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BACterial Hosts for production of Bioactive phenolics from bERRY fruits

Obiettivo

Plants synthesize a staggering variety of secondary metabolites, and this chemodiversity is a poorly used pool of natural molecules with bioactive properties of importance for applications in the pharma and food industries. BacHBerry focusses on phenolic compounds, a large and diverse class of plant metabolites, which are currently in the spotlight due to their claimed beneficial effects in prevention and treatment of chronic diseases, but that also have applications as cosmetics, flavours and food colorants etc. Berries are soft and colourful fruits, with great diversity, high content and unique profiles in phenolic compounds, making them a major source of these high-value metabolites. The BacHBerry project aims to develop a portfolio of sustainable methodologies to mine the potential of the untapped biodiversity of the bioactive phenolic compounds in an extensive collection of berry species. Full exploitation of this unrivalled natural resource requires an integrated and comprehensive effort from bioprospecting in berries using SMART high-throughput screens for the valorisation of phenolic bioactivities aligned with their identification using cutting edge analytics and subsequent elucidation of their biosynthetic pathways. This knowledge will facilitate metabolic engineering of suitable bacterial hosts for high-value phenolics production in scalable fermentation bioprocesses, ultimately serving as commercial production platforms. The consortium comprises a full chain of research and innovation, with 12 research groups, 5 SMEs and a large enterprise, representing 10 countries including partners from ICPC countries Russia, Chile and China, with the capacity to exploit novel bioactivities from berry fruits diversity. BacHBerry develops a pipeline of sustainable and cost-effective processes to facilitate production of added-value berry phenolics with immediate potential for commercialization and consequent socio-economic benefits for the European community and beyond.

Invito a presentare proposte

FP7-KBBE-2013-7-single-stage
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Meccanismo di finanziamento

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinatore

DANMARKS TEKNISKE UNIVERSITET
Indirizzo
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Danimarca
Tipo di attività
Higher or Secondary Education Establishments
Contributo UE
€ 1 220 009,22
Contatto amministrativo
Birte Rasmussen

Partecipanti (18)

INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
Portogallo
Contributo UE
€ 511 446
Indirizzo
Avenida Da Republica Quinta Do Marques
2781-901 Oeiras
Tipo di attività
Research Organisations
Contatto amministrativo
Elsa Vieira (Dr.)
THE JAMES HUTTON INSTITUTE
United Kingdom
Contributo UE
€ 472 110
Indirizzo
Errol Road Invergowrie
DD2 5DA Dundee
Tipo di attività
Research Organisations
Contatto amministrativo
Karen Robb (Mrs.)
JOHN INNES CENTRE
United Kingdom
Contributo UE
€ 549 292
Indirizzo
Norwich Research Park Colney
NR4 7UH Norwich
Tipo di attività
Research Organisations
Contatto amministrativo
Mary Anderson (Dr.)
KOBENHAVNS UNIVERSITET
Danimarca
Contributo UE
€ 441 028,03
Indirizzo
Norregade 10
1165 Kobenhavn
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Bjarne Ploumark (Mr.)
RIJKSUNIVERSITEIT GRONINGEN
Paesi Bassi
Contributo UE
€ 329 303
Indirizzo
Broerstraat 5
9712CP Groningen
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Dick Veldhuis (Dr.)
FORSCHUNGSZENTRUM JULICH GMBH
Germania
Contributo UE
€ 578 827,25
Indirizzo
Wilhelm Johnen Strasse
52428 Julich
Tipo di attività
Research Organisations
Contatto amministrativo
Claudia Neuhs
TECHNISCHE UNIVERSITEIT DELFT
Paesi Bassi
Contributo UE
€ 549 466
Indirizzo
Stevinweg 1
2628 CN Delft
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Marcel Ottens (Dr.)
INSTITUTO DE ENGENHARIA MECANICA
Portogallo
Contributo UE
€ 350 140
Indirizzo
Rua Rovisco Pais 1
1049 001 Lisboa
Tipo di attività
Research Organisations
Contatto amministrativo
Susana Vinga (Dr.)
INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE
Francia
Contributo UE
€ 404 737,80
Indirizzo
Domaine De Voluceau Rocquencourt
78153 Le Chesnay Cedex
Tipo di attività
Research Organisations
Contatto amministrativo
Norina D'arrigo (Ms.)
BIOFACTION KG
Austria
Contributo UE
€ 549 250
Indirizzo
Kundmanngasse 39/12
1030 Wien
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Markus Schmidt (Dr.)
EVOLVA BIOTECH A/S
Danimarca
Contributo UE
€ 374 444
Indirizzo
Lerso Parkalle 42-44
2100 Copenhagen Ø
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Jørgen Hansen (Dr.)
CHR. HANSEN A/S
Danimarca
Contributo UE
€ 131 401,50
Indirizzo
Boege Alle 10-12
2970 Hoersholm
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Finn Okkels (Mr.)
BIOTEMPO - CONSULTORIA EM BIOTECNOLOGIA LDA
Portogallo
Contributo UE
€ 462 360
Indirizzo
Avepark Edificio Spinpark, Zona Industrial Da Gandra
4805 017 Caldas Das Taipas Guimaraes
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Isabel Rocha (Ms.)
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Cile
Contributo UE
€ 38 775
Indirizzo
Avenida Libertador Bernardo O'higgins 340
8331150 Santiago
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
María Pilar Bañados (Prof.)
INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES
Cina
Contributo UE
€ 104 429
Indirizzo
Nanxincun, Xiangshan 20
100093 Beijing
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Liangsheng Wang (Prof.)
FEDERAL RESEARCH CENTER THE N.I. VAVILOV ALL-RUSSIAN INSTITUTE OF PLANT GENETIC RESOURCES
Russia
Contributo UE
€ 62 100
Indirizzo
Bolshaya Morskaya Street 42 44
190000 St Petersburg
Tipo di attività
Research Organisations
Contatto amministrativo
Artem Sorokin (Dr.)
NORFOLK PLANT SCIENCES LIMITED
United Kingdom
Contributo UE
€ 63 793
Indirizzo
Colney Lane John Innes Centre Norwich Research Park
NR4 7UH Norwich
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Jonathan Jones (Mr.)
CHR. HANSEN NATURAL COLORS AS
Danimarca
Contributo UE
€ 104 962
Indirizzo
Boge Alle 10 12
2970 Horsholm
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Finn Okkels