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New chemical warheads for covalent drug discovery

Objectif

Over the past two decades, the pharmaceutical industry has witnessed an exponential growth in approved covalent drugs. The majority of such drugs incorporate a chemical warhead, a mild electrophilic reactive functional group that forms covalent bonds in a reversible or irreversible manner with nucleophilic aminoacid residues. The aim of this proposal is to assess the viability of a new chemical warhead in the discovery of novel kinase inhibitors.

Mots‑clés

Institution d’accueil

FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA
Contribution nette de l'UE
€ 150 000,00
Adresse
AVENIDA PAISSOS CATALANS 16
43007 Tarragona
Espagne

Voir sur la carte

Région
Este Cataluña Tarragona
Type d’activité
Research Organisations
Liens
Coût total
Aucune donnée

Bénéficiaires (1)