Project description
Tackling Mpox: A genomic approach to a growing crisis
A deadly outbreak of Mpox, a re-emerging viral zoonotic disease, is wreaking havoc in sub-Saharan Africa, particularly in the Democratic Republic of Congo (DRC). Thousands of suspected cases and hundreds of deaths have alarmed health authorities, leading the DRC to declare a Public Health Emergency in April 2024. The rapid transmission and high mortality rate of Mpox make it a pressing public health threat. Urgent research and intervention are needed to contain the situation. To tackle this crisis, the EU-funded ODIN-MPox project is using advanced genomic surveillance and wastewater-based epidemiology. The project aims to track the presence of the virus in the environment, guiding targeted public health actions to control the outbreak and prevent future epidemics.
Objective
Mpox, a re-emerging viral zoonotic disease, has recently posed significant public health challenges in sub-Saharan Africa, particularly in the Democratic Republic of Congo (DRC). The disease has led to thousands of suspected cases and hundreds of deaths, prompting the DRC Ministry of Health to declare a Public Health Emergency in April 2024. Given the rapid spread and high fatality rate of the outbreak, a coordinated research response is urgently needed to understand and mitigate this public health threat.
Mpox's emergence as a significant public health threat in sub-Saharan Africa aligns with Project ODIN's core objective of addressing critical infectious pathogens through genomic surveillance and wastewater-based epidemiology. Building upon the successful foundation of Project ODIN, this proposal aims to implement a comprehensive water genomic surveillance system specifically targeting the Mpox outbreak in the DRC and neighboring countries.
By leveraging advanced genomic surveillance and wastewater-based epidemiology, this initiative will provide novel, critical, and timely insights into the presence and spread of the Mpox virus in the environment. This information will guide targeted public health interventions, such as targeted vaccination campaigns and resource allocation to high-risk areas. Additionally, the approach will enable the early detection of the Mpox virus in water sources, allowing for rapid public health interventions to prevent further transmission.
The project will identify Mpox virus sublineages with the highest impact on case numbers and fit them into a global context, providing evidence of international sublineages that likely emerged or spread early in the DRC and neighboring countries. This data will be crucial not only in addressing the immediate outbreak but also in contributing to building global public health strategies and preparedness for future outbreaks by gaining a deeper understanding of the Mpox virus itself.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental engineering water treatment processes wastewater treatment processes
- medical and health sciences health sciences public health epidemiology epidemics prevention
- natural sciences biological sciences microbiology virology
- medical and health sciences health sciences public health epidemiology zoonosis
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.1 - Health
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-JU-RIA - HORIZON JU Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-JU-GH-EDCTP3-2024-Mpox
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
22100 Lund
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.