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Encapsulation of bioactive compounds from cherry waste with acetate-producing bacteria for the increase of intestinal butyrogenic bacteria

Project description

Turning cherry waste into gut health solutions

Revalorising cherry waste offers new circular business opportunities in health. Supported by the Marie Skłodowska-Curie Actions programme, the PRECAP project will transform cherry waste (Prunus avium L.) into functional capsules for the European circular economy. It focuses on encapsulating prebiotic compounds, such as dietary fibre and proanthocyanidins, alongside acetate-producing bacteria (Bifidobacterium or Lactobacillus) to restore healthy butyrogenic bacteria in the gut microbiome. These capsules aim to prevent or reduce inflammatory bowel diseases linked to low butyrate levels, providing a promising approach to improving public health.

Objective

This PRECAP project aims to revalorize cherry waste (Prunus avium L.) from agricultural industry by bringing a new approach to the European circular economy. PRECAP by encapsulating prebiotic bioactive compounds extracted from cherry waste (dietary fiber and proanthocyanidins) and acetate producing bacteria (Bifidobacterium or Lactobacillus, that consume these biocompounds), seek to restore the health concentrations of butyrogenic bacteria in the intestinal microbiome, which consume acetate by cross-feeding to produce butyrate. The project stands out for its innovation in the development of functional capsules to prevent or mitigate inflammatory bowel diseases derived from the reduction of butyrate produced by the intestinal microbiome.
Furthermore, this is enhanced by the healthy nutraceutical effect of phenolic compounds and dietary fiber extracted from cherry waste. The design of this functional capsule of potential probiotic bacteria that produce acetate together with prebiotics from cherry waste, added to the application of a scalable encapsulation methodology (spray-dryer), could be the basis for the development of functional foods from agro-industrial waste. Acetate-producing bacteria are more aerotolerant than butyrogenic (strictly anaerobic) bacteria, which would allow more feasible scalability and management projection in the food industry. Finally, PRECAP is expected to improve the competitiveness, sustainability, and circular economy of agri-food chains, and be a viable alternative to improve people's health.

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

UNIVERSIDAD DE EXTREMADURA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 242 593,20
Address
AVENIDA DE ELVAS SN
06006 BADAJOZ
Spain

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Region
Centro (ES) Extremadura Badajoz
Activity type
Higher or Secondary Education Establishments
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Total cost

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