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New chemical warheads for covalent drug discovery

Objetivo

Over the past two decades, the pharmaceutical industry has witnessed an exponential growth in approved covalent drugs. The majority of such drugs incorporate a chemical warhead, a mild electrophilic reactive functional group that forms covalent bonds in a reversible or irreversible manner with nucleophilic aminoacid residues. The aim of this proposal is to assess the viability of a new chemical warhead in the discovery of novel kinase inhibitors.

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Institución de acogida

FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA
Aportación neta de la UEn
€ 150 000,00
Dirección
AVENIDA PAISSOS CATALANS 16
43007 Tarragona
España

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Este Cataluña Tarragona
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Beneficiarios (1)