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New chemical warheads for covalent drug discovery

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Over the past two decades, the pharmaceutical industry has witnessed an exponential growth in approved covalent drugs. The majority of such drugs incorporate a chemical warhead, a mild electrophilic reactive functional group that forms covalent bonds in a reversible or irreversible manner with nucleophilic aminoacid residues. The aim of this proposal is to assess the viability of a new chemical warhead in the discovery of novel kinase inhibitors.

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FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA
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€ 150 000,00
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AVENIDA PAISSOS CATALANS 16
43007 Tarragona
Spanien

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Este Cataluña Tarragona
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