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Ecofriendly synergists for insecticide formulations

Objective

Insect pests cause significant damage to agricultural crops and transmit several important diseases of humans and animals. Chemical insecticides have been used to control insect pests for many decades and remain essential to ensure a supply of affordable food and as part of disease vector control for the foreseeable future. Unfortunately, the world-wide use of synthetic insecticides over many years has led to increased resistance to insecticides and contributed to environmental contamination. One way to reduce insecticide use without compromising control is to use a synergist in combination with an insecticide. Synergists are themselves nontoxic but act by increasing the effectiveness of the insecticides they are used with. They do this by inhibiting the metabolic systems in insects that detoxify insecticides. The goal of this project is to develop ecofriendly synergists for use in formulations with insecticides, both in agriculture and in Public Health, enabling a reduction in the amount of insecticidal active applied, and thereby reducing the adverse effects of these insecticides on beneficial insects such as bees. On the basis of in-depth experimental analyses of the interactions of the known synergist piperonyl butoxide with metabolic enzymes in pest insects, new molecular structures will be designed, synthesized and evaluated on pest and beneficial species using laboratory bioassays and field trials. In addition, the synthesis process to manufacture these synergists will be evaluated with the aim of achieving an industrially and economically feasible process. Finally strategies will be developed that use the novel synergists to enhance the control of insect pests while preserving beneficial insects. As such this research has significant scientific, economic, and social impact as part of sustainable food production and disease control and will enhance the partners’ competitiveness in this important industry by means of global patent and license agreements.

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /agricultural sciences/agriculture, forestry, and fisheries
  • /agricultural sciences/agriculture, forestry, and fisheries/agriculture
  • /agricultural sciences/agriculture, forestry, and fisheries/agriculture/plant breeding/crops
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes

Call for proposal

FP7-SME-2013
See other projects for this call

Funding Scheme

BSG-SME - Research for SMEs

Coordinator

ENDURA SPA
Address
Viale Pietramellara 5
40121 Bologna
Italy
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 522 071
Administrative Contact
Fabrizio Lazzari (Dr.)

Participants (7)

DEWAR CROP PROTECTION LIMITED
United Kingdom
EU contribution
€ 56 916
Address
Drumlanrig Great Saxham
IP29 5JR Bury St Edmunds
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alan Dewar (Dr.)
ANKARA ILERI TEKNOLOJI YATIRIMLARI ANONIM SIRKETI
Turkey
EU contribution
€ 39 618
Address
Ankara Universitesi Teknoloji Gelistirme Bolgesi B Blok Kat 1 No 4
06830 Ankara
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Oktay Gurkan (Prof.)
ROTHAMSTED RESEARCH LIMITED
United Kingdom
EU contribution
€ 64 000
Address
West Common
AL52JQ Harpenden
Activity type
Research Organisations
Administrative Contact
Chris Bass (Dr.)
UNIVERSITA CATTOLICA DEL SACRO CUORE
Italy
EU contribution
€ 24 200
Address
Largo Gemelli 1
20123 Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Cristina Bricchi (Ms.)
AGCHEMACCESS LIMITED
United Kingdom
EU contribution
€ 47 895
Address
Thorpe Road Cedar House 41
NR1 1ES Norfolk
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mone Sharma (Mr.)
VYZKUMNY USTAV VCELARSKY SRO
Czechia
EU contribution
€ 11 400
Address
Dol 94 Maslovice
252 66 Libcice Nad Vltavou
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Dalibor Titera (Dr.)
BABOLNA KORNYEZETBIOLOGIAL KOZPONTKFT
Hungary
EU contribution
€ 120 900
Address
Szallas Utca 6
1107 Budapest
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Janos Szilagyi (Mr.)