Ziel
The ENIR project aims to carry out a foresight study to investigate the scientific needs in relation to the development of a large and shared European multidimensional repository of high resolution magnetic resonance (MR) images of normal brains and brains with different neurodegenerative disorders (Alzheimer's, amyotrophic lateral sclerosis, Parkinson's disease, etc.) completed by clinical, genetic and neuropsychological data.
The huge variability of brain morphology affects the judgement of what constitutes normality or the comparison among different brain groups. In order to model and manage this variability, a wide amount of brain images and information on the sources of variability is needed. To reach meaningful numbers, such a repository cannot be collected in a single centre, but requires that brain images taken from many centres be pooled. A European repository of this kind does not exist at the present time due to the lack of a structured communication network among centres and of the huge heterogeneity of acquisition protocols and clinical information collected from the patients.
The ENIR project will investigate the needed standardization topics and practical implications in acquisition, processing and storage of neuroimages by means of a co-ordinated approach to the setting up of a devoted research infrastructure, making the best use of those already existing. Consensus will be achieved on a number of currently discordant theoretical and practical issues that have so far hindered the setting up of a large European brain image repository. The proposed study will also identify standardized procedures in order to make the best use of existing repositories, in view of their increased integration towards the development of the future European infrastructure.
Wissenschaftliches Gebiet
- medical and health sciencesbasic medicineneurologydementiaalzheimer
- medical and health sciencesbasic medicinepathology
- engineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imaging
- medical and health sciencesbasic medicineneurologyparkinson
- medical and health sciencesbasic medicineneurologyamyotrophic lateral sclerosis
Thema/Themen
Aufforderung zur Vorschlagseinreichung
FP6-2004-INFRASTRUCTURES-5
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