. NeXED will train its 15 doctoral candidates through research, secondments and training events using an interdisciplinary and intersectoral training programme. NeXED brings together 9 Beneficiaries and 11 Associated Partners from 10 countries, building upon long-standing collaborations through existing projects including the Horizon 2020 EURION projects and the Horizon Europe Partnership on the Assessment of Risk from Chemicals (PARC). The consortium includes leading researchers from institutions with excellent doctoral training programmes who are all experts in ED assessment, as well as industry partners, regulatory agencies, SMEs and consultancy firms. With its complementary expertise the consortium is ideally placed to train the NeXED generation of toxicologists.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-DN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2000 Antwerpen
Belgium
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Participants (8)
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5230 Odense M
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1081 HV Amsterdam
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601 77 Brno
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75794 PARIS
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2800 KONGENS LYNGBY
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171 77 STOCKHOLM
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20122 Milano
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91000 Evry
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Partners (11)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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SO17 1BJ SOUTHAMPTON
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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76337 WALDBRONN
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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162 00 Prague
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
5000 Odense
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3721 MA Bilthoven
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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1060 Bruxelles / Brussel
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2027 Kjeller
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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40223 Düsseldorf
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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75006 PARIS
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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75005 Paris
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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SW1P 4DF LONDON
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The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.