Obiettivo MAILPAN (MAcroencapsulation of PANcreatic Islets) is a prototype of bioartificial pancreas usable in the human designed to treat type 1 diabetic patients. The prototype was developed along different stages since 1996 and led to the creation of the SME called Defymed in 2011. Next step is now to bring the prototype to the pre-clinical and clinical phases necessary to the ensuing commercialization of MAILPAN whose ultimate goal is to improve the life of at least 20 million persons in the world while providing positive effects on healthcare management and expenses, the environment and the competitiveness of the biomaterials industry.In order to reach this goal, CeeD and Defymed gathered a consortium made of seven partners from academia, clinical/public health research sector and industry/SMEs from three different European countries –Belgium, France and UK. The expertise gathered include encapsulation techniques, islet isolation, cell engineering, islet transplantation, islet preconditioning, surgical implantation, and medium formulation; items that are complementary and necessary to the implementation of the present project proposal.The project proposal of a 48-month duration intends to bring the most modern and up to date improvements that the bioartificial pancreas still needs and can receive such as to enhance cells survival inside the device by formulating a new adapted cell culture medium, to further lower the rejection risk by studying the biocompatibility and anti-inflammatory mechanisms, to test the prototype in small and large animal models, and to secure its further use in humans. Safety and bio-compatibility of MAILPAN device combined to the islets/pseudo-islets, will be assessed, in respect to the applied regulatory directives. Campo scientifico medical and health scienceshealth sciencespublic healthmedical and health sciencesclinical medicineendocrinologydiabetesmedical and health sciencesclinical medicinetransplantationengineering and technologyindustrial biotechnologybiomaterials Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH.2012.2.4.3-1 - Innovative approach to manage diabetes Invito a presentare proposte FP7-HEALTH-2012-INNOVATION-1 Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore CENTRE EUROPEEN D'ETUDE DU DIABETE Contributo UE € 812 317,60 Indirizzo BOULEVARD RENE LERICHE 67200 STRASBOURG Francia Mostra sulla mappa Regione Grand Est Alsace Bas-Rhin Tipo di attività Other Contatto amministrativo Severine Sigrist (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (7) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto AvantiCell Science Ltd Regno Unito Contributo UE € 484 927,20 Indirizzo GIBBSYARD BUILDING KA6 5HW Ayr Mostra sulla mappa Regione Scotland Southern Scotland South Ayrshire Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Colin Wilde (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER Francia Contributo UE € 425 000,00 Indirizzo AVENUE DU DOYEN GASTON GIRAUD 191 34000 Montpellier Mostra sulla mappa Regione Occitanie Languedoc-Roussillon Hérault Tipo di attività Research Organisations Contatto amministrativo Valérie Handweiler (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Regno Unito Contributo UE € 1 073 262,00 Indirizzo WELLINGTON SQUARE UNIVERSITY OFFICES OX1 2JD Oxford Mostra sulla mappa Regione South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Linda Pialek (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato DEFYMED Francia Contributo UE € 636 050,00 Indirizzo 9 RUE ALBERT CALMETTE 67200 Strasbourg Mostra sulla mappa Regione Grand Est Alsace Bas-Rhin Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Richard Bou Aoun (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato HUMAN CELL DESIGN Francia Contributo UE € 601 400,00 Indirizzo PLACE PIERRE POTIER CENTRE PIERRE POTIER CANCEROPOLE ENTREE B 1 31000 Toulouse Mostra sulla mappa Regione Occitanie Midi-Pyrénées Haute-Garonne Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Anne-Fabienne Weitsch (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato SARL ENDOCELLS Partecipazione conclusa Francia Contributo UE Nessun dato Indirizzo Boulevard Saint Germain 216 75007 Paris Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Anne-Fabienne Weitsch (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITE CATHOLIQUE DE LOUVAIN Belgio Contributo UE € 1 136 546,00 Indirizzo PLACE DE L UNIVERSITE 1 1348 Louvain La Neuve Mostra sulla mappa Regione Région wallonne Prov. Brabant Wallon Arr. Nivelles Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Pierre Gianello (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
