Providing the right care to the right patient with MyeloDysplastic Syndrome at the right time

Livrables

Updated patient handbooks of the national MDS patient groups
Operational project specific MDS-RIGHT website
Yearly electronic updates of the evidence-based therapeutic guidelines

Yearly electronic updates of the evidencebased therapeutic guidelines

Discussion platforms and a common website for stakeholder interaction
Yearly updates of MDS website

Report of two meetings on state-of-the-art in the field of MDS
Report on the endorsement of the new evidence-based guidelines for MDS patients
Final dataset incorporating data generated from WP2, WP3 & WP4
Periodic report on mutational sequencing and epigenetic profiling in various cohorts

Reports on mutational sequencing and epigenetic profiling in various cohorts

Report of ethical, legal, and socio-economical aspects of the elderly low risk MDS population
Completed catalogue of all MDS caregiver cooperative groups, patient support groups and existing documents
Report on the newly defined burden of MDS on HRQoL in MDS and nonMDS cohorts
Report describing the flexible electronic web-based system with evidence-based guidelines for MDS
Yearly MDS Stakeholders Newsletters
Report on the participation in international patient support group meetings.
Report on new COS including patient-reported, disease-specific outcomes
Report of new predictors and prediction functions for impaired HRQoL
Final analyses of models from D1.3 for use in WP5 and WP6
Final report of WP1 and preparation of manuscripts
Validation of a MDS-specific HRQoL questionnaire (QUALMS-1)
A list of HRQoL-adapted treatments for each biologic MDS-subtype
Report on newly generated, high-quality health economic evidence of benefit by personalised MDS care strategies
Periodic report on immunophenotyping in various cohorts
Approved European and International guidelines uploaded at new ELN-linked website
Periodic report on bioinformatic integration of data
Report describing prognostic impact of newly defined individual genetic defects on response to the existing HCI
Report on ms data 100 blood samples with 100 paired BM samples

List of newly identified genetic defects that support development of novel drugs
Report of new specific genetic signatures that support minimal diagnostic criteria recognizing MDS in older individuals
Description of effect estimates for various health-care interventions on HRQoL
Promotion of educational and scientific meetings, pocket cards, posters, flyers, exhibition booth for meetings
A set of measures and prediction functions of HRQoL
Report of early treatment response indicators supporting a targeted use of existing HCI

Scientific, Clinical and Ethics Advisory Board

Appointment of Scientific, Clinical and Ethics Advisory Board

Publications

Moleculaire diagnostiek

Auteurs: Jansen J
Publié dans: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Hematologie, Numéro DHC special April, 2018, ISSN 1572-1590
Éditeur: Ariez B.V.

Immuunfenotype als voorspeller oor progressie bij MDS

Auteurs: van Spronsen et al.
Publié dans: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Geneeskunde, Numéro DHC special April, 2018, ISSN 1572-1590
Éditeur: Ariez B.V.

DTUrtle – Differential transcript usage analysis for bulk and single-cell data

Auteurs: Tekath T, Dugas M
Publié dans: 28th International Conference on Intelligent Systems for Molecular Biology (ISMB) 2020, Numéro 31 July 2020, 2020, ISSN 2046-1402
Éditeur: F1000 Research Ltd

A variant erythroferrone induced by clonal erythropoiesis disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Auteurs: Bondu S
Publié dans: 2019
Éditeur: ?

A variant erythroferrone induced by clonal erythropoiesis disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Auteurs: Bondu S
Publié dans: 2020
Éditeur: ?

Longitudinal Study on Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig KA, Schomaker M, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Cermak J, Sanz GF, Hellstrom Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci Bresler A, Culligan DJ, Kotsianidis I, Sanhes L, Mills J, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Siebert U, Stauder R
Publié dans: American Society of Hematology 2020 (62nd) Annual meeting; published in: Blood, Numéro December 2020, 2020
Éditeur: American Society of Hematology

Diagnose en prognose van MDS [In Dutch]

Auteurs: vd Loosdrecht AA
Publié dans: Dutch Hematology Congress 2020, published in: Nederlands Tijdshrift voor Hematologie, 2020, ISSN 1572-1590
Éditeur: Ariez B.V.

Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig K, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Stauder R, Siebert U
Publié dans: 42nd Annual North American Meeting of the Society for Medical Decision Making; published in: Med Decis Making, Numéro October 2020, 2020
Éditeur: Society for Medical Decision Making

Impact of Treatment with Iron Chelation Therapy in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Auteurs: Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Skov-Holm M, Mittelman M, Madry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj-Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van Marrewijk C, Droste J, van Kraaij M, Bowen DT, de Witte TM, Smith A.
Publié dans: Blood, Numéro 130, S1, 2017, Page(s) "#425"
Éditeur: American Society of Hematology

Identifying Predictors for Low Health-Related Quality of Life in Patients with Myelodysplastic Syndromes – Research Protocol

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U
Publié dans: Annual Conference of the German Network for Evidence-based Medicine, 2018
Éditeur: German Medical Science Publishing House

Impact of Treatment with Iron Chelation Therapy in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Auteurs: Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Skov-Holm M, Mittelman M, Madry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj-Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van Marrewijk C, Droste J, van Kraaij M, Bowen DT, de Witte TM, Smith A.
Publié dans: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Geneeskunde, 2018
Éditeur: Ariez B.V.

Impact of anemia on health-related quality of life depends on age and etiology

Auteurs: Wouters HJCM, Van der Klauw MM, de Witte T, Stauder R, Swinkels DW, Wolffenbuttel BHR, Huls G
Publié dans: Dutch Hematology Congress 2018 (Nederlands Tijdshrift voor Geneeskunde), 2018
Éditeur: Ariez B.V.

Impact of Red Blood Cell Transfusion Intensity on Progression-Free Survival in Lower-Risk MDS Patients Included in the European Leukemianet MDS Registry

Auteurs: de Swart L, Crouch S, Hoeks M, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Cermak J, Stauder R, Mittelman M, Sanz G, Hellstrom-Lindberg E, Malcovati L, Holm MS, Germing U, Madry K, Almeida AM, Tatic A, Savic A, Gredelj-Šimec N, Guerci Bresler A, Culligan D, Itzykson R, Beyne-Rauzy O, Park S, van Marrewijk C, Blijlevens NMA Bowen DT, de Witte TM.
Publié dans: Blood, Numéro 130, S1, 2017, Page(s) "#1690"
Éditeur: American Society of Hematology

Identifying Multinational Cost Data: A Methodological Review and Case Study

Auteurs: Thomas Patton, Chu-Mei Hung, Martin Henriksson, Mirjana Huić, Ana Patrícia Marques, Sibylle Puntscher, Đurđa Vukićević, Matteo Ruggeri, Andrea Manca
Publié dans: EUHEA conference 2018, Maastricht, Numéro July 2018, 2018
Éditeur: European Health Economics Association

Appreci8: a pipeline for precise variant calling integrating 8 tools

Auteurs: Sandmann S, de Graaf AO, Karimi M, van der Reijden BA, Hellström-Lindberg E, Jansen JH, Dugas M
Publié dans: Haematologica, Numéro 102,S2, Jun 26, 2017
Éditeur: Ferrata Storti Foundation

Deriving Core Outcomes for Myelodysplastic Syndromes – Health Professionals’ Perspective

Systematic Overview of Patient-Reported Outcomes for Myelodysplastic Syndromes

Auteurs: Stojkov I, Rochau U, Conrads-Frank A, Borba HH, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U.
Publié dans: 17th Biennial European Conference of the Society for Medical Decision Making, 2018
Éditeur: Sage Publishing

Developing a Core Outcomes for Myelodysplastic Syndromes – The MDS-RIGHT Health Professional Delphi Survey

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Koinig K.A., Arvandi M, Symeonidis A, Sanz G, Fenaux P, Bowen D, Mittelmann M, Garelius H, Germing U, van Marrewijk C , Cermak J, Hellström-Lindberg E, Smith A, de Witte T, Efficace F, Siebert U, Stauder R.
Publié dans: 23rd Congress of the European Hematology Association; published in: Haematologica, Numéro 103, S1 (June 2018), 2018
Éditeur: Ferrata Storti Foundation

Prognostic Value of Early Drop in Platelets in Lower-Risk MDS. A Sub-Study from the European Leukemianet Lower-Risk MDS (EUMDS) Registry

Auteurs: Itzykson R, Smith A, Fenaux P, Symeonidis A, Mittelman M, Stauder R, Sanz G, Cermak J, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Germing U, Madry KM, Holm MS, Tatic A, Almeida AM, Savic A, Gredelj-Šimec N, Bowen D, de Witte T.
Publié dans: Leukemia Research, Numéro 55, S1, 2017, Page(s) "#19, S10-11"
Éditeur: Pergamon Press Ltd.

Impact of Red Blood Cell Transfusion Rate, Adjusted by Therapeutic interventions, on Progression-Free Survival in Lower-Risk MDS Patients within the European LeukemiaNet MDS Registry

Auteurs: de Swart L, Hoeks M, Crouch S, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Stauder R, Sanz G, Mittelman M, Holm MS, Malcovati L, Madry K, Germing U, Savic A, Almeida AM, Guerci Bresler A, Itzykson R, Beyne-Rauzy O, Culligan D, van Marrewijk C, Blijlevens NMA Bowen DT, de Witte TM.
Publié dans: Haematologica, Numéro 103, S1, 2018
Éditeur: Ferrata Storti Foundation

Benchmarking Variant Calling Tools for NGS Data

Auteurs: Sandmann S, de Graaf AO, Karimi M, van der Reijden BA, Hellström-Lindberg E, Jansen JH, Dugas M
Publié dans: F1000Research, Numéro 6(ISCB Comm J):1353, 2017
Éditeur: F1000 Research Ltd

Health-Related Quality of Life Is Substantially Impaired in Lower-Risk MDS When Compared with Reference Populations and Significantly Affects Overall Survival

Auteurs: Stauder R, Yu G, Koinig K, Fenaux P, Symeonidis A, Sanz G, Cermak J, Mittelman M, Hellstrom-Lindberg E, Langemeijer S, Holm MS, Madry K, Malcovati L, Tatic A, Germing U, Savic A, Efficace F, Smith A, Bowen D, de Witte T.
Publié dans: Leukemia Research, Numéro 55, S1, 2017, Page(s) "#22, S12"
Éditeur: Elsevier

Impact of Red Blood Cell Transfusions on Survival in Lower-Risk MDS Patients Included in the European Leukemianet MDS (EUMDS) Registry

Auteurs: de Swart L, Crouch S, Smith A, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Malcovati L, Germing U, Langemeijer S, Holm MS, Mittelman M, Mądry K, Almeida A, Savic A, Itzykson R, Bowen D, de Witte T.
Publié dans: Leukemia Research, Numéro 55, S1, 2017, Page(s) "#280, S160-161"
Éditeur: Pergamon Press Ltd.

A Prognostic Classifier Based on Early Platelet Drop in Lower-Risk MDS a Study from the European Leukemianet Lower-Risk MDS (EUMDS) Registry

Auteurs: Itzykson R, Crouch S, Smith A, Symeonidis A, Hellstrom-Lindberg E, Sanz G, Cermak J, Stauder R, Malcovati L, Germing U, Mittelman M, Langemeijer S, Madry K, Tatic A, Holm MS, Almeida AM, Savic A, Gredelj-Šimec N, Luño Fernandez E, Culligan D, Guerci Bresler A, van Marrewijk C, Bowen DT, de Witte TM, Fenaux P.
Publié dans: Blood, Numéro 130, S1, 2017, Page(s) "#158"
Éditeur: American Society of Hematology

Detecting small structural variants in amplicon-based NGS data - an evaluation of ten algorithms

Auteurs: Marius Wöste, Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen, and Martin Dugas
Publié dans: ISMB abstrats, 2017
Éditeur: F1000Research

Developing a Core Outcome Set for Myelodysplastic Syndromes - an International Delphi Survey

Auteurs: Stojkov I, Rochau U, Conrads-Frank A, Koinig K.A., Arvandi M, Symeonidis A, Sanz G, Fenaux P, Bowen D, Mittelmann M, Garelius H, Germing U, van Marrewijk C , Cermak J, Hellström-Lindberg E, Smith A, de Witte T, Efficace F, Stauder R, Siebert U.
Publié dans: 40th Annual North American Meeting of the Society for Medical Decision Making, Numéro october 2018, 2018
Éditeur: F1000 Research Ltd

Impact van behandeling met ijzerchelatietherapie op patiënten met een laag-risico myelodysplastisch syndroom die deelnemen aan de Europese MDS registratie

Systematic Review of Quality of Life Measurement Instruments and Response Criteria among Patients with Myelodysplastic Syndromes

Auteurs: Stojkov I, Rochau U, Borba HH, Jevdjevic M, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U.
Publié dans: ISPOR 19th Annual European Congress; published in: Value in Health, Numéro 19/7 (October 2016), 2016, Page(s) A596, ISSN 1098-3015
Éditeur: Blackwell Publishing Inc.

Impact of Treatment with Iron Chelators in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Auteurs: Saskia Langemeijer, Louise De Swart, Ge Yu, Alex Smith, Simon Crouch, Tom Johnston, Pierre Fenaux, Argiris Symeonidis, Jaroslav Cermak, Eva Hellstrom-Lindberg, Guillermo Sanz, Reinhard Stauder, Luca Malcovati, Ulrich Germing, Mette Skov Holm, Moshe Mittelman, Krzysztof Madry, Aurelia Tatic, Antonio Almeida, Aleksandar Savic, Sophie Park, Odile Beyne-Rauzy, Raphaël Itzykson, Corine van Marrewijk,
Publié dans: Blood, Numéro 128, 2016, Page(s) 3186
Éditeur: American Society of Hematology

Comparison of 1690 MDS Patients from the European LeukemiaNet Registry and Reference Populations - Evidence for a Significant impairment in QoL in MDS and Definition of Predictors of Diminished QoL

Auteurs: Reinhard Stauder , Ge Yu , Tim Bagguley , Pierre Fenaux , Argiris Symeonidis , Guillermo Sanz , Jaroslav Cermak , Moshe Mittelman , Eva Hellström-Lindberg , Saskia Langemeijer , Mette Skov Holm , Krzysztof Mądry , Luca Malcovati , Aurelia Tatic , Ulrich Germing , Aleksandar Savic , Corine van Marrewijk , Agnès Guerci-Bresler , Elisa Luño , Jackie Droste , Karin Koinig , Alex Smith , David Bowe
Publié dans: Hematologica, Numéro Volume: 101 Pages: 16-17 Supplement: 1 Meeting Abstract: S13, 2016
Éditeur: Ferrata Storti Foundation

Systematic Overview of Response Criteria among Patients with Myelodysplastic Syndromes

Auteurs: I Stojkov, U Rochau, HH Borba, M Jevdjevic, K Koinig, M Arvandi, F Efficace, R Stauder, U Siebert
Publié dans: Society for Medical Decision Making, 38th Annual North American Meeting; published in Value in Health, Numéro 19/7, 2016, Page(s) A596 (PSY119), ISSN 1098-3015
Éditeur: Blackwell Publishing Inc.

Elevated Labile Plasma Iron Levels (LPI) and Increased Oxidative Stress Are Associated with Red Blood Cell Transfusions in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Subtitle: from the European Leukemianet MDS Registry

Auteurs: Marlijn Hoeks, Saskia Langemeijer, Louise De Swart, Tim Bagguley, Corine van Marrewijk, David Bowen, Jaroslav Cermak, Eva Hellstrom-Lindberg, Aurelia Tatic, Argiris Symeonidis, Marian G.J. Van Kraaij, Panagiotis Panagiotidis, Hege Garelius, Dominic J Culligan, Marta Krejci, Jackie Droste, Alexandra Smith, Dorine W. Swinkels and Theo de Witte
Publié dans: Blood, Numéro 128, 2016, Page(s) 4327
Éditeur: The American Society of Hematology

Evaluating and Optimizing Variant Calling: A Comparison of Roche 454, Ion Torrent PGM and Illumina NextSeq Sequencing Data

Auteurs: Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen and Martin Dugas
Publié dans: F1000Research, 2015
Éditeur: F1000Research

Confident Variant Calling in NGS Data – A Mission Impossible?

Auteurs: Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen and Martin Dugas
Publié dans: F1000Research, 2016
Éditeur: F1000Research

Elevated Labile Plasma Iron (LPI) Levels in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Are Associated with Decreased Quality of Life and Reduced Survival

Auteurs: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellström-Lindberg E, Tatic A, Langemeijer S, Culligan DJ, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels DW, and de Witte TM
Publié dans: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Numéro 132, S1, 2018, Page(s) 4392
Éditeur: American Society of Hematology

DTUrtle – an easily accessible Differential Transcript Usage analysis pipeline

Auteurs: Tekath T, Dugas M
Publié dans: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Numéro 14-Aug, 2019, Page(s) 8-1434, ISSN 2046-1402
Éditeur: F1000 Research Ltd

New prognostic indicators in MDS identified during the first 10 years of the EUropean LeukemiaNet MDS (EUMDS) Registry

Auteurs: de Witte T, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Langemeijer S, Germing U, Holm MS, Mądry K, Tatic A, Almeida AM, Savic A, Gredelj Šimec N, Itzykson R, Culligan D, Kotsianidis I, Ades L, van de Loosdrecht AA, van Marrewijk C, Yu G, Crouch S, Malcovati L, Smith A, on behalf of the EUMDS Registry Participants
Publié dans: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Éditeur: Pergamon Press Ltd.

Can We Diagnose MDS without Bone Marrow Examination? a Proposed EUMDS-Based Non-Invasive Diagnostic Model

Auteurs: Oster HS, Shrkihe BA, Crouch S, Smith A, Yu G, Carmi G, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Tatic A, Almeida AM, Savic A, Gredelj-Šimec N, Guerci Bresler A, van Marrewijk C, Bowen DT, de Witte TMM, Mittelman M
Publié dans: American Society of Hematology 2017 (59th) Annual meeting; published in: Blood, Numéro 130, S1, 2017, Page(s) 2975
Éditeur: American Society of Hematology

Deriving Core Patient-Reported Outcomes in Patients with Myelodysplastic Syndromes - a Delphi Survey from the European-MDS Registry

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Borba H, Arvandi M, Fenaux P, Symeonidis A, Bowen DT, Mittelman M, van Marrewijk C, de Witte T, Efficace F, Siebert U and Stauder R
Publié dans: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Numéro 132, S1, 2018, Page(s) 2295
Éditeur: American Society of Hematology

Transfusie-afhankelijkheid is geassocieerd met de aanwezigheid van toxische ijzersoorten en slechtere overleving bij patiënten met een laag-risico myelodysplastisch syndroom

Auteurs: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Publié dans: Nederlandse Vereniging voor Bloedtransfusie - TRIP Symposium 2019; published in: unknown, 2019, Page(s) "#27"
Éditeur: unknown

I-CARE for MDS: Development of Guidelines-Based Indicators for Appropriate Care in Adult Patients with Myelodysplastic Syndromes

Auteurs: Stojkov K, Silzle T, Stussi G, Schwappach D, Bernhard J, Bowen D, Čermák J, Dinmohamed A, Eeltink C, Eggmann S, Fenaux P, Germing U, Haschke M, Hellstrom-Lindberg E, Heger M, van de Loosdrecht AA, Passweg J, Pfeilstöcker M, Platzbecker U, Malcovati L, Almeida AM, Mittelman M, Morgenthaler C, Steensma D, Santini V, Stauder R, Symeonidis A, Schaer S, Maddox C, de Witte T, Bohlius J, Bonadies N
Publié dans: American Society of Hematology 2019 (61th) Annual meeting; published in: Blood, Numéro 134, S1, 2019, Page(s) 4752
Éditeur: American Society of Hematology

Transfusion dependancy is associated with presence of toxic iron species and inferior survival in patients with lower-risk myelodysplastic syndromes

Auteurs: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Publié dans: International Society of Blood Transfusion (29th) Regional Congress; published in: unknown, 2019
Éditeur: unknown

Clonal evolution in MDS

Auteurs: Jansen J
Publié dans: European hematology Association 2017 (22nd) Congress; published in: EHA open access library, 2017
Éditeur: European Hematology Association

Consensus on a Core Outcome Set for Myelodysplastic syndromes

Auteurs: Rochau U, Stojkov I, Conrads-Frank A, Borba H, Koining K, Arvandi M, van Marrewijk C, Garelius H, Germing U, Symeonidis A, Sanz G, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R.
Publié dans: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Éditeur: Pergamon Press Ltd.

Excess Mortality in Low-Risk MDS Can be Explained By MDS and AML Related Causes of Death

Auteurs: Mądry K, Yu G, Lis K, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Couch S, de Witte T, Smith A, on behalf of the EUMDS Registry Participants
Publié dans: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Numéro 132, S1, 2018, Page(s) 4385
Éditeur: American Society of Hematology

Transfusion dependancy is associated with presence of toxic iron species and inferior survival in patients with lower-risk myelodysplastic syndromes

Auteurs: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Publié dans: European hematology Association 2019 (24th) Congress; published in: EHA open access library, Numéro 15-Jun, 2019, Page(s) 267421; S838
Éditeur: European Hematology Association

"Appreci8R: an R package for calling variants the ""appreci8""-way"

Auteurs: Sandmann S, Dugas M
Publié dans: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Numéro 12-Aug, 2019, Page(s) 8-1414, ISSN 2046-1402
Éditeur: F1000 Research Ltd

Labile Plasma Iron (LPI) Is a Clinical Indicator of Overt Iron Overload in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) from the European Leukemianet MDS Registry

Auteurs: de Swart L, Reiniers C, Bagguley T, Bowen D, Cermak J, Hellstrom-Lindberg E, Tatic A, Symeonidis A, Huls G, Panagiotidis P, Garelius H, Culligan D, Krejci M, van Marrewijk C, Droste J, Smith A, Swinkels DW, de Witte T
Publié dans: American Society of Hematology 2015 (57th) Annual meeting; published in: Blood, Numéro 126/23, 2015, Page(s) 2865
Éditeur: American Society of Hematology

Longitudinal Changes of Impairments in Health-Related Quality of Life in Lower-Risk MDS Patients: A European Leukemianet Study

Auteurs: Stauder R, Yu G, Koinig KA, Culligan D, Fenaux P, Cermak J, Symeonidis A, Bernal T, Hellström-Lindberg E, Mittelman M, Langemeijer S, Holm MS, Mills J, Guerci-Bresler A, van Marrewijk C, Garelius H, Efficace F, Smith A, Bowen D, and de Witte TM
Publié dans: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Numéro 132, S1, 2018, Page(s) 3097
Éditeur: American Society of Hematology

How to “appreci8” Variant Calling in NGS Data

Auteurs: Sandmann S, Dugas M
Publié dans: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Numéro 20-Dec, 2019, Page(s) 8-2128, ISSN 2046-1402
Éditeur: F1000 Research Ltd

A Web Application Could Help in MDS Diagnosis and Obviate the Bone Marrow Examination

Auteurs: Oster H, Crouch S, Smith A, Yu G, Abu Shrkihe B, Shoham B, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Germing U, Holm MS, Guerci- Bresler A, Culligan D, Laurence S, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M.
Publié dans: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Éditeur: Pergamon Press Ltd.

Prognostic Impact of Transfusions Intensity on Survival and Development of Thrombocytopenia in Newly Diagnosed Lower-Risk MDS Patients Participating in the European Leukemianet EUMDS Registry

Auteurs: de Swart L, Johnston T, Smith A, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Malcovati L, Germing U, Huls G, Holm MS, Mittelman M, Madry K, Tatic A, Almeida AM, Savic A, Park S, Beyne-Rauzy O, Itzykson R, van Marrewijk C, Bowen D, de Witte T
Publié dans: American Society of Hematology 2015 (57th) Annual meeting; published in: Blood, Numéro 126/23, 2015, Page(s) 1677
Éditeur: American Society of Hematology

Immunophenotypically Aberrant Stem Cells in Myelodysplastic Syndromes: A Biomarker for Leukemic Progression

Auteurs: Margot F. Van Spronsen, Theresia M. Westers, Birgit I. Witte, Gert J. Ossenkoppele, Arjan A. Van de Loosdrecht
Publié dans: American Society of Hematology 2017 (59th) Annual meeting; published in: Blood, Numéro 130, S1, 2017, Page(s) 4240
Éditeur: American Society of Hematology

AMLVaran: Improvements in user-friendlyness of a human NGS variant assessment system

Auteurs: Wünsch C, Dugas M
Publié dans: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Numéro 30-Jul, 2019, Page(s) 8-1232, ISSN 2046-1402
Éditeur: F1000 Research Ltd

MDS Diagnosis: Many Patients May Not Require Bone Marrow Examination

Auteurs: Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T and Mittelman M
Publié dans: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Numéro 132, S1, 2018, Page(s) 4357
Éditeur: American Society of Hematology

The anemia-independant effect of Myelodysplastic Syndromes on Health-Related Quality of Life

Auteurs: Wouters H, Conrads-Frank A, Koinig KA, Smith A, Yu G, de Witte T, Wolffenbuttel B, Huls G, Siebert U, Stauder R, van der Klauw M
Publié dans: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Numéro 6-dec, 2020, Page(s) 295150; S331
Éditeur: European Hematology Association

Assessing the Determinants of Health-Related Quality of Life in patients with Myelodysplastic Syndromes

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig KA, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Siebert U, Stauder R
Publié dans: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Numéro 6-dec, 2020, Page(s) 294713; EP796
Éditeur: European Hematology Association

Impact of Erythropoietin Stimulation Agents and Red Blood Cell Transfusion on Health-related Quality of Life in Lower-risk Myelodysplastic Syndrome

Auteurs: Garelius H, Smith A, Appleton S, Bowen D, Fenaux P, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Langemeijer S, Holm MS, Itzykson R, Culligan D, Heibl S, Mills J, Bernal T, Kotsianidis I, Ades L, Koinig K, van Marrewijk C, Crouch S, de Witte T, Hellström-Lindberg E
Publié dans: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Numéro 6-Dec, 2020, Page(s) 294733; EP816
Éditeur: European Hematology Association

Consensus set of Core Patient-Reported Outcomes for Myelodysplastic Syndromes defined by patients and hematologists - EUMDS Registry group study

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Koinig K, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, Symeonidis A, Chermat F, Garelius H, Bowen D, Mittelman M, Mora E, de Witte T, Efficace F, Siebert U, Stauder R
Publié dans: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Numéro 6-dec, 2020, Page(s) 294734; EP817
Éditeur: European Hematology Association

Development of Core Patient-Reported Outcomes in Myelodysplastic Syndromes

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Koinig K, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, de Witte T, Efficace F, Siebert U, and Stauder R
Publié dans: Society for Medical Decision Making (18th) Biennial European Conference; published in: Med Decis Making, Numéro PS1-20 (June) Postponed to 2022, 2020
Éditeur: unknown

Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig K, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Stauder R, and Siebert U
Publié dans: Society for Medical Decision Making (18th) Biennial European Conference, Numéro TRA-1-2 (June 2020) Postponed to 2022, 2020
Éditeur: unknown

Quality of Life in MDS: Relevance for Patients, Physicians, and Stakeholders

Auteurs: Stauder R.
Publié dans: 2019 Annual Meeting of the German, Austrian and Swiss Societies of Hematology and Medical Oncology, Numéro October, 2019
Éditeur: unknown

Relevance of patient-reported outcomes (PROs) in patients with cancer at advanced age

Auteurs: Stauder R.
Publié dans: 2019 Annual Meeting of the German, Austrian and Swiss Societies of Hematology and Medical Oncology, Numéro October, 2019
Éditeur: unknown

Computational flow cytometry: a diagnostic tool in MDS

Auteurs: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, van de Loosdrecht AA
Publié dans: EMSCO 6th annual meeting, Amsterdam, The Netherlands 21-22 sept 2018, published in: unknown, Numéro September, 2018
Éditeur: unknown

Artificial intelligence for flow cytometry data analysis in suspected-MDS enables an accurate, objective and fast diagnosis

Auteurs: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Publié dans: MDS-Foundation (15th) International symposium on MDS; published in: Unknown, Numéro May, 2019
Éditeur: 1452126

Artificial intelligence improves flow cytometry diagnostics in myelodysplastic syndromes

Auteurs: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Publié dans: Cancer Research UK - New Directions in Immuno-Oncolog, London UK, Published in : unknown, Numéro September, 2019
Éditeur: unknown

Computational flow cytometry: a novel diagnostic tool in myelodysplastic syndromes

Auteurs: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, van de Loosdrecht AA
Publié dans: Dutch Hematology Congress 2019, published in: Nederlands Tijdshrift voor Hematologie, Numéro October, 2019, ISSN 1572-1590
Éditeur: Ariez B.V.

Mutation Profiles Identify Distinct Clusters of Lower Risk Myelodysplastic Syndromes with Unique Clinical and Biological Features and Clinical Endpoints

Auteurs: Malcovati L , Crouch S, de Graaf AO, Sandmann S, Tobiasson M, Kosmider O, van der Reijden BA, Painter D , van de Loosdrecht AA , Symeonidis A, Cermak J, Clappier E, Preudhomme C, Staudern R, Mittelman M, Germing U, Bowen D, Fenaux P, van Marrewijk C, Smith A, Dugas M, Hellstrom Lindberg E, de Witte TM , Fontenay M, Jansen J
Publié dans: American Society of Hematology 2020 (62nd) Annual meeting; published in: Blood, Numéro 136/S1 (5 November 2020), 2020, Page(s) 29
Éditeur: American Society of Hematology

A Web Application Could Help Diagnose or Exclude MDS, Providing a Noninvasive Alternative to Bone Marrow Examination

Auteurs: Oster H, Crouch S, Smith A, Yu G, Ben-Ezra J, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Mądry K, Guerci- Bresler A, Culligan D, Laurence S, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M.
Publié dans: American Society of Hematology 2019 (61th) Annual meeting; Submitted, 2019
Éditeur: -

Analyzing coverage in smMIPs data

Auteurs: Sandmann S, de Graaf AO, Jansen JH, Dugas M
Publié dans: German Conference on Bioinformatics (2020); published in: F1000Research, Numéro 29 September 2020, 2020, ISSN 2046-1402
Éditeur: F1000 Research Ltd

How to “appreci8” Variant Calling in NGS Data

Auteurs: Sandmann S, Dugas M
Publié dans: German Conference on Bioinformatics, Numéro September 2019, 2019
Éditeur: ?

Delphi-Survey-Based Development of Core Patient-Reported Outcomes in Myelodysplastic Syndromes

Auteurs: Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R
Publié dans: 42nd Annual North American Meeting of the Society for Medical Decision Making; published in: Med Decis Making, Numéro October 2020, 2020
Éditeur: Society for Medical Decision Making

Mutatiespectrum en dynamiek van klonale hematopoése bij ouderen met anemie [In Dutch]

Auteurs: van Zeventer et al.
Publié dans: Dutch Hematology Congress 2020, published in: Nederlands Tijdshrift voor Hematologie, 2020, ISSN 1572-1590
Éditeur: Ariez B.V.

Distinct bone marrow immunophenotypic features define the splicing factor 3B subunit 1 ( SF3B1 )‐mutant myelodysplastic syndromes subtype

Auteurs: Carolien Duetz, Theresia M. Westers, Florentien E. M. in ’t Hout, Eline M. P. Cremers, Canan Alhan, Bianca Venniker‐Punt, Heleen A. Visser‐Wisselaar, Dana A. Chitu, Aniek O. Graaf, Linda Smit, Joop H. Jansen, Arjan A. Loosdrecht
Publié dans: British Journal of Haematology, Numéro 193/4, 2021, Page(s) 798-803, ISSN 0007-1048
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17414

Impact of red blood cell transfusion dose density on progression-free survival in patients with lower-risk myelodysplastic syndromes

Auteurs: Louise de Swart, Simon Crouch, Marlijn Hoeks, Alex Smith, Saskia Langemeijer, Pierre Fenaux, Argiris Symeonidis, Jaroslav Cermâk, Eva Hellström-Lindberg, Reinhard Stauder, Guillermo Sanz, Moshe Mittelman, Mette Skov Holm, Luca Malcovati, Krzysztof Mądry, Ulrich Germing, Aurelia Tatic, Aleksandar Savic, Antonio Medina Almeida, Njetocka Gredelj-Simec, Agnes Guerci-Bresler, Odile Beyne-Rauzy, Domi
Publié dans: Haematologica, Numéro 105/3, 2020, Page(s) 632-639, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212217

CopyDetective: Detection threshold–aware copy number variant calling in whole-exome sequencing data

Auteurs: Sarah Sandmann, Marius Wöste, Aniek O de Graaf, Birgit Burkhardt, Joop H Jansen, Martin Dugas
Publié dans: GigaScience, Numéro 9/11, 2020, Page(s) giaa118, ISSN 2047-217X
Éditeur: Oxford University Press and the Beijing Genomics Institute
DOI: 10.1093/gigascience/giaa118

Multicenter Next-Generation Sequencing Studies between Theory and Practice

Auteurs: Sarah Sandmann, Aniek O. de Graaf, Magnus Tobiasson, Olivier Kosmider, María Abáigar, Emmanuelle Clappier, Anna Gallì, Bert A. van der Reijden, Luca Malcovati, Pierre Fenaux, María Díez-Campelo, Michaela Fontenay, Eva Hellström-Lindberg, Joop H. Jansen, Martin Dugas
Publié dans: The Journal of Molecular Diagnostics, Numéro 23/3, 2021, Page(s) 347-357, ISSN 1525-1578
Éditeur: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2020.12.001

Immunophenotypic aberrant hematopoietic stem cells in myelodysplastic syndromes: a biomarker for leukemic progression

Auteurs: van Spronsen M, Hanekamp D, Westers T, Jansen J, Lissenberg-Witte B, Cloos J, Schuurhuis G, van de Loosdrecht AA
Publié dans: Blood, Numéro (under peer-review), 2021, ISSN 0006-4971
Éditeur: American Society of Hematology

Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes.

Auteurs: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Publié dans: Cytometry A., Numéro (under peer-review - conditionally accepted with minor changes), 2021, ISSN 1552-4922
Éditeur: John Wiley & Sons Ltd.

Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes

Auteurs: Louise de Swart, Chloé Reiniers, Timothy Bagguley, Corine van Marrewijk, David Bowen, Eva Hellström-Lindberg, Aurelia Tatic, Argiris Symeonidis, Gerwin Huls, Jaroslav Cermak, Arjan A. van de Loosdrecht, Hege Garelius, Dominic Culligan, Mac Macheta, Michail Spanoudakis, Panagiotis Panagiotidis, Marta Krejci, Nicole Blijlevens, Saskia Langemeijer, Jackie Droste, Dorine W. Swinkels, Alex Smith, The
Publié dans: Haematologica, Numéro 103/1, 2017, Page(s) 69-79, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2017.171884

GLM-based optimization of NGS data analysis: A case study of Roche 454, Ion Torrent PGM and Illumina NextSeq sequencing data

Auteurs: Sarah Sandmann, Aniek O. de Graaf, Bert A. van der Reijden, Joop H. Jansen, Martin Dugas
Publié dans: PLOS ONE, Numéro 12/2, 2017, Page(s) e0171983, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0171983

BBCAnalyzer: a visual approach to facilitate variant calling

Auteurs: Sarah Sandmann, Aniek O. de Graaf, Martin Dugas
Publié dans: BMC Bioinformatics, Numéro 18/1, 2017, Page(s) 133: 1-6, ISSN 1471-2105
Éditeur: BioMed Central
DOI: 10.1186/s12859-017-1549-4

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

Auteurs: Theo de Witte, David Bowen, Marie Robin, Luca Malcovati, Dietger Niederwieser, Ibrahim Yakoub-Agha, Ghulam J. Mufti, Pierre Fenaux, Guillermo Sanz, Rodrigo Martino, Emilio Paolo Alessandrino, Francesco Onida, Argiris Symeonidis, Jakob Passweg, Guido Kobbe, Arnold Ganser, Uwe Platzbecker, Jürgen Finke, Michel van Gelder, Arjan A. van de Loosdrecht, Per Ljungman, Reinhard Stauder, Liisa Volin, H. J
Publié dans: Blood, Numéro 129/13, 2017, Page(s) 1753-1762, ISSN 0006-4971
Éditeur: American Society of Hematology
DOI: 10.1182/blood-2016-06-724500

Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT

Auteurs: Gerbrig Berger, Leonie I. Kroeze, Theresia N. Koorenhof-Scheele, Aniek O. de Graaf, Kenichi Yoshida, Hiroo Ueno, Yuichi Shiraishi, Satoru Miyano, Eva van den Berg, Hein Schepers, Bert A. van der Reijden, Seishi Ogawa, Edo Vellenga, Joop H. Jansen
Publié dans: Blood, Numéro 131/16, 2018, Page(s) 1846-1857, ISSN 0006-4971
Éditeur: American Society of Hematology
DOI: 10.1182/blood-2017-09-805879

Auteurs: Reinhard Stauder, Ge Yu, Karin A. Koinig, Tim Bagguley, Pierre Fenaux, Argiris Symeonidis, Guillermo Sanz, Jaroslav Cermak, Moshe Mittelman, Eva Hellström-Lindberg, Saskia Langemeijer, Mette Skov Holm, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Ulrich Germing, Aleksandar Savic, Corine van Marrewijk, Agnès Guerci-Bresler, Elisa Luño, Jackie Droste, Fabio Efficace, Alex Smith, David Bowen,
Publié dans: Leukemia, Numéro 32/6, 2018, Page(s) 1380-1392, ISSN 0887-6924
Éditeur: Nature Publishing Group
DOI: 10.1038/s41375-018-0089-x

Clonal evolution in myelodysplastic syndromes

Auteurs: Pedro da Silva-Coelho, Leonie I. Kroeze, Kenichi Yoshida, Theresia N. Koorenhof-Scheele, Ruth Knops, Louis T. van de Locht, Aniek O. de Graaf, Marion Massop, Sarah Sandmann, Martin Dugas, Marian J. Stevens-Kroef, Jaroslav Cermak, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Theo de Witte, Nicole M. A. Blijlevens, Petra Muus, Gerwin Huls, Bert A. van der Reijden, Seishi Ogawa, Joo
Publié dans: Nature Communications, Numéro 8, 2017, Page(s) 15099, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/ncomms15099

Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data

Auteurs: Sarah Sandmann, Aniek O. de Graaf, Mohsen Karimi, Bert A. van der Reijden, Eva Hellström-Lindberg, Joop H. Jansen, Martin Dugas
Publié dans: Scientific Reports, Numéro 7, 2017, Page(s) 43169, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/srep43169

VIPER: a web application for rapid expert review of variant calls

Auteurs: Marius Wöste, Martin Dugas
Publié dans: Bioinformatics, Numéro 34/11, 2018, Page(s) 1928-1929, ISSN 1367-4803
Éditeur: Oxford University Press
DOI: 10.1093/bioinformatics/bty022

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes

Auteurs: Raphael Itzykson, Simon Crouch, Erica Travaglino, Alex Smith, Argiris Symeonidis, Eva Hellström-Lindberg, Guillermo Sanz, Jaroslav Čermák, Reinhard Stauder, Chiara Elena, Ulrich Germing, Moshe Mittelman, Saskia Langemeijer, Krzysztof Mądry, Aurelia Tatic, Mette Skov Holm, Antonio Medina Almeida, Aleksandar Savic, Njetočka Gredelj Šimec, Elisa Luño, Dominic Culligan, Agnes Guerci-Bresler, Lu
Publié dans: Blood Advances, Numéro 2/16, 2018, Page(s) 2079-2089, ISSN 2473-9529
Éditeur: American Society of Hematology
DOI: 10.1182/bloodadvances.2018020495

Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome

Auteurs: H. K. G. Garelius, W. T. Johnston, A. G. Smith, S. Park, L. de Swart, P. Fenaux, A. Symeonidis, G. Sanz, J. Čermák, R. Stauder, L. Malcovati, M. Mittelman, A. A. van de Loosdrecht, C. J. van Marrewijk, D. Bowen, S. Crouch, T. J. M. de Witte, E. Hellström-Lindberg
Publié dans: Journal of Internal Medicine, Numéro 281/3, 2016, Page(s) 284-299, ISSN 0954-6820
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/joim.12579

appreci8: a pipeline for precise variant calling integrating 8 tools

Auteurs: Sarah Sandmann, Mohsen Karimi, Aniek O de Graaf, Christian Rohde, Stefanie Göllner, Julian Varghese, Jan Ernsting, Gunilla Walldin, Bert A van der Reijden, Carsten Müller-Tidow, Luca Malcovati, Eva Hellström-Lindberg, Joop H Jansen, Martin Dugas
Publié dans: Bioinformatics, Numéro 34/24, 2018, Page(s) 4205-4212, ISSN 1367-4803
Éditeur: Oxford University Press
DOI: 10.1093/bioinformatics/bty518

ODM Data Analysis—A tool for the automatic validation, monitoring and generation of generic descriptive statistics of patient data

Auteurs: Tobias Johannes Brix, Philipp Bruland, Saad Sarfraz, Jan Ernsting, Philipp Neuhaus, Michael Storck, Justin Doods, Sonja Ständer, Martin Dugas
Publié dans: PLOS ONE, Numéro 13/6, 2018, Page(s) e0199242, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0199242

Association of anemia with health-related quality of life and survival: a large population-based cohort study

Auteurs: Hanneke J.C.M. Wouters, Melanie M. van der Klauw, Theo de Witte, Reinhard Stauder, Dorine W. Swinkels, Bruce H.R. Wolffenbuttel, Gerwin Huls
Publié dans: Haematologica, Numéro 104/3, 2019, Page(s) 468-476, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.195552

Multidisciplinary care in the hematology clinic: Implementation of geriatric oncology

Auteurs: Valentin Goede, Reinhard Stauder
Publié dans: Journal of Geriatric Oncology, Numéro 10/3, 2019, Page(s) 497-503, ISSN 1879-4068
Éditeur: Elsevier BV
DOI: 10.1016/j.jgo.2018.09.003

Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals

Auteurs: Isabelle A. van Zeventer, Aniek O. de Graaf, Hanneke JCM Wouters, Bert A. Van der Reijden, Melanie van der Klauw, Theo M de Witte, Marianne A. Jonker, Luca Malcovati, Joop H Jansen, Geert Huls
Publié dans: Blood, Numéro 135(14), 2020, Page(s) 1161-1170, ISSN 0006-4971
Éditeur: American Society of Hematology
DOI: 10.1182/blood.2019004362

AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting

Auteurs: Christian Wünsch, Henrik Banck, Carsten Müller-Tidow, Martin Dugas
Publié dans: BMC Medical Genomics, Numéro 13/1, 2020, ISSN 1755-8794
Éditeur: BioMed Central
DOI: 10.1186/s12920-020-0668-3

Myelodysplastic syndromes: moving towards personalized management

Auteurs: Eva Hellström-Lindberg, Magnus Tobiasson, Peter Greenberg
Publié dans: Haematologica, Numéro 105/7, 2020, Page(s) 1765-1779, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.248955

Algorithm using clinical and lab parameters may assist in ruling out and in diagnosing MDS

Auteurs: Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T and Mittelman M
Publié dans: Blood Advances, Numéro (accepted for publication), 2020, ISSN 0887-6924
Éditeur: Nature Publishing Group

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome

Auteurs: Marlijn Hoeks, Tim Bagguley, Corine van Marrewijk, Alex Smith, David Bowen, Dominic Culligan, Seye Kolade, Argiris Symeonidis, Hege Garelius, Michail Spanoudakis, Saskia Langemeijer, Rian Roelofs, Erwin Wiegerinck, Aurelia Tatic, Sally Killick, Panagiotis Panagiotidis, Oana Stanca, Eva Hellström-Lindberg, Jaroslav Cermak, Melanie van der Klauw, Hanneke Wouters, Marian van Kraaij, Nicole Blijleven
Publié dans: Leukemia, Numéro Sep 18. [Epub ahead of print], 2020, Page(s) 2021 Jun;35(6):1745-1750 [jounal version], ISSN 0887-6924
Éditeur: Nature Publishing Group
DOI: 10.1038/s41375-020-01022-2

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

Auteurs: Theo De Witte, Luca Malcovati, Pierre Fenaux, David Bowen, Argiris Symeonidis, Moshe Mittelman, Reinhard Stauder, Guillermo Sanz, Jaroslav Čermák, Saskia Langemeijer, Eva Hellström-Lindberg, Ulrich Germing, Mette Skov Holm, Krzysztof Mądry, Aurelia Tatic, António Medina Almeida, Aleksandar Savic, Inga Mandac Rogulj, Raphael Itzykson, Marlijn Hoeks, Hege Gravdahl Garelius, Dominic Culligan, Io
Publié dans: Haematologica, Numéro 105/11, 2020, Page(s) 2516-2523, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.266817

Core Set of Patient-Reported Outcomes for Myelodysplastic Syndromes - EUMDS Delphi Study in Patients and Hematologists

Auteurs: Igor Stojkov, Annette Conrads-Frank, Ursula Rochau, Karin A. Koinig, Marjan Arvandi, Sibylle Puntscher, Corine van Marrewijk, Pierre Fenaux, Argiris Symeonidis, Fatiha Chermat, Hege Garelius, David Bowen, Moshe Mittelman, Elvira Mora, Theo de Witte, Fabio Efficace, MD, Uwe Siebert, Reinhard Stauder
Publié dans: Blood Advances, Numéro (under peer-review - revision invited), 2020, ISSN 0006-4971
Éditeur: American Society of Hematology

Comparison of Open-access Databases for Clinical Variant Interpretation in Cancer: A Case Study of MDS/AML

Auteurs: HENRIK BANCK, MARTIN DUGAS, CARSTEN MÜLLER-TIDOW, SARAH SANDMANN
Publié dans: Cancer Genomics - Proteomics, Numéro 18/2, 2021, Page(s) 157-166, ISSN 1109-6535
Éditeur: International Institute of Anticancer Research
DOI: 10.21873/cgp.20250

Computational analysis of flow cytometry data in hematological malignancies: future clinical practice?

Auteurs: Carolien Duetz, Costa Bachas, Theresia M. Westers, Arjan A. van de Loosdrecht
Publié dans: Current Opinion in Oncology, Numéro 32/2, 2020, Page(s) 162-169, ISSN 1040-8746
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/cco.0000000000000607

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Auteurs: Marlijn Hoeks, Ge Yu, Saskia Langemeijer, Simon Crouch, Louise de Swart, Pierre Fenaux, Argiris Symeonidis, Jaroslav Čermák, Eva Hellström-Lindberg, Guillermo Sanz, Reinhard Stauder, Mette Skov Holm, Moshe Mittelman, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Antonio Medina Almeida, Ulrich Germing, Aleksandar Savic, Njetočka Gredelj Šimec, Dominic Culligan, Raphael Itzykson, Agnes Guerc
Publié dans: Haematologica, Numéro 105/3, 2020, Page(s) 640-651, ISSN 0390-6078
Éditeur: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212332

Development of a core outcome set for myelodysplastic syndromes – a Delphi study from the EUMDS Registry Group

Auteurs: Ursula Rochau, Igor Stojkov, Annette Conrads‐Frank, Helena H. Borba, Karin A. Koinig, Marjan Arvandi, Corine Marrewijk, Hege Garelius, Ulrich Germing, Argiris Symeonidis, Guillermo F. Sanz, Pierre Fenaux, Theo Witte, Fabio Efficace, Uwe Siebert, Reinhard Stauder
Publié dans: British Journal of Haematology, Numéro 191/3, 2020, Page(s) 405-417, ISSN 0007-1048
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/bjh.16654

Myelodysplastisch syndroom

Auteurs: van de Loostdrecht AA
Publié dans: Nederlands Tijdschrift voor Hematologie [In Dutch], Numéro DHC special April, 2020, ISSN 1572-1590
Éditeur: Ariez B.V.

Mutatiespectrum en dynamiek van klonale hematopoëse bij ouderen met anemie

Auteurs: van Zeventer, I
Publié dans: Nederlands Tijdschrift voor Hematologie [In Dutch], Numéro DHC special April, 2020, ISSN 1572-1590
Éditeur: Ariez B.V.

IJzerchelatie bij laag-risico myelodysplsie

Auteurs: Langemeijer S (& Hoeks M)
Publié dans: Nederlands Tijdschrift voor Hematologie, Numéro DHC special April 2018, 2018, Page(s) 18-19, ISSN 1572-1590
Éditeur: Ariez B.V.

MDS: de juiste zorg op het juiste moment - MDS is een complexe en relatief zeldzame ziekte, maar het aantal patiënten groeit. Het project MDS-RIGHT heeft tot doel de zorg voor MDS-patiënten te verbeteren. Op welke manier?

Auteurs: de Witte, T (Gal M)
Publié dans: HEMATON [In Dutch], Numéro Magazine 16 Winter 2017, 2017, Page(s) 28-31
Éditeur: Stichting Hematon

Immuunfenotype als voorspeller voor pregressie bij MDS

Auteurs: van Spronsen M
Publié dans: Nederlands Tijdschrift voor Hematologie [In Dutch], Numéro DHC special April, 2018, Page(s) 11, ISSN 1572-1590
Éditeur: Ariez B.V.

Anemie en kwaliteit van leven

Auteurs: Wouters HJCM
Publié dans: Nederlands Tijdschrift voor Hematologie [In Dutch], Numéro DHC special April, 2018, Page(s) 12, ISSN 1572-1590
Éditeur: Ariez B.V.

Moleculaire Diagnostiek

Auteurs: Jansen J
Publié dans: Nederlands Tijdschrift voor Hematologie [In Dutch], Numéro DHC special April, 2018, Page(s) 54, ISSN 1572-1590
Éditeur: Ariez B.V.

Patiënten met laagrisico-MDS: met het oog op ijzergerelateerde problematiek

Auteurs: de Swart L
Publié dans: Medidact – Hematlogie [In Dutch], Numéro Augustus vol. 4 / nr. 4, 2019, Page(s) 18
Éditeur: unknown

De nieuwste ontwikkelingen op het gebied van ijzerstapeling bij myelodysplastisch syndroom

Auteurs: Hoeks M, Zwaginga JJ
Publié dans: Hematologie Actueel [In Dutch], Numéro Jaargang 19 | nr. 2 | september 2019 [In Dutch], 2019
Éditeur: Academic Pharmaceutical Productions bv

Red blood cell transfusions in hemato-oncological patients - Don't iron out the consequences

Auteurs: Marlijn Hoeks, MD
Publié dans: Numéro 3 November, 2020, ISBN 978-94-6421-027-9
Éditeur: Ipskamp Printing

The mutational landscape and microenvironment in Myelodysplastic Syndromes with deletion of chromosome 5q

Auteurs: Christian Scharenberg, MD
Publié dans: Numéro 2 March, 2018, ISBN 978-91-7676-985-0
Éditeur: Karolinska Institutet

Registry studies on myelodysplastic syndrome and secondary acute myeloid leukemia

Auteurs: Hege Garelius, MD
Publié dans: Numéro 4 May, 2018, ISBN 978-91-629-0488-3
Éditeur: BrandFactory

Patients with lower-risk myelodysplastic syndromes: in scope of iron related complications

Auteurs: Louise de Swart
Publié dans: Numéro 12 June, 2019, ISBN 978-94-6380-330-4
Éditeur: ProefschriftMaken.nl

Translational regulations in normal and pathological erythropoiesis

Auteurs: Ismael Boussaid
Publié dans: UNIVERSITÉ DE PARIS, 2020
Éditeur: HAL OPEN SCIENCE

The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]

Auteurs: Robin M, de Witte T. Myelodysplastic Syndromes. In: Carreras E, Dufour C, Mohty M, Kröger N, editors.
Publié dans: The EBMT Handbook, 7th ed., Numéro Chapter 73, 2019
Éditeur: Springer

Recherche de données OpenAIRE...

Livrables

Publications

Partager cette page

Télécharger