Skip to main content

Fast-Tracking Pathology via Automated Image Analysis and High-Performance Computing: Application to Prostate Cancer Diagnostics

Objectif

Histopathology has traditionally been a low-throughput, labour-intensive technique. Conventional manual annotation of tissue slides requires a pathologist to examine the tissue and cellular components to grade the level of disease progression. However, digital pathology and automated digital image analysis solutions can provide a more rapid solution. In recent years, there has been a rapid uptake of digital pathology in both the academic and industrial sectors, each creating large image libraries with related manual and automated annotations, all stored on local systems. There is now a requirement to streamline this process and to provide a comprehensive set of tools for data integration and mining of this valuable, but often not fully exploited, information. There is also a need for inter-lab standardisation and the development of high-performance computing approaches to enable integration of multiple libraries and knowledge discovery. The FAST-PATH project will address these key issues to maximise the capabilities of the digital pathology workflow. Specifically, FAST-PATH will develop a set of tools, available through a web-based interface, to address the standardisation, integration and knowledge discovery of high-throughput digital pathology libraries and related manual annotations. We will focus on integration of oncology-based data generated from the academic and industrial partners involved, with a particular emphasis on prostate cancer. This inter-sectoral study will also involve validation of novel prognostic biomarkers via automated analysis of immunohistochemical images. Importantly, FAST-PATH will bring together 4 major European academic institutes and 2 SME partners with the central aim of streamlining digital pathology via the development of data standardisation, integration and discovery tools.

Appel à propositions

FP7-PEOPLE-2011-IAPP
Voir d’autres projets de cet appel

Coordinateur

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Adresse
Belfield
4 Dublin
Irlande
Type d’activité
Higher or Secondary Education Establishments
Contribution de l’UE
€ 357 432
Contact administratif
Donal Doolan (Mr.)

Participants (5)

THE QUEEN'S UNIVERSITY OF BELFAST
United Kingdom
Contribution de l’UE
€ 222 034
Adresse
University Road Lanyon Building
BT7 1NN Belfast
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Colleen Spence (Ms.)
MAX IV Laboratory, Lund University
Suède
Contribution de l’UE
€ 209 946
Adresse
Paradisgatan 5C
22100 Lund
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Lennart Råstam (Mr.)
UPPSALA UNIVERSITET
Suède
Contribution de l’UE
€ 259 160
Adresse
Von Kraemers Alle 4
751 05 Uppsala
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Fredrik Ponten (Prof.)
ONCOMARK LIMITED
Irlande
Contribution de l’UE
€ 534 359
Adresse
172 Rathgar Road Rathgar
Dublin 6 Dublin
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Mairin Rafferty (Dr.)
I-PATH DIAGNOSTICS LIMITED
United Kingdom
Contribution de l’UE
€ 365 396
Adresse
Innovation Centre Unit 2 Ni Science
BT3 9DT Belfast
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Ian Cargill (Mr.)