Objetivo In the production of fine chemicals the downstream processing may amount up to 75 % of the total manufacturing costs, particularly when the product is aimed at nutritional or therapeutic use which demands a maximum purity. Current downstream processing strategies can face limitations whenever existing purification and separation processes are based on physico-chemical principles and thus exhibit a far more limited selectivity for the target compounds than is known from interactions involving biomolecules. The latter, on the other hand, are less robust and often require specific operating conditions (typically close to ambient) and feed compositions, which often restricts their broad application. This proposal presents an innovative, interdisciplinary approach on designing selective and tuneable interfaces for sensors and separations to be employed in downstream processing techniques. By combining recent advances in biology/biochemistry and chemistry and applying them to chemical engineering principles, the approach goes beyond concepts currently known, involving primarily engineered nucleic acids (aptamers) and tuneable ionic liquids (IL) incorporated in an appropriate support structure. The aim of this proposal is to make use of the unique properties of both biomolecules and ionic liquids in order to create supported mixed-matrix interfaces which exhibit properties that bulk materials can hardly achieve. Another novelty of this proposal is the aim to develop these interfaces in a modular way, namely by joining individually optimised elements during interface design in order to yield the desired overall properties. This approach warrants a maximum of degrees of freedom in the overall interface design while keeping the basic interface architecture constant, and thus overcomes one of the limitations that many conventional separation/purification techniques encounter during optimisation of the bulk material. Ámbito científico natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsengineering and technologychemical engineering Palabras clave downstream processing membrane technology separation science Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-SG-PE6 - ERC Starting Grant - Computer science and informatics Convocatoria de propuestas ERC-2007-StG Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-SG - ERC Starting Grant Institución de acogida UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA Aportación de la UE € 1 397 997,06 Dirección BARRIO SARRIENA S N 48940 Leioa España Ver en el mapa Región Noreste País Vasco Bizkaia Tipo de actividad Higher or Secondary Education Establishments Investigador principal Thomas Schäfer (Dr.) Contacto administrativo Ione Isasa (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (2) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA España Aportación de la UE € 1 397 997,06 Dirección BARRIO SARRIENA S N 48940 Leioa Ver en el mapa Región Noreste País Vasco Bizkaia Tipo de actividad Higher or Secondary Education Establishments Investigador principal Thomas Schäfer (Dr.) Contacto administrativo Ione Isasa (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos UNIVERSITAT ROVIRA I VIRGILI La participación finalizó España Aportación de la UE € 100 140,94 Dirección CARRER DE ESCORXADOR 43003 Tarragona Ver en el mapa Región Este Cataluña Tarragona Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo María Belén Serrano Santos (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos