Objective We aim to commercialise a new, patent-protected concept to measure mechanical properties of biological cells with flow-cytometer-level throughput and establish its standard application in modern drug development and medical diagnostics. Mechanical properties have recently proven to be a physiologically relevant indicator to determine the state, function and type of biological cells. Analysing mechanical parameters provides a novel method to identify physiological or pathological changes. However, mechanical cell properties are currently not accessible for large-scale applications demanding high-throughput. We developed, designed and realised a hydrodynamic cell stretcher, a microfluidic-based device for analysing mechanical cell properties at rates above 100 cells per second and therefore three orders of magnitude faster than other existing methods. In the proposed project, we want to identify, test and validate the most promising applications of hydrodynamic cell stretching in clinical and pharmaceutical research. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-OA-2013-PoC - European Research Council ERC Proof of Concept Call for proposal ERC-2013-PoC See other projects for this call Funding Scheme CSA-SA(POC) - Supporting action (Proof of Concept) Host institution TECHNISCHE UNIVERSITAET DRESDEN EU contribution € 149 549,84 Address HELMHOLTZSTRASSE 10 01069 Dresden Germany See on map Region Sachsen Dresden Dresden, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Friederieke Noack (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all TECHNISCHE UNIVERSITAET DRESDEN Germany EU contribution € 149 549,84 Address HELMHOLTZSTRASSE 10 01069 Dresden See on map Region Sachsen Dresden Dresden, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Friederieke Noack (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
