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Tissue Transmigration Training Network

Objective

Cardiovascular and cancer-related diseases are the leading causes of human mortality and disability. The underlying mechanisms originate from chronic interstitial cell activation leading to pathological tissue remodelling and malfunction of cells. These depend on three fundamental processes: cell adhesion, migration, and modulation/degradation of the extracellular matrix (ECM), which together determine tissue invasion and remodelling. The proposed ITN Tissue Transmigration Training Network (T3Net) is aimed at promoting excellence in training in these areas, with an emphasis on cutting-edge technologies and complementary skills training. T3Net is very timely and has a multidisciplinary training approach unavailable within a single country of the EU. T3Net will be crucial in bundling current and future European expertise and to thus consolidate the momentary European leadership in these emerging key areas of biomedical research. The academic and industrial partners will provide training in new areas of research including the cell structures mediating invasion such as podosomes and invadopodia, as well as the application of materials sciences, nanotechnology and state-of-the-art in vivo imaging. These techniques will be applied to study ECM-cell interactions, in models encompassing vascular remodelling, immunity, inflammation and bone physiology, as well as the pathophysiology of cancer invasion. T3Net trainees will thus be at the forefront of current research, with innovative, complementary expertise in ECM remodelling and tissue transmigration in physiology and pathology. They will also benefit from valuable complementary skills training including communication, entrepreneurship and intellectual property rights. The strength and appeal of the T3Net proposal thus lies in the unique prospect to establish a long-term European network based on a new cohort of young professionals with the potential to exploit their knowledge in academic, clinical or industrial settings.

Call for proposal

FP7-PEOPLE-ITN-2008
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Address
Martinistrasse 52
20251 Hamburg
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 616 196
Administrative Contact
Stefan Linder (Prof.)

Participants (7)

STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 202 535
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maarten Van Langen (Mr.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 405 754
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
Jean Rosenbaum (Dr.)
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 373 594
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Talia Tzahor (Ms.)
Excellness Biotech SA
Switzerland
EU contribution
€ 444 977
Address
Parc Scientifique Epfl, Pse-c
1015 Lausanne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pierre-Jean Wipff (Dr.)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 213 702
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Labbett (Mr.)
ECOLE NORMALE SUPERIEURE DE LYON
France
EU contribution
€ 207 002
Address
Parvis Rene Descartes 15
69342 Lyon
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Valérie Tessier (Ms.)
FONDAZIONE MARIO NEGRI SUD-CENTRO DI RICERCHE FARMACOLOGICHE EB IOMEDICHE
Italy
EU contribution
€ 393 875
Address
Via Nazionale 8A
66030 Santa Maria Imbaro
Activity type
Research Organisations
Administrative Contact
Claude Alain Di Menno Di Bucchianico (Mr.)