Alzheimers Disease Apolipoprotein Pathology for Treatment Elucidation and Development - Sofia ref.: 115975 | ADAPTED | Project | Results | H2020 | CORDIS

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Definition of cognitive composite scores to evaluate rate of disease progression based on cognitive function decline in the ADAPTED cohorts

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Association of lysophosphatidic acids with cerebrospinal fluid biomarkers and progression to Alzheimer’s disease

Autori: Shahzad Ahmad, Adelina Orellana, Isabelle Kohler, Lutz Frölich, Itziar de Rojas, Silvia Gil, Mercè Boada, Isabel Hernández, Lucrezia Hausner, Margot H. M. Bakker, Alfredo Cabrera-Socorro, Najaf Amin, Alfredo Ramírez, Agustín Ruiz, Thomas Hankemeier, Cornelia M. Van Duijn
Pubblicato in: Alzheimer's Research & Therapy, Numero 12/1, 2020, ISSN 1758-9193
Editore: BioMed Central
DOI: 10.1186/s13195-020-00680-9

Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer’s disease

Autori: M. E. Sáez, A. González-Pérez, B. Hernández-Olasagarre, A. Beà, S. Moreno-Grau, I. de Rojas, G. Monté-Rubio, A. Orellana, S. Valero, J. X. Comella, D. Sanchís, A. Ruiz
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-52724-2

PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment

Autori: Luca Kleineidam, Vincent Chouraki, Tomasz Próchnicki, Sven J. van der Lee, Laura Madrid-Márquez, Holger Wagner-Thelen, Ilker Karaca, Leonie Weinhold, Steffen Wolfsgruber, Anne Boland, Pamela V. Martino Adami, Piotr Lewczuk, Julius Popp, Frederic Brosseron, Iris E. Jansen, Marc Hulsman, Johannes Kornhuber, Oliver Peters, Claudine Berr, Reinhard Heun, Lutz Frölich, Christophe Tzourio, Jean-Franç
Pubblicato in: Acta Neuropathologica, Numero 139/6, 2020, Pagina/e 1025-1044, ISSN 0001-6322
Editore: Springer Verlag
DOI: 10.1007/s00401-020-02138-6

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

Autori: Sven J. van der Lee, Charlotte E. Teunissen, René Pool, Martin J. Shipley, Alexander Teumer, Vincent Chouraki, Debora Melo van Lent, Juho Tynkkynen, Krista Fischer, Jussi Hernesniemi, Toomas Haller, Archana Singh-Manoux, Aswin Verhoeven, Gonneke Willemsen, Francisca A. de Leeuw, Holger Wagner, Jenny van Dongen, Johannes Hertel, Kathrin Budde, Ko Willems van Dijk, Leonie Weinhold, M. Arfan Ikram,
Pubblicato in: Alzheimer's & Dementia, 2018, ISSN 1552-5260
Editore: Elsevier BV
DOI: 10.1016/j.jalz.2017.11.012

Blood-derived integration-free iPS cell line UKBi011-A from a diagnosed male Alzheimer's disease patient with APOE ɛ4/ɛ4 genotype

Autori: Michael Peitz, Tamara Bechler, Catrin Cornelia Thiele, Monika Veltel, Melanie Bloschies, Klaus Fliessbach, Alfredo Ramirez, Oliver Brüstle
Pubblicato in: Stem Cell Research, Numero 29, 2018, Pagina/e 250-253, ISSN 1873-5061
Editore: Elsevier
DOI: 10.1016/j.scr.2018.04.011

A perfused human blood–brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport

Autori: Nienke R. Wevers, Dhanesh G. Kasi, Taylor Gray, Karlijn J. Wilschut, Benjamin Smith, Remko van Vught, Fumitaka Shimizu, Yasuteru Sano, Takashi Kanda, Graham Marsh, Sebastiaan J. Trietsch, Paul Vulto, Henriëtte L. Lanz, Birgit Obermeier
Pubblicato in: Fluids and Barriers of the CNS, Numero 15/1, 2018, ISSN 2045-8118
Editore: BioMed Central
DOI: 10.1186/s12987-018-0108-3

CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers

Autori: Shahzad Ahmad, Marta del Campo Milan, Oskar Hansson, Ayse Demirkan, Ruiz Agustin, Maria E. Sáez, Nikolaos Giagtzoglou, Alfredo Cabrera-Socorro, Margot H. M. Bakker, Alfredo Ramirez, Thomas Hankemeier, Erik Stomrud, Niklas Mattsson-Carlgren, Philip Scheltens, Wiesje M. van der Flier, M. Arfan Ikram, Anders Malarstig, Charlotte E. Teunissen, Najaf Amin, Cornelia M. van Duijn
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-65038-5

Alzheimers Disease Apolipoprotein Pathology for Treatment Elucidation and Development - Sofia ref.: 115975

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