Obiettivo
Chromatin packages a few meters of DNA into a nucleus measuring a few microns. This tight folding occurs by assembling DNA with histones into so-called nucleosomes, thus ensuring the mechanical stability of our genome. On the flipside, this makes nucleosomes a formidable obstacle to the machines that read, copy or repair its DNA message. One of the fundamental questions in biology is to understand how nucleosome structure is established, maintained and manipulated. Our Marie Curie Initial Training Network will carry out multidisciplinary, collaborative research projects focused on deciphering nucleosome structure and function in space and time (Nucleosome4D). Our main objective is to provide our young researchers with world-class research & training in nucleosome biology. We will use cutting-edge, interdisciplinary methods and collaborative projects to determine how nucleosomes are remodeled during transcription, when genes are silenced, as cell divide, as stem cells differentiate, during organismal development and in human disease. We utilize state-of-the-art approaches in structural biology, biophysics, cell biology, live-cell imaging, biochemistry, genetics, genomics and bioinformatics. We will implement a comprehensive training plan for scientific and career development using the best local approaches to research & training, by promoting exchanges, using the advise of our industrial partners and three Visiting Scientists, by sharing reagents and expertise, as well as through a structured set of scientific workshops and complementary skills training courses. Together, our effort will ensure the multidisciplinary and intersectorial training of a new cohort of young European researchers. This will allow our trainees to take the opportunities and meet the challenges of a successful career in the life science sector through excellent training, effective communication, great teamwork and proven project management skills.
Campo scientifico
Invito a presentare proposte
FP7-PEOPLE-ITN-2008
Vedi altri progetti per questo bando
Meccanismo di finanziamento
MC-ITN - Networks for Initial Training (ITN)Coordinatore
80539 MUNCHEN
Germania
Mostra sulla mappa
Partecipanti (16)
5020 Bergen
Mostra sulla mappa
75231 Paris
Mostra sulla mappa
6720 Szeged
Mostra sulla mappa
4058 BASEL
Mostra sulla mappa
1165 Kobenhavn
Mostra sulla mappa
28029 Madrid
Mostra sulla mappa
6020 Innsbruck
Mostra sulla mappa
91904 Jerusalem
Mostra sulla mappa
DD1 4HN Dundee
Mostra sulla mappa
W1B 1AL LONDON
Mostra sulla mappa
67404 Illkirch Graffenstaden
Mostra sulla mappa
CB4 0WS Cambridge
Mostra sulla mappa
20133 Milano
Mostra sulla mappa
80539 Munchen
Mostra sulla mappa
60323 Frankfurt Am Main
Mostra sulla mappa
69117 Heidelberg
Mostra sulla mappa