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Tissue Transmigration Training Network

Objectif

Cardiovascular and cancer-related diseases are the leading causes of human mortality and disability. The underlying mechanisms originate from chronic interstitial cell activation leading to pathological tissue remodelling and malfunction of cells. These depend on three fundamental processes: cell adhesion, migration, and modulation/degradation of the extracellular matrix (ECM), which together determine tissue invasion and remodelling. The proposed ITN Tissue Transmigration Training Network (T3Net) is aimed at promoting excellence in training in these areas, with an emphasis on cutting-edge technologies and complementary skills training. T3Net is very timely and has a multidisciplinary training approach unavailable within a single country of the EU. T3Net will be crucial in bundling current and future European expertise and to thus consolidate the momentary European leadership in these emerging key areas of biomedical research. The academic and industrial partners will provide training in new areas of research including the cell structures mediating invasion such as podosomes and invadopodia, as well as the application of materials sciences, nanotechnology and state-of-the-art in vivo imaging. These techniques will be applied to study ECM-cell interactions, in models encompassing vascular remodelling, immunity, inflammation and bone physiology, as well as the pathophysiology of cancer invasion. T3Net trainees will thus be at the forefront of current research, with innovative, complementary expertise in ECM remodelling and tissue transmigration in physiology and pathology. They will also benefit from valuable complementary skills training including communication, entrepreneurship and intellectual property rights. The strength and appeal of the T3Net proposal thus lies in the unique prospect to establish a long-term European network based on a new cohort of young professionals with the potential to exploit their knowledge in academic, clinical or industrial settings.

Appel à propositions

FP7-PEOPLE-ITN-2008
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Coordinateur

UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Adresse
Martinistrasse 52
20251 Hamburg
Allemagne

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Stefan Linder (Prof.)
Contribution de l’UE
€ 616 196

Participants (7)

STICHTING RADBOUD UNIVERSITEIT
Pays-Bas
Contribution de l’UE
€ 202 535
Adresse
Houtlaan 4
6525 XZ Nijmegen

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Maarten Van Langen (Mr.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Contribution de l’UE
€ 405 754
Adresse
Rue De Tolbiac 101
75654 Paris

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Type d’activité
Research Organisations
Contact administratif
Jean Rosenbaum (Dr.)
WEIZMANN INSTITUTE OF SCIENCE
Israël
Contribution de l’UE
€ 373 594
Adresse
Herzl Street 234
7610001 Rehovot

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Talia Tzahor (Ms.)
Excellness Biotech SA
Suisse
Contribution de l’UE
€ 444 977
Adresse
Parc Scientifique Epfl, Pse-c
1015 Lausanne

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Pierre-Jean Wipff (Dr.)
KING'S COLLEGE LONDON
United Kingdom
Contribution de l’UE
€ 213 702
Adresse
Strand
WC2R 2LS London

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Paul Labbett (Mr.)
ECOLE NORMALE SUPERIEURE DE LYON
France
Contribution de l’UE
€ 207 002
Adresse
Parvis Rene Descartes 15
69342 Lyon

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Valérie Tessier (Ms.)
CONSORZIO MARIO NEGRI SUD.
Italie
Contribution de l’UE
€ 393 875
Adresse
Via Nazionale 8/a
66030 Santa Maria Imbaro

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Type d’activité
Research Organisations
Contact administratif
Claude Alain Di Menno Di Bucchianico (Mr.)