Inossia Cement Softener - a new and unique additive to bone cements to revolutionise the treatment of vertebral fractures in osteoporotic patients

Project Information

SMART-SOFT

Grant agreement ID: 190175074

DOI 10.3030/190175074

EC signature date 14 July 2023

Start date 1 August 2023

End date 31 July 2025

Funded under

• The European Innovation Council (EIC)

Total cost € 3 283 325,25

EU contribution € 2 298 325,00

Coordinated by

INOSSIA AB
Sweden

Project description

Additive to bone cements to improve osteoporosis treatment

Bone cements, which can be moulded, implanted as a paste, and set within the body, are widely used in orthopaedic surgery. In this context, the EU-funded SMART-SOFT project aims to develop an innovative solution called Inossia Cement Softener to revolutionise the treatment of osteoporosis and promote healthy, active ageing. Specifically, it is an additive for bone cements that reduces their stiffness by more than 50 %, adjusting it to better match the bone into which it is injected. This adjustment minimally impacts spinal biomechanics and reduces the risk of new vertebral fractures by 75 %. This solution has the potential to significantly improve the outcomes of vertebral augmentation treatments for osteoporotic patients and decrease healthcare costs.

Objective

The Inossia Cement Softener is an additive (a softener) for bone cements that lowers their stiffness by 50-75% and adjusts it to that of the bone it is injected into. This does not alter the spinal biomechanics to the extent that the currently used cements do which in turn reduces the risk of new unnecessary vertebral fractures by 75%.
The Inossia Cement Softener has the potential to become a true game-changer and revolutionise the outcome of vertebral augmentation treatments in osteoporotic patients:

the patients will experience immediate pain relief, allowing them to go back to everyday life without the risk of rehospitalization,
the clinicians will be able to offer an efficient treatment
the healthcare payers will save money previously unnecessary spent on the retreatment of already treated patients

Our innovation is designed to revolutionise the treatment of osteoporosis, ensuring a healthy and active ageing.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• natural sciences › biological sciences › biophysics

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Keywords

• vertebral augmentation
• osteoporosis
• vertebral fractures
• bone cement softener

Programme(s)

• HORIZON.3.1 - The European Innovation Council (EIC) Main Programme

Topic(s)

• HORIZON-EIC-2023-ACCELERATOROPEN-01 - EIC Accelerator Open 2023

Call for proposal

HORIZON-EIC-2023-ACCELERATOR-01

Funding Scheme

HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance

Coordinator

INOSSIA AB

• Net EU contribution: € 2 298 325,00
• Address: IOFFICE KUNGSGATAN 64 ; 111 22 Stockholm ; Sweden
• SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes:
  Region
  Östra Sverige › Stockholm › Stockholms län
• Region: Östra Sverige › Stockholm › Stockholms län
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Total cost: € 3 283 325,25