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Contenuto archiviato il 2024-06-18

Novel combination of biopolymers and manufacturing technologies for production of a peripheral nerve implant containing an internal aligned channels array

Obiettivo

Peripheral nerves are basic communication structures guiding motor and sensitive information from CNS to effector or receptor units. Severe nerve injuries include axon bundles section and Schawnn cells destruction, which results in loss of motion control and sensorial perception. After the lesion, cells present in damaged nerves activate spontaneously self-regeneration programs that might facilitate further treatment. Nerve autograft is the “gold standard” surgical intervention that demands autologous tissue extraction and corresponding function loss. The goal of the project is the validation of biomaterials structural plasticity and those compatible manufacturing technologies that will enable the generation of a tubular structure containing an intraluminal microstructure based on an array of aligned channels or fibers. The regenerative properties of this prototype will be also validated in vivo in a sciatic nerve section animal model. This project proposal will take advantage of partners’ experience in the design of medical devices composed of natural and synthetic biomaterials and in scaled-up production mechanization technologies for the generation of the most effective peripheral nerve implant.

Campo scientifico

CORDIS classifica i progetti con EuroSciVoc, una tassonomia multilingue dei campi scientifici, attraverso un processo semi-automatico basato su tecniche NLP.

Invito a presentare proposte

FP7-NMP-2013-SME-7
Vedi altri progetti per questo bando

Coordinatore

FUNDACION TEKNIKER
Contributo UE
€ 663 889,00
Indirizzo
CALLE INAKI GOENAGA 5
20600 Eibar Guipuzcoa
Spagna

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Regione
Noreste País Vasco Gipuzkoa
Tipo di attività
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Costo totale
Nessun dato

Partecipanti (7)