Obiettivo The aim of this project is to develop a method for characterization of the structure and dynamics of polycrystals on length scales from the atomic-level to that of the sample. The method, TotalCryst, determines the atomic arrangement within each grain as w ell as the 3D position and morphology of the grains.The structure of each grain can be solved and refined with accuracy presently obtainable only by studies of large single crystals. The method applies to inorganic structures as well as macromolecules and probes grains on all length scales from 100 nm to 1 mm. In this project it will be applied to studies within:Chemistry: TotalCryst will enable the identification and structural quantification of numerous complex or dilute structures which cannot be characterized by present methods. The method may find a widespread use in the pharmaceutical industry.Firstly, it accelerates the process of structure determination, a bottleneck in the process of registration of a new drug. Secondly, it enables characterization of drug content, polymorphism and homogeneity in tablets. Structural biology: Attempting to solve ever-larger structures, crystal quality and radiation sensitivity are major concerns. TotalCryst is a novel strategy for overcoming these issues.Time-resolved studies: TotalCryst offers a number of attractive and unique properties making it highly suitable for time-resolved studies. This includes conventional dynamic studies with time constants of the order of seconds as well as studies in the nano- to femt o-second regime based on stroboscopic methods involving a laser pump / X-ray probe scheme.An example is the possibility to, for the first time, study photo-sensitive materials, e.g. photoactive switches for photovoltaic devices and pigments. The consortium comprises a group of crystallographers, X-ray physicists and computer scientists as well as experts in pharmacy, structural biology and time-resolved studies. Campo scientifico agricultural sciencesagriculture, forestry, and fisheriesagriculturegrains and oilseedsnatural sciencesearth and related environmental sciencesgeologymineralogycrystallographymedical and health sciencesbasic medicinepharmacology and pharmacynatural sciencesbiological sciencesmolecular biologystructural biologynatural sciencesphysical sciencesopticslaser physics Parole chiave Structural biology photochemistry time-resolved diffraction Programma(i) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) NEST-2003-1 - Adventure activities Invito a presentare proposte FP6-2003-NEST-B-3 Vedi altri progetti per questo bando Meccanismo di finanziamento STREP - Specific Targeted Research Project Coordinatore DANMARKS TEKNISKE UNIVERSITET (TECHNICAL UNIVERSITY OF DENMARK) Contributo UE Nessun dato Indirizzo Anker Engelunds Vej 1 KGS. LYNGBY Danimarca Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (7) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto FORSKNINGSCENTER RISØ - RISØ NATIONAL LABORATORY Danimarca Contributo UE Nessun dato Indirizzo Frederiksborgvej 399 ROSKILDE Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato FYZIKALNIUSTAV AV CR Cechia Contributo UE Nessun dato Indirizzo Na Slovance 2 PRAGUE Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato INSTALLATION EUROPÉENNE DE RAYONNEMENT SYNCHROTRON Francia Contributo UE Nessun dato Indirizzo 6, rue Jules Horowitz GRENOBLE Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. Germania Contributo UE Nessun dato Indirizzo Hofgartenstrasse 8 MUENCHEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato NOVO NORDISK A/S Danimarca Contributo UE Nessun dato Indirizzo Novo Alle 1 BAGSVÆRD Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Regno Unito Contributo UE Nessun dato Indirizzo University Offices, Wellington Square OXFORD Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato THE GRADUATE CENTER OF THE CITY UNIVERSITY OF NEW YORK Stati Uniti Contributo UE Nessun dato Indirizzo 365 Fifth Avenue NEW YORK, NY Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato
