Skip to main content
European Commission logo
español español
CORDIS - Resultados de investigaciones de la UE
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary

Network for Cross-disciplinary assessment of Endocrine Disrupting compounds: training the next generation of toxicologists

Descripción del proyecto

DE EN ES FR IT PL

Avanzar en la evaluación de los alteradores endocrinos

Los alteradores endocrinos (AE) interfieren en el sistema endocrino (hormonal) y, en consecuencia, provocan efectos adversos para la salud. La exposición a las AE puede afectar negativamente tanto a los seres humanos como al medio ambiente, por lo que se necesitan métodos avanzados para evaluarlas con precisión. El proyecto NeXED, que cuenta con el apoyo de las Acciones Marie Skłodowska-Curie, reúne a expertos del mundo universitario y la comunidad científica e investigadora, la industria y las agencias reguladoras para avanzar en el campo de la evaluación de los AE. Al reconocer la interconexión de la salud humana, la sanidad animal y el medio ambiente, formarán a los doctorandos en el enfoque de «Una sola salud», integrando la evaluación de los AE humanos y ambientales. El consorcio propone crear nuevos métodos de ensayo y evaluar los efectos de las mezclas complejas de AE en lugar de los compuestos aislados.

Objetivo

The EU has flagged endocrine disrupting chemicals (EDCs), which interfere with normal hormonal function leading to adverse health effects, of particular concern. Within different EU regulatory programmes the assessment of EDCs has recently changed significantly and continues to evolve rapidly. Advances in test methods for assessment of EDCs are needed to meet these changing regulatory requirements, and a new generation of toxicologists must be trained to support the implementation of the most advanced approaches. NeXED will address three critical challenges in this area. First, human and environmental EDC assessment have historically been separate disciplines while there is an increasing need to use data across species in a One Health approach. Second, EDC assessment currently addresses single compounds while in an environmentally realistic scenario organisms are faced with complex mixtures of EDCs. Third, new test methods for EDC assessment are needed, covering less well-characterised mechanisms and effects. NeXED aims to facilitate a paradigm shift in EDC assessment by training a new generation of cross-disciplinary toxicologists specialised in using harmonised approaches in a One Health framework. NeXED will train its 15 doctoral candidates through research, secondments and training events using an interdisciplinary and intersectoral training programme. NeXED brings together 9 Beneficiaries and 11 Associated Partners from 10 countries, building upon long-standing collaborations through existing projects including the Horizon 2020 EURION projects and the Horizon Europe Partnership on the Assessment of Risk from Chemicals (PARC). The consortium includes leading researchers from institutions with excellent doctoral training programmes who are all experts in ED assessment, as well as industry partners, regulatory agencies, SMEs and consultancy firms. With its complementary expertise the consortium is ideally placed to train the NeXED generation of toxicologists.

Palabras clave

Programa(s)

Tema(s)

Convocatoria de propuestas

HORIZON-MSCA-2023-DN-01

Consulte otros proyectos de esta convocatoria

Régimen de financiación

HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks

Coordinador

UNIVERSITEIT ANTWERPEN
Aportación neta de la UEn
€ 787 860,00
Dirección
PRINSSTRAAT 13
2000 Antwerpen
Bélgica

Ver en el mapa
Región
Vlaams Gewest Prov. Antwerpen Arr. Antwerpen
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
Sin datos

Participantes (8)

Socios (11)

Compartir esta página

Descargar

Última actualización: 4 Julio 2024

Mi folleto

Permalink: https://cordis.europa.eu/project/id/101168892/es

European Union, 2025