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BACterial Hosts for production of Bioactive phenolics from bERRY fruits

Objetivo

Plants synthesize a staggering variety of secondary metabolites, and this chemodiversity is a poorly used pool of natural molecules with bioactive properties of importance for applications in the pharma and food industries. BacHBerry focusses on phenolic compounds, a large and diverse class of plant metabolites, which are currently in the spotlight due to their claimed beneficial effects in prevention and treatment of chronic diseases, but that also have applications as cosmetics, flavours and food colorants etc. Berries are soft and colourful fruits, with great diversity, high content and unique profiles in phenolic compounds, making them a major source of these high-value metabolites. The BacHBerry project aims to develop a portfolio of sustainable methodologies to mine the potential of the untapped biodiversity of the bioactive phenolic compounds in an extensive collection of berry species. Full exploitation of this unrivalled natural resource requires an integrated and comprehensive effort from bioprospecting in berries using SMART high-throughput screens for the valorisation of phenolic bioactivities aligned with their identification using cutting edge analytics and subsequent elucidation of their biosynthetic pathways. This knowledge will facilitate metabolic engineering of suitable bacterial hosts for high-value phenolics production in scalable fermentation bioprocesses, ultimately serving as commercial production platforms. The consortium comprises a full chain of research and innovation, with 12 research groups, 5 SMEs and a large enterprise, representing 10 countries including partners from ICPC countries Russia, Chile and China, with the capacity to exploit novel bioactivities from berry fruits diversity. BacHBerry develops a pipeline of sustainable and cost-effective processes to facilitate production of added-value berry phenolics with immediate potential for commercialization and consequent socio-economic benefits for the European community and beyond.

Convocatoria de propuestas

FP7-KBBE-2013-7-single-stage
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Régimen de financiación

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinador

DANMARKS TEKNISKE UNIVERSITET
Dirección
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Dinamarca
Tipo de actividad
Higher or Secondary Education Establishments
Aportación de la UE
€ 1 220 009,22
Contacto administrativo
Birte Rasmussen

Participantes (18)

INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
Portugal
Aportación de la UE
€ 511 446
Dirección
Avenida Da Republica Quinta Do Marques
2781-901 Oeiras
Tipo de actividad
Research Organisations
Contacto administrativo
Elsa Vieira (Dr.)
THE JAMES HUTTON INSTITUTE
United Kingdom
Aportación de la UE
€ 472 110
Dirección
Errol Road Invergowrie
DD2 5DA Dundee
Tipo de actividad
Research Organisations
Contacto administrativo
Karen Robb (Mrs.)
JOHN INNES CENTRE
United Kingdom
Aportación de la UE
€ 549 292
Dirección
Norwich Research Park Colney
NR4 7UH Norwich
Tipo de actividad
Research Organisations
Contacto administrativo
Mary Anderson (Dr.)
KOBENHAVNS UNIVERSITET
Dinamarca
Aportación de la UE
€ 441 028,03
Dirección
Norregade 10
1165 Kobenhavn
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Bjarne Ploumark (Mr.)
RIJKSUNIVERSITEIT GRONINGEN
Países Bajos
Aportación de la UE
€ 329 303
Dirección
Broerstraat 5
9712CP Groningen
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Dick Veldhuis (Dr.)
FORSCHUNGSZENTRUM JULICH GMBH
Alemania
Aportación de la UE
€ 578 827,25
Dirección
Wilhelm Johnen Strasse
52428 Julich
Tipo de actividad
Research Organisations
Contacto administrativo
Claudia Neuhs
TECHNISCHE UNIVERSITEIT DELFT
Países Bajos
Aportación de la UE
€ 549 466
Dirección
Stevinweg 1
2628 CN Delft
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Marcel Ottens (Dr.)
INSTITUTO DE ENGENHARIA MECANICA
Portugal
Aportación de la UE
€ 350 140
Dirección
Rua Rovisco Pais 1
1049 001 Lisboa
Tipo de actividad
Research Organisations
Contacto administrativo
Susana Vinga (Dr.)
INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE
Francia
Aportación de la UE
€ 404 737,80
Dirección
Domaine De Voluceau Rocquencourt
78153 Le Chesnay Cedex
Tipo de actividad
Research Organisations
Contacto administrativo
Norina D'arrigo (Ms.)
BIOFACTION KG
Austria
Aportación de la UE
€ 549 250
Dirección
Kundmanngasse 39/12
1030 Wien
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Markus Schmidt (Dr.)
EVOLVA BIOTECH A/S
Dinamarca
Aportación de la UE
€ 374 444
Dirección
Lerso Parkalle 42-44
2100 Copenhagen Ø
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Jørgen Hansen (Dr.)
CHR. HANSEN A/S
Dinamarca
Aportación de la UE
€ 131 401,50
Dirección
Boege Alle 10-12
2970 Hoersholm
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Finn Okkels (Mr.)
BIOTEMPO - CONSULTORIA EM BIOTECNOLOGIA LDA
Portugal
Aportación de la UE
€ 462 360
Dirección
Avepark Edificio Spinpark, Zona Industrial Da Gandra
4805 017 Caldas Das Taipas Guimaraes
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Isabel Rocha (Ms.)
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Chile
Aportación de la UE
€ 38 775
Dirección
Avenida Libertador Bernardo O'higgins 340
8331150 Santiago
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
María Pilar Bañados (Prof.)
INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES
China
Aportación de la UE
€ 104 429
Dirección
Nanxincun, Xiangshan 20
100093 Beijing
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Liangsheng Wang (Prof.)
FEDERAL RESEARCH CENTER THE N.I. VAVILOV ALL-RUSSIAN INSTITUTE OF PLANT GENETIC RESOURCES
Rusia
Aportación de la UE
€ 62 100
Dirección
Bolshaya Morskaya Street 42 44
190000 St Petersburg
Tipo de actividad
Research Organisations
Contacto administrativo
Artem Sorokin (Dr.)
NORFOLK PLANT SCIENCES LIMITED
United Kingdom
Aportación de la UE
€ 63 793
Dirección
Colney Lane John Innes Centre Norwich Research Park
NR4 7UH Norwich
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Jonathan Jones (Mr.)
CHR. HANSEN NATURAL COLORS AS
Dinamarca
Aportación de la UE
€ 104 962
Dirección
Boge Alle 10 12
2970 Horsholm
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Finn Okkels