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Patient-specific predictions for bone treatments

Ziel

CAD-BONE addresses a multidisciplinary research that will transform current technology by radically improving the development of patient-specific computer models for the modelling of bone remodelling/healing to predict short and long-term bone response after surgical interventions. Specifically, CAD-BONE will combine image processing, musculoskeletal modelling tools, finite element analyses and bone remodelling/healing algorithms to provide an understanding of the individual functional outcome of patient treatments from standard clinical radiographs. Although already developed and broadly in use, these computer technologies and methods are yet to be combined and integrated to create a computer tool with a predictive purpose. To successfully achieve this objective different scientific and technological challenges will be faced. Firstly, the automatic construction of patient-specific finite element models of specific bones (including geometries, loads and boundary conditions). Secondly, The improvement of current bone remodelling/healing models, which are very slow, labour-intesive and costly processes, in order to achieve accurate near real-time results; to do so, different strategies based on model reduction techniques will be explored). And, finally, the quantitative validation of these patient-specific models. Such a validation will require a quantitative comparison between real bone density distributions obtained by computer tomography (CT) and those predicted from computer simulations.
Therefore, we expect that CAD-BONE can lead to a preliminary tool for the prediction of bone morphological changes resulting from changes in mechanical loading conditions.

Wissenschaftliches Gebiet (EuroSciVoc)

Programm/Programme

Thema/Themen

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2011-IAPP
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Koordinator

UNIVERSIDAD DE ZARAGOZA
EU-Beitrag
€ 187 601,00
Adresse
CALLE PEDRO CERBUNA 12
50009 Zaragoza
Spanien
Region
Noreste Aragón Zaragoza
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
Keine Daten

Beteiligte (2)