Providing the right care to the right patient with MyeloDysplastic Syndrome at the right time

Deliverables

Reports on mutational sequencing and epigenetic profiling in various cohorts

Report of ethical, legal, and socio-economical aspects of the elderly low risk MDS population

Completed catalogue of all MDS caregiver cooperative groups, patient support groups and existing documents

Report on the newly defined burden of MDS on HRQoL in MDS and nonMDS cohorts

Report describing the flexible electronic web-based system with evidence-based guidelines for MDS

Yearly MDS Stakeholders Newsletters

Report on the participation in international patient support group meetings.

Report on new COS including patient-reported, disease-specific outcomes

Report of new predictors and prediction functions for impaired HRQoL

Final analyses of models from D1.3 for use in WP5 and WP6

Final report of WP1 and preparation of manuscripts

Validation of a MDS-specific HRQoL questionnaire (QUALMS-1)

A list of HRQoL-adapted treatments for each biologic MDS-subtype

Report on newly generated, high-quality health economic evidence of benefit by personalised MDS care strategies

Periodic report on immunophenotyping in various cohorts

Approved European and International guidelines uploaded at new ELN-linked website

Periodic report on bioinformatic integration of data

Report describing prognostic impact of newly defined individual genetic defects on response to the existing HCI

Report on ms data 100 blood samples with 100 paired BM samples

List of newly identified genetic defects that support development of novel drugs

Report of new specific genetic signatures that support minimal diagnostic criteria recognizing MDS in older individuals

Description of effect estimates for various health-care interventions on HRQoL

Promotion of educational and scientific meetings, pocket cards, posters, flyers, exhibition booth for meetings

A set of measures and prediction functions of HRQoL

Report of early treatment response indicators supporting a targeted use of existing HCI

Scientific, Clinical and Ethics Advisory Board

Appointment of Scientific, Clinical and Ethics Advisory Board

Publications

Moleculaire diagnostiek

Author(s): Jansen J
Published in: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Hematologie, DHC special April, 2018, ISSN 1572-1590
Publisher: Ariez B.V.

Immuunfenotype als voorspeller oor progressie bij MDS

Author(s): van Spronsen et al.
Published in: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Geneeskunde, DHC special April, 2018, ISSN 1572-1590
Publisher: Ariez B.V.

DTUrtle – Differential transcript usage analysis for bulk and single-cell data

Author(s): Tekath T, Dugas M
Published in: 28th International Conference on Intelligent Systems for Molecular Biology (ISMB) 2020, 31 July 2020, 2020, ISSN 2046-1402
Publisher: F1000 Research Ltd

A variant erythroferrone induced by clonal erythropoiesis disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Author(s): Bondu S
Published in: 2019
Publisher: ?

Diagnose en prognose van MDS [In Dutch]

Author(s): vd Loosdrecht AA
Published in: Dutch Hematology Congress 2020, published in: Nederlands Tijdshrift voor Hematologie, 2020, ISSN 1572-1590
Publisher: Ariez B.V.

Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig K, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Stauder R, Siebert U
Published in: 42nd Annual North American Meeting of the Society for Medical Decision Making; published in: Med Decis Making, October 2020, 2020
Publisher: Society for Medical Decision Making

Impact of Treatment with Iron Chelation Therapy in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Author(s): Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Skov-Holm M, Mittelman M, Madry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj-Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van Marrewijk C, Droste J, van Kraaij M, Bowen DT, de Witte TM, Smith A.
Published in: Blood, 130, S1, 2017, Page(s) "#425"
Publisher: American Society of Hematology

Identifying Predictors for Low Health-Related Quality of Life in Patients with Myelodysplastic Syndromes – Research Protocol

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U
Published in: Annual Conference of the German Network for Evidence-based Medicine, 2018
Publisher: German Medical Science Publishing House

Impact of Treatment with Iron Chelation Therapy in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Author(s): Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Skov-Holm M, Mittelman M, Madry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj-Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van Marrewijk C, Droste J, van Kraaij M, Bowen DT, de Witte TM, Smith A.
Published in: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Geneeskunde, 2018
Publisher: Ariez B.V.

Impact of anemia on health-related quality of life depends on age and etiology

Author(s): Wouters HJCM, Van der Klauw MM, de Witte T, Stauder R, Swinkels DW, Wolffenbuttel BHR, Huls G
Published in: Dutch Hematology Congress 2018 (Nederlands Tijdshrift voor Geneeskunde), 2018
Publisher: Ariez B.V.

Impact of Red Blood Cell Transfusion Intensity on Progression-Free Survival in Lower-Risk MDS Patients Included in the European Leukemianet MDS Registry

Author(s): de Swart L, Crouch S, Hoeks M, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Cermak J, Stauder R, Mittelman M, Sanz G, Hellstrom-Lindberg E, Malcovati L, Holm MS, Germing U, Madry K, Almeida AM, Tatic A, Savic A, Gredelj-Šimec N, Guerci Bresler A, Culligan D, Itzykson R, Beyne-Rauzy O, Park S, van Marrewijk C, Blijlevens NMA Bowen DT, de Witte TM.
Published in: Blood, 130, S1, 2017, Page(s) "#1690"
Publisher: American Society of Hematology

Identifying Multinational Cost Data: A Methodological Review and Case Study

Author(s): Thomas Patton, Chu-Mei Hung, Martin Henriksson, Mirjana Huić, Ana Patrícia Marques, Sibylle Puntscher, Đurđa Vukićević, Matteo Ruggeri, Andrea Manca
Published in: EUHEA conference 2018, Maastricht, July 2018, 2018
Publisher: European Health Economics Association

Appreci8: a pipeline for precise variant calling integrating 8 tools

Author(s): Sandmann S, de Graaf AO, Karimi M, van der Reijden BA, Hellström-Lindberg E, Jansen JH, Dugas M
Published in: Haematologica, 102,S2, Jun 26, 2017
Publisher: Ferrata Storti Foundation

Deriving Core Outcomes for Myelodysplastic Syndromes – Health Professionals’ Perspective

Systematic Overview of Patient-Reported Outcomes for Myelodysplastic Syndromes

Author(s): Stojkov I, Rochau U, Conrads-Frank A, Borba HH, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U.
Published in: 17th Biennial European Conference of the Society for Medical Decision Making, 2018
Publisher: Sage Publishing

Developing a Core Outcomes for Myelodysplastic Syndromes – The MDS-RIGHT Health Professional Delphi Survey

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Koinig K.A., Arvandi M, Symeonidis A, Sanz G, Fenaux P, Bowen D, Mittelmann M, Garelius H, Germing U, van Marrewijk C , Cermak J, Hellström-Lindberg E, Smith A, de Witte T, Efficace F, Siebert U, Stauder R.
Published in: 23rd Congress of the European Hematology Association; published in: Haematologica, 103, S1 (June 2018), 2018
Publisher: Ferrata Storti Foundation

Prognostic Value of Early Drop in Platelets in Lower-Risk MDS. A Sub-Study from the European Leukemianet Lower-Risk MDS (EUMDS) Registry

Author(s): Itzykson R, Smith A, Fenaux P, Symeonidis A, Mittelman M, Stauder R, Sanz G, Cermak J, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Germing U, Madry KM, Holm MS, Tatic A, Almeida AM, Savic A, Gredelj-Šimec N, Bowen D, de Witte T.
Published in: Leukemia Research, 55, S1, 2017, Page(s) "#19, S10-11"
Publisher: Pergamon Press Ltd.

Impact of Red Blood Cell Transfusion Rate, Adjusted by Therapeutic interventions, on Progression-Free Survival in Lower-Risk MDS Patients within the European LeukemiaNet MDS Registry

Author(s): de Swart L, Hoeks M, Crouch S, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Stauder R, Sanz G, Mittelman M, Holm MS, Malcovati L, Madry K, Germing U, Savic A, Almeida AM, Guerci Bresler A, Itzykson R, Beyne-Rauzy O, Culligan D, van Marrewijk C, Blijlevens NMA Bowen DT, de Witte TM.
Published in: Haematologica, 103, S1, 2018
Publisher: Ferrata Storti Foundation

Benchmarking Variant Calling Tools for NGS Data

Author(s): Sandmann S, de Graaf AO, Karimi M, van der Reijden BA, Hellström-Lindberg E, Jansen JH, Dugas M
Published in: F1000Research, 6(ISCB Comm J):1353, 2017
Publisher: F1000 Research Ltd

Health-Related Quality of Life Is Substantially Impaired in Lower-Risk MDS When Compared with Reference Populations and Significantly Affects Overall Survival

Author(s): Stauder R, Yu G, Koinig K, Fenaux P, Symeonidis A, Sanz G, Cermak J, Mittelman M, Hellstrom-Lindberg E, Langemeijer S, Holm MS, Madry K, Malcovati L, Tatic A, Germing U, Savic A, Efficace F, Smith A, Bowen D, de Witte T.
Published in: Leukemia Research, 55, S1, 2017, Page(s) "#22, S12"
Publisher: Elsevier

Impact of Red Blood Cell Transfusions on Survival in Lower-Risk MDS Patients Included in the European Leukemianet MDS (EUMDS) Registry

Author(s): de Swart L, Crouch S, Smith A, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Malcovati L, Germing U, Langemeijer S, Holm MS, Mittelman M, Mądry K, Almeida A, Savic A, Itzykson R, Bowen D, de Witte T.
Published in: Leukemia Research, 55, S1, 2017, Page(s) "#280, S160-161"
Publisher: Pergamon Press Ltd.

A Prognostic Classifier Based on Early Platelet Drop in Lower-Risk MDS a Study from the European Leukemianet Lower-Risk MDS (EUMDS) Registry

Author(s): Itzykson R, Crouch S, Smith A, Symeonidis A, Hellstrom-Lindberg E, Sanz G, Cermak J, Stauder R, Malcovati L, Germing U, Mittelman M, Langemeijer S, Madry K, Tatic A, Holm MS, Almeida AM, Savic A, Gredelj-Šimec N, Luño Fernandez E, Culligan D, Guerci Bresler A, van Marrewijk C, Bowen DT, de Witte TM, Fenaux P.
Published in: Blood, 130, S1, 2017, Page(s) "#158"
Publisher: American Society of Hematology

Detecting small structural variants in amplicon-based NGS data - an evaluation of ten algorithms

Author(s): Marius Wöste, Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen, and Martin Dugas
Published in: ISMB abstrats, 2017
Publisher: F1000Research

Developing a Core Outcome Set for Myelodysplastic Syndromes - an International Delphi Survey

Author(s): Stojkov I, Rochau U, Conrads-Frank A, Koinig K.A., Arvandi M, Symeonidis A, Sanz G, Fenaux P, Bowen D, Mittelmann M, Garelius H, Germing U, van Marrewijk C , Cermak J, Hellström-Lindberg E, Smith A, de Witte T, Efficace F, Stauder R, Siebert U.
Published in: 40th Annual North American Meeting of the Society for Medical Decision Making, october 2018, 2018
Publisher: F1000 Research Ltd

Impact van behandeling met ijzerchelatietherapie op patiënten met een laag-risico myelodysplastisch syndroom die deelnemen aan de Europese MDS registratie

Systematic Review of Quality of Life Measurement Instruments and Response Criteria among Patients with Myelodysplastic Syndromes

Author(s): Stojkov I, Rochau U, Borba HH, Jevdjevic M, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U.
Published in: ISPOR 19th Annual European Congress; published in: Value in Health, 19/7 (October 2016), 2016, Page(s) A596, ISSN 1098-3015
Publisher: Blackwell Publishing Inc.

Impact of Treatment with Iron Chelators in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Author(s): Saskia Langemeijer, Louise De Swart, Ge Yu, Alex Smith, Simon Crouch, Tom Johnston, Pierre Fenaux, Argiris Symeonidis, Jaroslav Cermak, Eva Hellstrom-Lindberg, Guillermo Sanz, Reinhard Stauder, Luca Malcovati, Ulrich Germing, Mette Skov Holm, Moshe Mittelman, Krzysztof Madry, Aurelia Tatic, Antonio Almeida, Aleksandar Savic, Sophie Park, Odile Beyne-Rauzy, Raphaël Itzykson, Corine van Marrewijk,
Published in: Blood, 128, 2016, Page(s) 3186
Publisher: American Society of Hematology

Comparison of 1690 MDS Patients from the European LeukemiaNet Registry and Reference Populations - Evidence for a Significant impairment in QoL in MDS and Definition of Predictors of Diminished QoL

Author(s): Reinhard Stauder , Ge Yu , Tim Bagguley , Pierre Fenaux , Argiris Symeonidis , Guillermo Sanz , Jaroslav Cermak , Moshe Mittelman , Eva Hellström-Lindberg , Saskia Langemeijer , Mette Skov Holm , Krzysztof Mądry , Luca Malcovati , Aurelia Tatic , Ulrich Germing , Aleksandar Savic , Corine van Marrewijk , Agnès Guerci-Bresler , Elisa Luño , Jackie Droste , Karin Koinig , Alex Smith , David Bowe
Published in: Hematologica, Volume: 101 Pages: 16-17 Supplement: 1 Meeting Abstract: S13, 2016
Publisher: Ferrata Storti Foundation

Systematic Overview of Response Criteria among Patients with Myelodysplastic Syndromes

Author(s): I Stojkov, U Rochau, HH Borba, M Jevdjevic, K Koinig, M Arvandi, F Efficace, R Stauder, U Siebert
Published in: Society for Medical Decision Making, 38th Annual North American Meeting; published in Value in Health, 19/7, 2016, Page(s) A596 (PSY119), ISSN 1098-3015
Publisher: Blackwell Publishing Inc.

Elevated Labile Plasma Iron Levels (LPI) and Increased Oxidative Stress Are Associated with Red Blood Cell Transfusions in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Subtitle: from the European Leukemianet MDS Registry

Author(s): Marlijn Hoeks, Saskia Langemeijer, Louise De Swart, Tim Bagguley, Corine van Marrewijk, David Bowen, Jaroslav Cermak, Eva Hellstrom-Lindberg, Aurelia Tatic, Argiris Symeonidis, Marian G.J. Van Kraaij, Panagiotis Panagiotidis, Hege Garelius, Dominic J Culligan, Marta Krejci, Jackie Droste, Alexandra Smith, Dorine W. Swinkels and Theo de Witte
Published in: Blood, 128, 2016, Page(s) 4327
Publisher: The American Society of Hematology

Evaluating and Optimizing Variant Calling: A Comparison of Roche 454, Ion Torrent PGM and Illumina NextSeq Sequencing Data

Author(s): Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen and Martin Dugas
Published in: F1000Research, 2015
Publisher: F1000Research

Confident Variant Calling in NGS Data – A Mission Impossible?

Author(s): Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen and Martin Dugas
Published in: F1000Research, 2016
Publisher: F1000Research

Elevated Labile Plasma Iron (LPI) Levels in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Are Associated with Decreased Quality of Life and Reduced Survival

Author(s): Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellström-Lindberg E, Tatic A, Langemeijer S, Culligan DJ, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels DW, and de Witte TM
Published in: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, 132, S1, 2018, Page(s) 4392
Publisher: American Society of Hematology

DTUrtle – an easily accessible Differential Transcript Usage analysis pipeline

Author(s): Tekath T, Dugas M
Published in: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, 14-Aug, 2019, Page(s) 8-1434, ISSN 2046-1402
Publisher: F1000 Research Ltd

New prognostic indicators in MDS identified during the first 10 years of the EUropean LeukemiaNet MDS (EUMDS) Registry

Author(s): de Witte T, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Langemeijer S, Germing U, Holm MS, Mądry K, Tatic A, Almeida AM, Savic A, Gredelj Šimec N, Itzykson R, Culligan D, Kotsianidis I, Ades L, van de Loosdrecht AA, van Marrewijk C, Yu G, Crouch S, Malcovati L, Smith A, on behalf of the EUMDS Registry Participants
Published in: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Publisher: Pergamon Press Ltd.

Can We Diagnose MDS without Bone Marrow Examination? a Proposed EUMDS-Based Non-Invasive Diagnostic Model

Author(s): Oster HS, Shrkihe BA, Crouch S, Smith A, Yu G, Carmi G, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Tatic A, Almeida AM, Savic A, Gredelj-Šimec N, Guerci Bresler A, van Marrewijk C, Bowen DT, de Witte TMM, Mittelman M
Published in: American Society of Hematology 2017 (59th) Annual meeting; published in: Blood, 130, S1, 2017, Page(s) 2975
Publisher: American Society of Hematology

Deriving Core Patient-Reported Outcomes in Patients with Myelodysplastic Syndromes - a Delphi Survey from the European-MDS Registry

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Borba H, Arvandi M, Fenaux P, Symeonidis A, Bowen DT, Mittelman M, van Marrewijk C, de Witte T, Efficace F, Siebert U and Stauder R
Published in: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, 132, S1, 2018, Page(s) 2295
Publisher: American Society of Hematology

Transfusie-afhankelijkheid is geassocieerd met de aanwezigheid van toxische ijzersoorten en slechtere overleving bij patiënten met een laag-risico myelodysplastisch syndroom

Author(s): Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Published in: Nederlandse Vereniging voor Bloedtransfusie - TRIP Symposium 2019; published in: unknown, 2019, Page(s) "#27"
Publisher: unknown

I-CARE for MDS: Development of Guidelines-Based Indicators for Appropriate Care in Adult Patients with Myelodysplastic Syndromes

Author(s): Stojkov K, Silzle T, Stussi G, Schwappach D, Bernhard J, Bowen D, Čermák J, Dinmohamed A, Eeltink C, Eggmann S, Fenaux P, Germing U, Haschke M, Hellstrom-Lindberg E, Heger M, van de Loosdrecht AA, Passweg J, Pfeilstöcker M, Platzbecker U, Malcovati L, Almeida AM, Mittelman M, Morgenthaler C, Steensma D, Santini V, Stauder R, Symeonidis A, Schaer S, Maddox C, de Witte T, Bohlius J, Bonadies N
Published in: American Society of Hematology 2019 (61th) Annual meeting; published in: Blood, 134, S1, 2019, Page(s) 4752
Publisher: American Society of Hematology

Transfusion dependancy is associated with presence of toxic iron species and inferior survival in patients with lower-risk myelodysplastic syndromes

Author(s): Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Published in: International Society of Blood Transfusion (29th) Regional Congress; published in: unknown, 2019
Publisher: unknown

Clonal evolution in MDS

Author(s): Jansen J
Published in: European hematology Association 2017 (22nd) Congress; published in: EHA open access library, 2017
Publisher: European Hematology Association

Consensus on a Core Outcome Set for Myelodysplastic syndromes

Author(s): Rochau U, Stojkov I, Conrads-Frank A, Borba H, Koining K, Arvandi M, van Marrewijk C, Garelius H, Germing U, Symeonidis A, Sanz G, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R.
Published in: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Publisher: Pergamon Press Ltd.

Excess Mortality in Low-Risk MDS Can be Explained By MDS and AML Related Causes of Death

Author(s): Mądry K, Yu G, Lis K, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Couch S, de Witte T, Smith A, on behalf of the EUMDS Registry Participants
Published in: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, 132, S1, 2018, Page(s) 4385
Publisher: American Society of Hematology

Transfusion dependancy is associated with presence of toxic iron species and inferior survival in patients with lower-risk myelodysplastic syndromes

Author(s): Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Published in: European hematology Association 2019 (24th) Congress; published in: EHA open access library, 15-Jun, 2019, Page(s) 267421; S838
Publisher: European Hematology Association

"Appreci8R: an R package for calling variants the ""appreci8""-way"

Author(s): Sandmann S, Dugas M
Published in: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, 12-Aug, 2019, Page(s) 8-1414, ISSN 2046-1402
Publisher: F1000 Research Ltd

Labile Plasma Iron (LPI) Is a Clinical Indicator of Overt Iron Overload in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) from the European Leukemianet MDS Registry

Author(s): de Swart L, Reiniers C, Bagguley T, Bowen D, Cermak J, Hellstrom-Lindberg E, Tatic A, Symeonidis A, Huls G, Panagiotidis P, Garelius H, Culligan D, Krejci M, van Marrewijk C, Droste J, Smith A, Swinkels DW, de Witte T
Published in: American Society of Hematology 2015 (57th) Annual meeting; published in: Blood, 126/23, 2015, Page(s) 2865
Publisher: American Society of Hematology

Longitudinal Changes of Impairments in Health-Related Quality of Life in Lower-Risk MDS Patients: A European Leukemianet Study

Author(s): Stauder R, Yu G, Koinig KA, Culligan D, Fenaux P, Cermak J, Symeonidis A, Bernal T, Hellström-Lindberg E, Mittelman M, Langemeijer S, Holm MS, Mills J, Guerci-Bresler A, van Marrewijk C, Garelius H, Efficace F, Smith A, Bowen D, and de Witte TM
Published in: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, 132, S1, 2018, Page(s) 3097
Publisher: American Society of Hematology

How to “appreci8” Variant Calling in NGS Data

Author(s): Sandmann S, Dugas M
Published in: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, 20-Dec, 2019, Page(s) 8-2128, ISSN 2046-1402
Publisher: F1000 Research Ltd

A Web Application Could Help in MDS Diagnosis and Obviate the Bone Marrow Examination

Author(s): Oster H, Crouch S, Smith A, Yu G, Abu Shrkihe B, Shoham B, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Germing U, Holm MS, Guerci- Bresler A, Culligan D, Laurence S, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M.
Published in: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Publisher: Pergamon Press Ltd.

Prognostic Impact of Transfusions Intensity on Survival and Development of Thrombocytopenia in Newly Diagnosed Lower-Risk MDS Patients Participating in the European Leukemianet EUMDS Registry

Author(s): de Swart L, Johnston T, Smith A, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Malcovati L, Germing U, Huls G, Holm MS, Mittelman M, Madry K, Tatic A, Almeida AM, Savic A, Park S, Beyne-Rauzy O, Itzykson R, van Marrewijk C, Bowen D, de Witte T
Published in: American Society of Hematology 2015 (57th) Annual meeting; published in: Blood, 126/23, 2015, Page(s) 1677
Publisher: American Society of Hematology

Immunophenotypically Aberrant Stem Cells in Myelodysplastic Syndromes: A Biomarker for Leukemic Progression

Author(s): Margot F. Van Spronsen, Theresia M. Westers, Birgit I. Witte, Gert J. Ossenkoppele, Arjan A. Van de Loosdrecht
Published in: American Society of Hematology 2017 (59th) Annual meeting; published in: Blood, 130, S1, 2017, Page(s) 4240
Publisher: American Society of Hematology

AMLVaran: Improvements in user-friendlyness of a human NGS variant assessment system

Author(s): Wünsch C, Dugas M
Published in: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, 30-Jul, 2019, Page(s) 8-1232, ISSN 2046-1402
Publisher: F1000 Research Ltd

MDS Diagnosis: Many Patients May Not Require Bone Marrow Examination

Author(s): Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T and Mittelman M
Published in: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, 132, S1, 2018, Page(s) 4357
Publisher: American Society of Hematology

The anemia-independant effect of Myelodysplastic Syndromes on Health-Related Quality of Life

Author(s): Wouters H, Conrads-Frank A, Koinig KA, Smith A, Yu G, de Witte T, Wolffenbuttel B, Huls G, Siebert U, Stauder R, van der Klauw M
Published in: Virtual 25th Congress of European Hematology Association; published in EHA open access library, 6-dec, 2020, Page(s) 295150; S331
Publisher: European Hematology Association

Assessing the Determinants of Health-Related Quality of Life in patients with Myelodysplastic Syndromes

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig KA, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Siebert U, Stauder R
Published in: Virtual 25th Congress of European Hematology Association; published in EHA open access library, 6-dec, 2020, Page(s) 294713; EP796
Publisher: European Hematology Association

Impact of Erythropoietin Stimulation Agents and Red Blood Cell Transfusion on Health-related Quality of Life in Lower-risk Myelodysplastic Syndrome

Author(s): Garelius H, Smith A, Appleton S, Bowen D, Fenaux P, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Langemeijer S, Holm MS, Itzykson R, Culligan D, Heibl S, Mills J, Bernal T, Kotsianidis I, Ades L, Koinig K, van Marrewijk C, Crouch S, de Witte T, Hellström-Lindberg E
Published in: Virtual 25th Congress of European Hematology Association; published in EHA open access library, 6-Dec, 2020, Page(s) 294733; EP816
Publisher: European Hematology Association

Consensus set of Core Patient-Reported Outcomes for Myelodysplastic Syndromes defined by patients and hematologists - EUMDS Registry group study

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Koinig K, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, Symeonidis A, Chermat F, Garelius H, Bowen D, Mittelman M, Mora E, de Witte T, Efficace F, Siebert U, Stauder R
Published in: Virtual 25th Congress of European Hematology Association; published in EHA open access library, 6-dec, 2020, Page(s) 294734; EP817
Publisher: European Hematology Association

Development of Core Patient-Reported Outcomes in Myelodysplastic Syndromes

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Koinig K, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, de Witte T, Efficace F, Siebert U, and Stauder R
Published in: Society for Medical Decision Making (18th) Biennial European Conference; published in: Med Decis Making, PS1-20 (June) Postponed to 2022, 2020
Publisher: unknown

Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig K, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Stauder R, and Siebert U
Published in: Society for Medical Decision Making (18th) Biennial European Conference, TRA-1-2 (June 2020) Postponed to 2022, 2020
Publisher: unknown

Quality of Life in MDS: Relevance for Patients, Physicians, and Stakeholders

Author(s): Stauder R.
Published in: 2019 Annual Meeting of the German, Austrian and Swiss Societies of Hematology and Medical Oncology, October, 2019
Publisher: unknown

Relevance of patient-reported outcomes (PROs) in patients with cancer at advanced age

Author(s): Stauder R.
Published in: 2019 Annual Meeting of the German, Austrian and Swiss Societies of Hematology and Medical Oncology, October, 2019
Publisher: unknown

Computational flow cytometry: a diagnostic tool in MDS

Author(s): Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, van de Loosdrecht AA
Published in: EMSCO 6th annual meeting, Amsterdam, The Netherlands 21-22 sept 2018, published in: unknown, September, 2018
Publisher: unknown

Artificial intelligence for flow cytometry data analysis in suspected-MDS enables an accurate, objective and fast diagnosis

Author(s): Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Published in: MDS-Foundation (15th) International symposium on MDS; published in: Unknown, May, 2019
Publisher: 1452126

Artificial intelligence improves flow cytometry diagnostics in myelodysplastic syndromes

Author(s): Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Published in: Cancer Research UK - New Directions in Immuno-Oncolog, London UK, Published in : unknown, September, 2019
Publisher: unknown

Computational flow cytometry: a novel diagnostic tool in myelodysplastic syndromes

Author(s): Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, van de Loosdrecht AA
Published in: Dutch Hematology Congress 2019, published in: Nederlands Tijdshrift voor Hematologie, October, 2019, ISSN 1572-1590
Publisher: Ariez B.V.

A Web Application Could Help Diagnose or Exclude MDS, Providing a Noninvasive Alternative to Bone Marrow Examination

Author(s): Oster H, Crouch S, Smith A, Yu G, Ben-Ezra J, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Mądry K, Guerci- Bresler A, Culligan D, Laurence S, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M.
Published in: American Society of Hematology 2019 (61th) Annual meeting; Submitted, 2019
Publisher: -

Analyzing coverage in smMIPs data

Author(s): Sandmann S, de Graaf AO, Jansen JH, Dugas M
Published in: German Conference on Bioinformatics (2020); published in: F1000Research, 29 September 2020, 2020, ISSN 2046-1402
Publisher: F1000 Research Ltd

How to “appreci8” Variant Calling in NGS Data

Author(s): Sandmann S, Dugas M
Published in: German Conference on Bioinformatics, September 2019, 2019
Publisher: ?

Delphi-Survey-Based Development of Core Patient-Reported Outcomes in Myelodysplastic Syndromes

Author(s): Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R
Published in: 42nd Annual North American Meeting of the Society for Medical Decision Making; published in: Med Decis Making, October 2020, 2020
Publisher: Society for Medical Decision Making

Mutatiespectrum en dynamiek van klonale hematopoése bij ouderen met anemie [In Dutch]

Author(s): van Zeventer et al.
Published in: Dutch Hematology Congress 2020, published in: Nederlands Tijdshrift voor Hematologie, 2020, ISSN 1572-1590
Publisher: Ariez B.V.

Distinct bone marrow immunophenotypic features define the splicing factor 3B subunit 1 ( SF3B1 )‐mutant myelodysplastic syndromes subtype

Author(s): Carolien Duetz, Theresia M. Westers, Florentien E. M. in ’t Hout, Eline M. P. Cremers, Canan Alhan, Bianca Venniker‐Punt, Heleen A. Visser‐Wisselaar, Dana A. Chitu, Aniek O. Graaf, Linda Smit, Joop H. Jansen, Arjan A. Loosdrecht
Published in: British Journal of Haematology, 193/4, 2021, Page(s) 798-803, ISSN 0007-1048
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17414

Impact of red blood cell transfusion dose density on progression-free survival in patients with lower-risk myelodysplastic syndromes

Author(s): Louise de Swart, Simon Crouch, Marlijn Hoeks, Alex Smith, Saskia Langemeijer, Pierre Fenaux, Argiris Symeonidis, Jaroslav Cermâk, Eva Hellström-Lindberg, Reinhard Stauder, Guillermo Sanz, Moshe Mittelman, Mette Skov Holm, Luca Malcovati, Krzysztof Mądry, Ulrich Germing, Aurelia Tatic, Aleksandar Savic, Antonio Medina Almeida, Njetocka Gredelj-Simec, Agnes Guerci-Bresler, Odile Beyne-Rauzy, Domi
Published in: Haematologica, 105/3, 2020, Page(s) 632-639, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212217

CopyDetective: Detection threshold–aware copy number variant calling in whole-exome sequencing data

Author(s): Sarah Sandmann, Marius Wöste, Aniek O de Graaf, Birgit Burkhardt, Joop H Jansen, Martin Dugas
Published in: GigaScience, 9/11, 2020, Page(s) giaa118, ISSN 2047-217X
Publisher: Oxford University Press and the Beijing Genomics Institute
DOI: 10.1093/gigascience/giaa118

Multicenter Next-Generation Sequencing Studies between Theory and Practice

Author(s): Sarah Sandmann, Aniek O. de Graaf, Magnus Tobiasson, Olivier Kosmider, María Abáigar, Emmanuelle Clappier, Anna Gallì, Bert A. van der Reijden, Luca Malcovati, Pierre Fenaux, María Díez-Campelo, Michaela Fontenay, Eva Hellström-Lindberg, Joop H. Jansen, Martin Dugas
Published in: The Journal of Molecular Diagnostics, 23/3, 2021, Page(s) 347-357, ISSN 1525-1578
Publisher: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2020.12.001

Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes

Author(s): Louise de Swart, Chloé Reiniers, Timothy Bagguley, Corine van Marrewijk, David Bowen, Eva Hellström-Lindberg, Aurelia Tatic, Argiris Symeonidis, Gerwin Huls, Jaroslav Cermak, Arjan A. van de Loosdrecht, Hege Garelius, Dominic Culligan, Mac Macheta, Michail Spanoudakis, Panagiotis Panagiotidis, Marta Krejci, Nicole Blijlevens, Saskia Langemeijer, Jackie Droste, Dorine W. Swinkels, Alex Smith, The
Published in: Haematologica, 103/1, 2017, Page(s) 69-79, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2017.171884

GLM-based optimization of NGS data analysis: A case study of Roche 454, Ion Torrent PGM and Illumina NextSeq sequencing data

Author(s): Sarah Sandmann, Aniek O. de Graaf, Bert A. van der Reijden, Joop H. Jansen, Martin Dugas
Published in: PLOS ONE, 12/2, 2017, Page(s) e0171983, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0171983

BBCAnalyzer: a visual approach to facilitate variant calling

Author(s): Sarah Sandmann, Aniek O. de Graaf, Martin Dugas
Published in: BMC Bioinformatics, 18/1, 2017, Page(s) 133: 1-6, ISSN 1471-2105
Publisher: BioMed Central
DOI: 10.1186/s12859-017-1549-4

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

Author(s): Theo de Witte, David Bowen, Marie Robin, Luca Malcovati, Dietger Niederwieser, Ibrahim Yakoub-Agha, Ghulam J. Mufti, Pierre Fenaux, Guillermo Sanz, Rodrigo Martino, Emilio Paolo Alessandrino, Francesco Onida, Argiris Symeonidis, Jakob Passweg, Guido Kobbe, Arnold Ganser, Uwe Platzbecker, Jürgen Finke, Michel van Gelder, Arjan A. van de Loosdrecht, Per Ljungman, Reinhard Stauder, Liisa Volin, H. J
Published in: Blood, 129/13, 2017, Page(s) 1753-1762, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood-2016-06-724500

Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT

Author(s): Gerbrig Berger, Leonie I. Kroeze, Theresia N. Koorenhof-Scheele, Aniek O. de Graaf, Kenichi Yoshida, Hiroo Ueno, Yuichi Shiraishi, Satoru Miyano, Eva van den Berg, Hein Schepers, Bert A. van der Reijden, Seishi Ogawa, Edo Vellenga, Joop H. Jansen
Published in: Blood, 131/16, 2018, Page(s) 1846-1857, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood-2017-09-805879

Author(s): Reinhard Stauder, Ge Yu, Karin A. Koinig, Tim Bagguley, Pierre Fenaux, Argiris Symeonidis, Guillermo Sanz, Jaroslav Cermak, Moshe Mittelman, Eva Hellström-Lindberg, Saskia Langemeijer, Mette Skov Holm, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Ulrich Germing, Aleksandar Savic, Corine van Marrewijk, Agnès Guerci-Bresler, Elisa Luño, Jackie Droste, Fabio Efficace, Alex Smith, David Bowen,
Published in: Leukemia, 32/6, 2018, Page(s) 1380-1392, ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-018-0089-x

Clonal evolution in myelodysplastic syndromes

Author(s): Pedro da Silva-Coelho, Leonie I. Kroeze, Kenichi Yoshida, Theresia N. Koorenhof-Scheele, Ruth Knops, Louis T. van de Locht, Aniek O. de Graaf, Marion Massop, Sarah Sandmann, Martin Dugas, Marian J. Stevens-Kroef, Jaroslav Cermak, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Theo de Witte, Nicole M. A. Blijlevens, Petra Muus, Gerwin Huls, Bert A. van der Reijden, Seishi Ogawa, Joo
Published in: Nature Communications, 8, 2017, Page(s) 15099, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/ncomms15099

Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data

Author(s): Sarah Sandmann, Aniek O. de Graaf, Mohsen Karimi, Bert A. van der Reijden, Eva Hellström-Lindberg, Joop H. Jansen, Martin Dugas
Published in: Scientific Reports, 7, 2017, Page(s) 43169, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep43169

VIPER: a web application for rapid expert review of variant calls

Author(s): Marius Wöste, Martin Dugas
Published in: Bioinformatics, 34/11, 2018, Page(s) 1928-1929, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/bty022

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes

Author(s): Raphael Itzykson, Simon Crouch, Erica Travaglino, Alex Smith, Argiris Symeonidis, Eva Hellström-Lindberg, Guillermo Sanz, Jaroslav Čermák, Reinhard Stauder, Chiara Elena, Ulrich Germing, Moshe Mittelman, Saskia Langemeijer, Krzysztof Mądry, Aurelia Tatic, Mette Skov Holm, Antonio Medina Almeida, Aleksandar Savic, Njetočka Gredelj Šimec, Elisa Luño, Dominic Culligan, Agnes Guerci-Bresler, Lu
Published in: Blood Advances, 2/16, 2018, Page(s) 2079-2089, ISSN 2473-9529
Publisher: American Society of Hematology
DOI: 10.1182/bloodadvances.2018020495

Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome

Author(s): H. K. G. Garelius, W. T. Johnston, A. G. Smith, S. Park, L. de Swart, P. Fenaux, A. Symeonidis, G. Sanz, J. Čermák, R. Stauder, L. Malcovati, M. Mittelman, A. A. van de Loosdrecht, C. J. van Marrewijk, D. Bowen, S. Crouch, T. J. M. de Witte, E. Hellström-Lindberg
Published in: Journal of Internal Medicine, 281/3, 2016, Page(s) 284-299, ISSN 0954-6820
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/joim.12579

appreci8: a pipeline for precise variant calling integrating 8 tools

Author(s): Sarah Sandmann, Mohsen Karimi, Aniek O de Graaf, Christian Rohde, Stefanie Göllner, Julian Varghese, Jan Ernsting, Gunilla Walldin, Bert A van der Reijden, Carsten Müller-Tidow, Luca Malcovati, Eva Hellström-Lindberg, Joop H Jansen, Martin Dugas
Published in: Bioinformatics, 34/24, 2018, Page(s) 4205-4212, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/bty518

ODM Data Analysis—A tool for the automatic validation, monitoring and generation of generic descriptive statistics of patient data

Author(s): Tobias Johannes Brix, Philipp Bruland, Saad Sarfraz, Jan Ernsting, Philipp Neuhaus, Michael Storck, Justin Doods, Sonja Ständer, Martin Dugas
Published in: PLOS ONE, 13/6, 2018, Page(s) e0199242, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0199242

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Author(s): Marlijn Hoeks, Ge Yu, Saskia Langemeijer, Simon Crouch, Louise de Swart, Pierre Fenaux, Argiris Symeonidis, Jaroslav Čermák, Eva Hellström-Lindberg, Guillermo Sanz, Reinhard Stauder, Mette Skov Holm, Moshe Mittelman, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Antonio Medina Almeida, Ulrich Germing, Aleksandar Savic, Njetočka Gredelj Šimec, Dominic Culligan, Raphael Itzykson, Agnes Guerc
Published in: Haematologica, Haematologica 2019 Jul 5; Epub ahead of print, 2019, Page(s) haematol.2018.212332, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212332

Impact of red blood cell transfusion dose density on progression-free survival in lower-risk myelodysplastic syndromes patients

Author(s): Louise de Swart, Simon Crouch, Marlijn Hoeks, Alex Smith, Saskia Langemeijer, Pierre Fenaux, Argiris Symeonidis, Jaroslav Čermák, Eva Hellström-Lindberg, Reinhard Stauder, Guillermo Sanz, Moshe Mittelman, Mette Skov Holm, Luca Malcovati, Krzysztof Mądry, Ulrich Germing, Aurelia Tatic, Aleksandar Savic, Antonio Medina Almeida, Njetočka Gredelj-Šimec, Agnes Guerci-Bresler, Odile Beyne-Rauzy, D
Published in: Haematologica, Haematologica 2019 Jun 6; Epub ahead of print, 2019, Page(s) haematol.2018.212217, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212217

Computational analysis of flow cytometry data in hematological malignancies

Author(s): Carolien Duetz, Costa Bachas, Theresia M. Westers, Arjan A. van de Loosdrecht
Published in: Current Opinion in Oncology, 32 (2020) [2019 Epub ahead of print], 2019, Page(s) 1, ISSN 1040-8746
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/cco.0000000000000607

Association of anemia with health-related quality of life and survival: a large population-based cohort study

Author(s): Hanneke J.C.M. Wouters, Melanie M. van der Klauw, Theo de Witte, Reinhard Stauder, Dorine W. Swinkels, Bruce H.R. Wolffenbuttel, Gerwin Huls
Published in: Haematologica, 104/3, 2019, Page(s) 468-476, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.195552

Multidisciplinary care in the hematology clinic: Implementation of geriatric oncology

Author(s): Valentin Goede, Reinhard Stauder
Published in: Journal of Geriatric Oncology, 10/3, 2019, Page(s) 497-503, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2018.09.003

Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals

Author(s): Isabelle A. van Zeventer, Aniek O. de Graaf, Hanneke JCM Wouters, Bert A. Van der Reijden, Melanie van der Klauw, Theo M de Witte, Marianne A. Jonker, Luca Malcovati, Joop H Jansen, Geert Huls
Published in: Blood, 135(14), 2020, Page(s) 1161-1170, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2019004362

AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting

Author(s): Christian Wünsch, Henrik Banck, Carsten Müller-Tidow, Martin Dugas
Published in: BMC Medical Genomics, 13/1, 2020, ISSN 1755-8794
Publisher: BioMed Central
DOI: 10.1186/s12920-020-0668-3

Myelodysplastic syndromes: moving towards personalized management

Author(s): Eva Hellström-Lindberg, Magnus Tobiasson, Peter Greenberg
Published in: Haematologica, 105/7, 2020, Page(s) 1765-1779, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.248955

Development of a core outcome set for myelodysplastic syndromes – a Delphi study from the EUMDS Registry Group

Author(s): Ursula Rochau, Igor Stojkov, Annette Conrads‐Frank, Helena H. Borba, Karin A. Koinig, Marjan Arvandi, Corine Marrewijk, Hege Garelius, Ulrich Germing, Argiris Symeonidis, Guillermo F. Sanz, Pierre Fenaux, Theo Witte, Fabio Efficace, Uwe Siebert, Reinhard Stauder
Published in: British Journal of Haematology, 2020 May 14. [Epub ahead of print], 2020, ISSN 0007-1048
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjh.16654

Clinical and Lab Parameters may rule out and assist in the Diagnosis of MDS

Author(s): Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T and Mittelman M
Published in: Leukemia, (under peer review), 2020, ISSN 0887-6924
Publisher: Nature Publishing Group

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome

Author(s): Marlijn Hoeks, Tim Bagguley, Corine van Marrewijk, Alex Smith, David Bowen, Dominic Culligan, Seye Kolade, Argiris Symeonidis, Hege Garelius, Michail Spanoudakis, Saskia Langemeijer, Rian Roelofs, Erwin Wiegerinck, Aurelia Tatic, Sally Killick, Panagiotis Panagiotidis, Oana Stanca, Eva Hellström-Lindberg, Jaroslav Cermak, Melanie van der Klauw, Hanneke Wouters, Marian van Kraaij, Nicole Blijleven
Published in: Leukemia, Sep 18. [Epub ahead of print], 2020, Page(s) 2021 Jun;35(6):1745-1750 [jounal version], ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-020-01022-2

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

Author(s): Theo De Witte, Luca Malcovati, Pierre Fenaux, David Bowen, Argiris Symeonidis, Moshe Mittelman, Reinhard Stauder, Guillermo Sanz, Jaroslav Čermák, Saskia Langemeijer, Eva Hellström-Lindberg, Ulrich Germing, Mette Skov Holm, Krzysztof Mądry, Aurelia Tatic, António Medina Almeida, Aleksandar Savic, Inga Mandac Rogulj, Raphael Itzykson, Marlijn Hoeks, Hege Gravdahl Garelius, Dominic Culligan, Io
Published in: Haematologica, 105/11, 2020, Page(s) 2516-2523, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.266817

Comparison of Open-access Databases for Clinical Variant Interpretation in Cancer: A Case Study of MDS/AML

Author(s): HENRIK BANCK, MARTIN DUGAS, CARSTEN MÜLLER-TIDOW, SARAH SANDMANN
Published in: Cancer Genomics - Proteomics, 18/2, 2021, Page(s) 157-166, ISSN 1109-6535
Publisher: International Institute of Anticancer Research
DOI: 10.21873/cgp.20250

Computational analysis of flow cytometry data in hematological malignancies: future clinical practice?

Author(s): Carolien Duetz, Costa Bachas, Theresia M. Westers, Arjan A. van de Loosdrecht
Published in: Current Opinion in Oncology, 32/2, 2020, Page(s) 162-169, ISSN 1040-8746
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/cco.0000000000000607

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Author(s): Marlijn Hoeks, Ge Yu, Saskia Langemeijer, Simon Crouch, Louise de Swart, Pierre Fenaux, Argiris Symeonidis, Jaroslav Čermák, Eva Hellström-Lindberg, Guillermo Sanz, Reinhard Stauder, Mette Skov Holm, Moshe Mittelman, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Antonio Medina Almeida, Ulrich Germing, Aleksandar Savic, Njetočka Gredelj Šimec, Dominic Culligan, Raphael Itzykson, Agnes Guerc
Published in: Haematologica, 105/3, 2020, Page(s) 640-651, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212332

Development of a core outcome set for myelodysplastic syndromes – a Delphi study from the EUMDS Registry Group

Author(s): Ursula Rochau, Igor Stojkov, Annette Conrads‐Frank, Helena H. Borba, Karin A. Koinig, Marjan Arvandi, Corine Marrewijk, Hege Garelius, Ulrich Germing, Argiris Symeonidis, Guillermo F. Sanz, Pierre Fenaux, Theo Witte, Fabio Efficace, Uwe Siebert, Reinhard Stauder
Published in: British Journal of Haematology, 191/3, 2020, Page(s) 405-417, ISSN 0007-1048
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjh.16654

Myelodysplastisch syndroom

Author(s): van de Loostdrecht AA
Published in: Nederlands Tijdschrift voor Hematologie [In Dutch], DHC special April, 2020, ISSN 1572-1590
Publisher: Ariez B.V.

Mutatiespectrum en dynamiek van klonale hematopoëse bij ouderen met anemie

Author(s): van Zeventer, I
Published in: Nederlands Tijdschrift voor Hematologie [In Dutch], DHC special April, 2020, ISSN 1572-1590
Publisher: Ariez B.V.

IJzerchelatie bij laag-risico myelodysplsie

Author(s): Langemeijer S (& Hoeks M)
Published in: Nederlands Tijdschrift voor Hematologie, DHC special April 2018, 2018, Page(s) 18-19, ISSN 1572-1590
Publisher: Ariez B.V.

MDS: de juiste zorg op het juiste moment - MDS is een complexe en relatief zeldzame ziekte, maar het aantal patiënten groeit. Het project MDS-RIGHT heeft tot doel de zorg voor MDS-patiënten te verbeteren. Op welke manier?

Author(s): de Witte, T (Gal M)
Published in: HEMATON [In Dutch], Magazine 16 Winter 2017, 2017, Page(s) 28-31
Publisher: Stichting Hematon

Immuunfenotype als voorspeller voor pregressie bij MDS

Author(s): van Spronsen M
Published in: Nederlands Tijdschrift voor Hematologie [In Dutch], DHC special April, 2018, Page(s) 11, ISSN 1572-1590
Publisher: Ariez B.V.

Anemie en kwaliteit van leven

Author(s): Wouters HJCM
Published in: Nederlands Tijdschrift voor Hematologie [In Dutch], DHC special April, 2018, Page(s) 12, ISSN 1572-1590
Publisher: Ariez B.V.

Moleculaire Diagnostiek

Author(s): Jansen J
Published in: Nederlands Tijdschrift voor Hematologie [In Dutch], DHC special April, 2018, Page(s) 54, ISSN 1572-1590
Publisher: Ariez B.V.

Patiënten met laagrisico-MDS: met het oog op ijzergerelateerde problematiek

Author(s): de Swart L
Published in: Medidact – Hematlogie [In Dutch], Augustus vol. 4 / nr. 4, 2019, Page(s) 18
Publisher: unknown

De nieuwste ontwikkelingen op het gebied van ijzerstapeling bij myelodysplastisch syndroom

Author(s): Hoeks M, Zwaginga JJ
Published in: Hematologie Actueel [In Dutch], Jaargang 19 | nr. 2 | september 2019 [In Dutch], 2019
Publisher: Academic Pharmaceutical Productions bv

Red blood cell transfusions in hemato-oncological patients - Don't iron out the consequences

Author(s): Marlijn Hoeks, MD
Published in: 3 November, 2020, ISBN 978-94-6421-027-9
Publisher: Ipskamp Printing

The mutational landscape and microenvironment in Myelodysplastic Syndromes with deletion of chromosome 5q

Author(s): Christian Scharenberg, MD
Published in: 2 March, 2018, ISBN 978-91-7676-985-0
Publisher: Karolinska Institutet

Registry studies on myelodysplastic syndrome and secondary acute myeloid leukemia

Author(s): Hege Garelius, MD
Published in: 4 May, 2018, ISBN 978-91-629-0488-3
Publisher: BrandFactory

Patients with lower-risk myelodysplastic syndromes: in scope of iron related complications

Author(s): Louise de Swart
Published in: 12 June, 2019, ISBN 978-94-6380-330-4
Publisher: ProefschriftMaken.nl

The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]

Author(s): Robin M, de Witte T. Myelodysplastic Syndromes. In: Carreras E, Dufour C, Mohty M, Kröger N, editors.
Published in: The EBMT Handbook, 7th ed., Chapter 73, 2019
Publisher: Springer