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Towards a ‘molecular factory’: Processive sequence-selective synthesis with a synthetic molecular machine

Objectif

The aim of this project is to construct a synthetic molecular machine that is capable of performing a complex task, chemical synthesis, far beyond the current state-of-the-art. Our target is to mimic translation, the process through which protein is synthesized on the mRNA template by the ribosome. Although biology uses threaded molecular architectures to transfer chemical information during sequence-specific oligomer and polymer assembly, such processes are yet to be reproduced in artificial small-molecule systems. The successful realization of the project will mark a major breakthrough in the development of artificial molecular machines that can perform real tasks at the molecular level including, ultimately, the synthesis of unnatural sequence specific oligomers and polymers that are not accessible by other routes.

Champ scientifique (EuroSciVoc)

Programme(s)

Thème(s)

Appel à propositions

FP7-PEOPLE-2012-IEF
Voir d’autres projets de cet appel

Régime de financement

MC-IEF - Intra-European Fellowships (IEF)

Coordinateur

THE UNIVERSITY OF MANCHESTER
Contribution de l’UE
€ 231 283,20
Adresse
OXFORD ROAD
M13 9PL Manchester
Royaume-Uni
Région
North West (England) Greater Manchester Manchester
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
Aucune donnée