Final Activity Report Summary - SONELTECH (Sonoelectrochemical Technology of Manufacturing a Bioactive Hydroxypatite Coating on Carbon/Carbon Composites)
Sonoelectrodeposition methodology has been developed in this project to produce bioactive CaP, particularly HA, on carbon substrates. Indeed, this technique involves low temperature and allows controlling the thickness, the morphology, and the chemical composition of the coatings through adequate conditions of the process.
However, the success or the failure of the elaborated implants depends on the control and consequences of the cell behaviour after implantation. Thus, the first and essential step for bone tissue-implant interface study is in vitro tests using osteoblast cells. Human osteoblast-like MG63 cell line was used to study the interactions between cells and biomaterial and study the biocompatibility of biomaterials in this project. The cell morphology was assessed by scanning electron microscopy (SEM), and the cell proliferation and viability by biological techniques.
The results showed that CaP coatings prepared by sonoelectrodeposition technique enhance the bioactivity of carbon materials. The morphology, structure and composition of the CaP coatings was shown to be dependent on the specific conditions used in the process and found to have a significant effects on osteoblast / material interaction.