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Contenuto archiviato il 2024-06-18

Patient-specific predictions for bone treatments

Obiettivo

CAD-BONE addresses a multidisciplinary research that will transform current technology by radically improving the development of patient-specific computer models for the modelling of bone remodelling/healing to predict short and long-term bone response after surgical interventions. Specifically, CAD-BONE will combine image processing, musculoskeletal modelling tools, finite element analyses and bone remodelling/healing algorithms to provide an understanding of the individual functional outcome of patient treatments from standard clinical radiographs. Although already developed and broadly in use, these computer technologies and methods are yet to be combined and integrated to create a computer tool with a predictive purpose. To successfully achieve this objective different scientific and technological challenges will be faced. Firstly, the automatic construction of patient-specific finite element models of specific bones (including geometries, loads and boundary conditions). Secondly, The improvement of current bone remodelling/healing models, which are very slow, labour-intesive and costly processes, in order to achieve accurate near real-time results; to do so, different strategies based on model reduction techniques will be explored). And, finally, the quantitative validation of these patient-specific models. Such a validation will require a quantitative comparison between real bone density distributions obtained by computer tomography (CT) and those predicted from computer simulations.
Therefore, we expect that CAD-BONE can lead to a preliminary tool for the prediction of bone morphological changes resulting from changes in mechanical loading conditions.

Campo scientifico (EuroSciVoc)

Argomento(i)

Invito a presentare proposte

FP7-PEOPLE-2011-IAPP
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Meccanismo di finanziamento

MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Coordinatore

UNIVERSIDAD DE ZARAGOZA
Contributo UE
€ 187 601,00
Indirizzo
CALLE PEDRO CERBUNA 12
50009 Zaragoza
Spagna
Regione
Noreste Aragón Zaragoza
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
Nessun dato

Partecipanti (2)