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"FLUOR21 : Synthesis, structure and function of fluorinated systems"

Objective

"Organofluorine chemistry has played a significant role in the majority of the spectacular scientific and technological developments of the
past century although this is not widely recognised even by the scientific community. Fluoroorganic molecules are key components in an
ever increasing number of high-value commercially important products particularly in the life science industries. The use of fluorinated
systems in drug discovery programmes has continued to grow and, at present, approximately 30% of new pharmaceutical and
agrochemical systems that enter the market bear fluorine atoms or fluorinated substituents, contributing enormously to the economic wellbeing
of the EU as a whole and the health of its citizens. All useful fluoroorganic systems are ‘man-made’ and the key step in developing
new products and applications involving fluorinated derivatives is the synthesis of carbon-fluorine bonds. We will develop new selective
fluorination processes by using both innovative chemoselective methodology and the emerging field of synthetic biology to provide new
technology platforms beyond the current state-of-the-art. The desire to introduce a fluorine atom into an organic system is often driven by
the fact that the C-F bond imparts unique and highly tuneable control of both geometric and stereoelectronic phenomena within a molecular
structure. The Network’s expertise in handling and analysing fluorinated molecules will allow us to engineer the properties of organic and
biological molecules through the strategic introduction of C-F bonds by molecular editing. A large number of world-leading research
scientists in academia in the various fields of organofluorine chemistry have retired in the recent past and, consequently, if training of ESRs
and support of youthful research groups is not continued, the EU will lose very competitive, highly valuable, high technology, research
expertise that contributes significantly to all chemical, life science and materials sectors."

Field of science

  • /social sciences/economics and business/business and management/commerce
  • /natural sciences/biological sciences/synthetic biology

Call for proposal

FP7-PEOPLE-2013-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITY OF DURHAM
Address
Stockton Road The Palatine Centre
DH1 3LE Durham
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 773 613,28
Administrative Contact
Wendy Harle (Ms.)

Participants (8)

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 610 628,92
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Donal Doolan (Mr.)
Westfälische Wilhelms-Universität Münster
Germany
EU contribution
€ 233 200
Address
Schlossplatz 2
48149 Muenster
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Katharina Steinberg (Dr.)
FREIE UNIVERSITAET BERLIN
Germany
EU contribution
€ 233 200
Address
Kaiserswerther Strasse 16-18
14195 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sandy Leitner
USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.
Czechia
EU contribution
€ 425 920
Address
Flemingovo Nam. 542/2
16610 Praha 6
Activity type
Research Organisations
Administrative Contact
Petr Beier (Dr.)
ASTRAZENECA AB
Sweden
EU contribution
€ 232 272,06
Address
Vastra Maelarhamnen
151 85 Sodertaelje
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Laurent Knerr (Dr.)
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
United Kingdom
EU contribution
€ 290 556,64
Address
North Street 66 College Gate
KY16 9AJ St Andrews
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Trish Starrs (Mrs.)
UNIVERSITAT WIEN
Austria
EU contribution
€ 245 750,56
Address
Universitatsring 1
1010 Wien
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Helmut Schaschl (Dr.)
ALMAC GROUP UK LIMITED
United Kingdom
EU contribution
€ 256 152,17
Address
20 Seagoe Industrial Estate
BT63 5QD Craigavon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Maureen Lennon (Ms.)