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Content archived on 2024-05-29

MR-based analysis, Indexing, and Retrieval of brain irON Deposition in Basal ganglia

Objective

The aging in Europe necessitates more effective healthcare solutions especially in neurology, for it is one of the greatest risk factors for certain neurological diseases that impose significant financial and emotional costs to the society, est. 139 billion euros per year, not including the early stages of the disease, the emotional pain of the family, and the loss of experienced people from the workforce. Early detection is essential for alleviation or prevention, but it requires thorough understanding of the chemical changes in the brain. One of the most salient chemical changes regarding these diseases is a large amount of iron accumulation in the basal ganglia (BG) organ of the brain. Thus, it is often claimed that iron could be a potential biomarker for such diseases. This is very appealing because tissues with high iron concentration appear hypo-intense in the T2 contrast of MR images.

To this effect, this project aims at developing:
1) automatic brain MR image analysis methods to detect iron in the BG, and
2) search and retrieval tools to be able to interpret brain MR images by the similarity of iron accumulation in a large population.

These tasks involve multi-disciplinary research from the areas image processing, pattern recognition, databases, and clinical science. Compared with alternatives, MR-based brain iron detection and analysis is cost-effective, fast, and non-invasive. Moreover, we will develop search and retrieval tools to compare patients to correlate the iron-related features with neurological diseases and non-obvious pathologies.

This does not exist today and is revolutionary. With Philips Research Video Processing Group, with its knowledge on image processing, and search and retrieval, and Sabanci University VBALAB, with pattern recognition, machine learning and image analysis knowledge, this project comprises partners with complementary capabilities essential for the success of this project.

Fields of science (EuroSciVoc)

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Keywords

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Topic(s)

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Call for proposal

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FP6-2005-MOBILITY-3
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Funding Scheme

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TOK - Marie Curie actions-Transfer of Knowledge

Coordinator

PHILIPS ELECTRONICS NEDERLAND B.V.
EU contribution
No data
Total cost

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Participants (1)

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