Skip to main content
Weiter zur Homepage der Europäischen Kommission (öffnet in neuem Fenster)
Deutsch de
CORDIS - Forschungsergebnisse der EU
CORDIS

Ampli-sCiSsoRS: amplified backscattering coherent Stokes Raman scattering for real-time cancer diagnostics

Ziel

Coherent Raman imaging can provide rapid, label-free virtual histology, but its clinical translation is constrained by detection geometry and detector noise. Standard stimulated Raman scattering relies on forward detection, which is poorly suited to thick, highly scattering tissue and therefore limits intraoperative implementations. In our ERC-funded research, we introduced backscattering coherent Stokes Raman scattering (b-CSRS), a coherent Raman modality whose red-shifted emission enables epi detection and is compatible with laser scanning and spectrally resolved acquisition. However, current b-CSRS detection is limited by detector noise, preventing shot-noise-limited, high-speed imaging and spectroscopy.

This Proof-of-Concept will remove that bottleneck by developing a compact, low-noise amplified readout strategy for b-CSRS, enabling improved sensitivity, speed, and spectral fidelity in detector-friendly operating regimes. The project will deliver an alignment-robust readout module compatible with laser-scanning microscopes, quantitative benchmarks against current direct detection approaches, and a validated route toward parallel, multi-channel spectroscopic b-CSRS for tissue classification. Together, these advances will transform b-CSRS from a promising laboratory method into a scalable platform for real-time molecular tissue assessment.

Wissenschaftliches Gebiet (EuroSciVoc)

Programm/Programme

Thema/Themen

Finanzierungsplan

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

Alle im Rahmen dieses Finanzierungsinstruments finanzierten Projekte anzeigen

Aufforderung zur Vorschlagseinreichung

(öffnet in neuem Fenster) ERC-2026-POC

Alle im Rahmen dieser Aufforderung zur Einreichung von Vorschlägen finanzierten Projekte anzeigen

Gastgebende Einrichtung

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Netto-EU-Beitrag
€ 150 000,00
Adresse
RUE MICHEL ANGE 3
75794 Paris
Frankreich
Region
Ile-de-France Ile-de-France Paris
Aktivitätstyp
Research Organisations
Links
Gesamtkosten
Keine Daten

Begünstigte (1)