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BACterial Hosts for production of Bioactive phenolics from bERRY fruits

Objective

Plants synthesize a staggering variety of secondary metabolites, and this chemodiversity is a poorly used pool of natural molecules with bioactive properties of importance for applications in the pharma and food industries. BacHBerry focusses on phenolic compounds, a large and diverse class of plant metabolites, which are currently in the spotlight due to their claimed beneficial effects in prevention and treatment of chronic diseases, but that also have applications as cosmetics, flavours and food colorants etc. Berries are soft and colourful fruits, with great diversity, high content and unique profiles in phenolic compounds, making them a major source of these high-value metabolites. The BacHBerry project aims to develop a portfolio of sustainable methodologies to mine the potential of the untapped biodiversity of the bioactive phenolic compounds in an extensive collection of berry species. Full exploitation of this unrivalled natural resource requires an integrated and comprehensive effort from bioprospecting in berries using SMART high-throughput screens for the valorisation of phenolic bioactivities aligned with their identification using cutting edge analytics and subsequent elucidation of their biosynthetic pathways. This knowledge will facilitate metabolic engineering of suitable bacterial hosts for high-value phenolics production in scalable fermentation bioprocesses, ultimately serving as commercial production platforms. The consortium comprises a full chain of research and innovation, with 12 research groups, 5 SMEs and a large enterprise, representing 10 countries including partners from ICPC countries Russia, Chile and China, with the capacity to exploit novel bioactivities from berry fruits diversity. BacHBerry develops a pipeline of sustainable and cost-effective processes to facilitate production of added-value berry phenolics with immediate potential for commercialization and consequent socio-economic benefits for the European community and beyond.

Field of science

  • /social sciences/economics and business/economics/sustainable economy
  • /natural sciences/biological sciences/microbiology/bacteriology
  • /agricultural sciences/agriculture, forestry, and fisheries/agriculture/horticulture/fruit
  • /engineering and technology/industrial biotechnology/metabolic engineering

Call for proposal

FP7-KBBE-2013-7-single-stage
See other projects for this call

Funding Scheme

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinator

DANMARKS TEKNISKE UNIVERSITET
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Denmark
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 220 009,22
Administrative Contact
Birte Rasmussen

Participants (18)

INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
Portugal
EU contribution
€ 511 446
Address
Avenida Da Republica Quinta Do Marques
2781-901 Oeiras
Activity type
Research Organisations
Administrative Contact
Elsa Vieira (Dr.)
THE JAMES HUTTON INSTITUTE
United Kingdom
EU contribution
€ 472 110
Address
Errol Road Invergowrie
DD2 5DA Dundee
Activity type
Research Organisations
Administrative Contact
Karen Robb (Mrs.)
JOHN INNES CENTRE
United Kingdom
EU contribution
€ 549 292
Address
Norwich Research Park Colney
NR4 7UH Norwich
Activity type
Research Organisations
Administrative Contact
Mary Anderson (Dr.)
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 441 028,03
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Bjarne Ploumark (Mr.)
RIJKSUNIVERSITEIT GRONINGEN
Netherlands
EU contribution
€ 329 303
Address
Broerstraat 5
9712CP Groningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dick Veldhuis (Dr.)
FORSCHUNGSZENTRUM JULICH GMBH
Germany
EU contribution
€ 578 827,25
Address
Wilhelm Johnen Strasse
52428 Julich
Activity type
Research Organisations
Administrative Contact
Claudia Neuhs
TECHNISCHE UNIVERSITEIT DELFT
Netherlands
EU contribution
€ 549 466
Address
Stevinweg 1
2628 CN Delft
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marcel Ottens (Dr.)
INSTITUTO DE ENGENHARIA MECANICA
Portugal
EU contribution
€ 350 140
Address
Rua Rovisco Pais 1
1049 001 Lisboa
Activity type
Research Organisations
Administrative Contact
Susana Vinga (Dr.)
INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE
France
EU contribution
€ 404 737,80
Address
Domaine De Voluceau Rocquencourt
78153 Le Chesnay Cedex
Activity type
Research Organisations
Administrative Contact
Norina D'arrigo (Ms.)
BIOFACTION KG
Austria
EU contribution
€ 549 250
Address
Kundmanngasse 39/12
1030 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Markus Schmidt (Dr.)
EVOLVA BIOTECH A/S
Denmark
EU contribution
€ 374 444
Address
Lerso Parkalle 42-44
2100 Copenhagen Ø
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jørgen Hansen (Dr.)
CHR. HANSEN A/S
Denmark
EU contribution
€ 131 401,50
Address
Boege Alle 10-12
2970 Hoersholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Finn Okkels (Mr.)
BIOTEMPO - CONSULTORIA EM BIOTECNOLOGIA LDA
Portugal
EU contribution
€ 462 360
Address
Avepark Edificio Spinpark, Zona Industrial Da Gandra
4805 017 Caldas Das Taipas Guimaraes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Isabel Rocha (Ms.)
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Chile
EU contribution
€ 38 775
Address
Avenida Libertador Bernardo O'higgins 340
8331150 Santiago
Activity type
Higher or Secondary Education Establishments
Administrative Contact
María Pilar Bañados (Prof.)
INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES
China
EU contribution
€ 104 429
Address
Nanxincun, Xiangshan 20
100093 Beijing
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Liangsheng Wang (Prof.)
FEDERAL RESEARCH CENTER THE N.I. VAVILOV ALL-RUSSIAN INSTITUTE OF PLANT GENETIC RESOURCES
Russia
EU contribution
€ 62 100
Address
Bolshaya Morskaya Street 42 44
190000 St Petersburg
Activity type
Research Organisations
Administrative Contact
Artem Sorokin (Dr.)
NORFOLK PLANT SCIENCES LIMITED
United Kingdom
EU contribution
€ 63 793
Address
Colney Lane John Innes Centre Norwich Research Park
NR4 7UH Norwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jonathan Jones (Mr.)
CHR. HANSEN NATURAL COLORS AS
Denmark
EU contribution
€ 104 962
Address
Boge Alle 10 12
2970 Horsholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Finn Okkels