Providing the right care to the right patient with MyeloDysplastic Syndrome at the right time

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Updated patient handbooks of the national MDS patient groups
Operational project specific MDS-RIGHT website
Yearly electronic updates of the evidence-based therapeutic guidelines

Yearly electronic updates of the evidencebased therapeutic guidelines

Discussion platforms and a common website for stakeholder interaction
Yearly updates of MDS website

Report of two meetings on state-of-the-art in the field of MDS
Report on the endorsement of the new evidence-based guidelines for MDS patients
Final dataset incorporating data generated from WP2, WP3 & WP4
Periodic report on mutational sequencing and epigenetic profiling in various cohorts

Reports on mutational sequencing and epigenetic profiling in various cohorts

Report of ethical, legal, and socio-economical aspects of the elderly low risk MDS population
Completed catalogue of all MDS caregiver cooperative groups, patient support groups and existing documents
Report on the newly defined burden of MDS on HRQoL in MDS and nonMDS cohorts
Report describing the flexible electronic web-based system with evidence-based guidelines for MDS
Yearly MDS Stakeholders Newsletters
Report on the participation in international patient support group meetings.
Report on new COS including patient-reported, disease-specific outcomes
Report of new predictors and prediction functions for impaired HRQoL
Final analyses of models from D1.3 for use in WP5 and WP6
Final report of WP1 and preparation of manuscripts
Validation of a MDS-specific HRQoL questionnaire (QUALMS-1)
A list of HRQoL-adapted treatments for each biologic MDS-subtype
Report on newly generated, high-quality health economic evidence of benefit by personalised MDS care strategies
Periodic report on immunophenotyping in various cohorts
Approved European and International guidelines uploaded at new ELN-linked website
Periodic report on bioinformatic integration of data
Report describing prognostic impact of newly defined individual genetic defects on response to the existing HCI
Report on ms data 100 blood samples with 100 paired BM samples

List of newly identified genetic defects that support development of novel drugs
Report of new specific genetic signatures that support minimal diagnostic criteria recognizing MDS in older individuals
Description of effect estimates for various health-care interventions on HRQoL
Promotion of educational and scientific meetings, pocket cards, posters, flyers, exhibition booth for meetings
A set of measures and prediction functions of HRQoL
Report of early treatment response indicators supporting a targeted use of existing HCI

Scientific, Clinical and Ethics Advisory Board

Appointment of Scientific, Clinical and Ethics Advisory Board

Publicaciones

Moleculaire diagnostiek

Autores: Jansen J
Publicado en: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Hematologie, Edición DHC special April, 2018, ISSN 1572-1590
Editor: Ariez B.V.

Immuunfenotype als voorspeller oor progressie bij MDS

Autores: van Spronsen et al.
Publicado en: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Geneeskunde, Edición DHC special April, 2018, ISSN 1572-1590
Editor: Ariez B.V.

DTUrtle – Differential transcript usage analysis for bulk and single-cell data

Autores: Tekath T, Dugas M
Publicado en: 28th International Conference on Intelligent Systems for Molecular Biology (ISMB) 2020, Edición 31 July 2020, 2020, ISSN 2046-1402
Editor: F1000 Research Ltd

A variant erythroferrone induced by clonal erythropoiesis disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Autores: Bondu S
Publicado en: 2019
Editor: ?

A variant erythroferrone induced by clonal erythropoiesis disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Autores: Bondu S
Publicado en: 2020
Editor: ?

Longitudinal Study on Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Autores: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig KA, Schomaker M, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Cermak J, Sanz GF, Hellstrom Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci Bresler A, Culligan DJ, Kotsianidis I, Sanhes L, Mills J, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Siebert U, Stauder R
Publicado en: American Society of Hematology 2020 (62nd) Annual meeting; published in: Blood, Edición December 2020, 2020
Editor: American Society of Hematology

Diagnose en prognose van MDS [In Dutch]

Autores: vd Loosdrecht AA
Publicado en: Dutch Hematology Congress 2020, published in: Nederlands Tijdshrift voor Hematologie, 2020, ISSN 1572-1590
Editor: Ariez B.V.

Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Autores: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig K, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Stauder R, Siebert U
Publicado en: 42nd Annual North American Meeting of the Society for Medical Decision Making; published in: Med Decis Making, Edición October 2020, 2020
Editor: Society for Medical Decision Making

Impact of Treatment with Iron Chelation Therapy in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Autores: Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Skov-Holm M, Mittelman M, Madry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj-Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van Marrewijk C, Droste J, van Kraaij M, Bowen DT, de Witte TM, Smith A.
Publicado en: Blood, Edición 130, S1, 2017, Página(s) "#425"
Editor: American Society of Hematology

Identifying Predictors for Low Health-Related Quality of Life in Patients with Myelodysplastic Syndromes – Research Protocol

Autores: Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U
Publicado en: Annual Conference of the German Network for Evidence-based Medicine, 2018
Editor: German Medical Science Publishing House

Impact of Treatment with Iron Chelation Therapy in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Autores: Hoeks M, Yu G, Langemeijer S, Crouch S, de Swart L, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Skov-Holm M, Mittelman M, Madry K, Malcovati L, Tatic A, Almeida AM, Germing U, Savic A, Gredelj-Šimec N, Culligan D, Itzykson R, Guerci-Bresler A, Slama B, van Marrewijk C, Droste J, van Kraaij M, Bowen DT, de Witte TM, Smith A.
Publicado en: Dutch Hematology Congress 2018, published in: Nederlands Tijdshrift voor Geneeskunde, 2018
Editor: Ariez B.V.

Impact of anemia on health-related quality of life depends on age and etiology

Autores: Wouters HJCM, Van der Klauw MM, de Witte T, Stauder R, Swinkels DW, Wolffenbuttel BHR, Huls G
Publicado en: Dutch Hematology Congress 2018 (Nederlands Tijdshrift voor Geneeskunde), 2018
Editor: Ariez B.V.

Impact of Red Blood Cell Transfusion Intensity on Progression-Free Survival in Lower-Risk MDS Patients Included in the European Leukemianet MDS Registry

Autores: de Swart L, Crouch S, Hoeks M, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Cermak J, Stauder R, Mittelman M, Sanz G, Hellstrom-Lindberg E, Malcovati L, Holm MS, Germing U, Madry K, Almeida AM, Tatic A, Savic A, Gredelj-Šimec N, Guerci Bresler A, Culligan D, Itzykson R, Beyne-Rauzy O, Park S, van Marrewijk C, Blijlevens NMA Bowen DT, de Witte TM.
Publicado en: Blood, Edición 130, S1, 2017, Página(s) "#1690"
Editor: American Society of Hematology

Identifying Multinational Cost Data: A Methodological Review and Case Study

Autores: Thomas Patton, Chu-Mei Hung, Martin Henriksson, Mirjana Huić, Ana Patrícia Marques, Sibylle Puntscher, Đurđa Vukićević, Matteo Ruggeri, Andrea Manca
Publicado en: EUHEA conference 2018, Maastricht, Edición July 2018, 2018
Editor: European Health Economics Association

Appreci8: a pipeline for precise variant calling integrating 8 tools

Autores: Sandmann S, de Graaf AO, Karimi M, van der Reijden BA, Hellström-Lindberg E, Jansen JH, Dugas M
Publicado en: Haematologica, Edición 102,S2, Jun 26, 2017
Editor: Ferrata Storti Foundation

Deriving Core Outcomes for Myelodysplastic Syndromes – Health Professionals’ Perspective

Systematic Overview of Patient-Reported Outcomes for Myelodysplastic Syndromes

Autores: Stojkov I, Rochau U, Conrads-Frank A, Borba HH, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U.
Publicado en: 17th Biennial European Conference of the Society for Medical Decision Making, 2018
Editor: Sage Publishing

Developing a Core Outcomes for Myelodysplastic Syndromes – The MDS-RIGHT Health Professional Delphi Survey

Autores: Stojkov I, Conrads-Frank A, Rochau U, Koinig K.A., Arvandi M, Symeonidis A, Sanz G, Fenaux P, Bowen D, Mittelmann M, Garelius H, Germing U, van Marrewijk C , Cermak J, Hellström-Lindberg E, Smith A, de Witte T, Efficace F, Siebert U, Stauder R.
Publicado en: 23rd Congress of the European Hematology Association; published in: Haematologica, Edición 103, S1 (June 2018), 2018
Editor: Ferrata Storti Foundation

Prognostic Value of Early Drop in Platelets in Lower-Risk MDS. A Sub-Study from the European Leukemianet Lower-Risk MDS (EUMDS) Registry

Autores: Itzykson R, Smith A, Fenaux P, Symeonidis A, Mittelman M, Stauder R, Sanz G, Cermak J, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Germing U, Madry KM, Holm MS, Tatic A, Almeida AM, Savic A, Gredelj-Šimec N, Bowen D, de Witte T.
Publicado en: Leukemia Research, Edición 55, S1, 2017, Página(s) "#19, S10-11"
Editor: Pergamon Press Ltd.

Impact of Red Blood Cell Transfusion Rate, Adjusted by Therapeutic interventions, on Progression-Free Survival in Lower-Risk MDS Patients within the European LeukemiaNet MDS Registry

Autores: de Swart L, Hoeks M, Crouch S, Smith A, Langemeijer S, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Stauder R, Sanz G, Mittelman M, Holm MS, Malcovati L, Madry K, Germing U, Savic A, Almeida AM, Guerci Bresler A, Itzykson R, Beyne-Rauzy O, Culligan D, van Marrewijk C, Blijlevens NMA Bowen DT, de Witte TM.
Publicado en: Haematologica, Edición 103, S1, 2018
Editor: Ferrata Storti Foundation

Benchmarking Variant Calling Tools for NGS Data

Autores: Sandmann S, de Graaf AO, Karimi M, van der Reijden BA, Hellström-Lindberg E, Jansen JH, Dugas M
Publicado en: F1000Research, Edición 6(ISCB Comm J):1353, 2017
Editor: F1000 Research Ltd

Health-Related Quality of Life Is Substantially Impaired in Lower-Risk MDS When Compared with Reference Populations and Significantly Affects Overall Survival

Autores: Stauder R, Yu G, Koinig K, Fenaux P, Symeonidis A, Sanz G, Cermak J, Mittelman M, Hellstrom-Lindberg E, Langemeijer S, Holm MS, Madry K, Malcovati L, Tatic A, Germing U, Savic A, Efficace F, Smith A, Bowen D, de Witte T.
Publicado en: Leukemia Research, Edición 55, S1, 2017, Página(s) "#22, S12"
Editor: Elsevier

Impact of Red Blood Cell Transfusions on Survival in Lower-Risk MDS Patients Included in the European Leukemianet MDS (EUMDS) Registry

Autores: de Swart L, Crouch S, Smith A, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Malcovati L, Germing U, Langemeijer S, Holm MS, Mittelman M, Mądry K, Almeida A, Savic A, Itzykson R, Bowen D, de Witte T.
Publicado en: Leukemia Research, Edición 55, S1, 2017, Página(s) "#280, S160-161"
Editor: Pergamon Press Ltd.

A Prognostic Classifier Based on Early Platelet Drop in Lower-Risk MDS a Study from the European Leukemianet Lower-Risk MDS (EUMDS) Registry

Autores: Itzykson R, Crouch S, Smith A, Symeonidis A, Hellstrom-Lindberg E, Sanz G, Cermak J, Stauder R, Malcovati L, Germing U, Mittelman M, Langemeijer S, Madry K, Tatic A, Holm MS, Almeida AM, Savic A, Gredelj-Šimec N, Luño Fernandez E, Culligan D, Guerci Bresler A, van Marrewijk C, Bowen DT, de Witte TM, Fenaux P.
Publicado en: Blood, Edición 130, S1, 2017, Página(s) "#158"
Editor: American Society of Hematology

Detecting small structural variants in amplicon-based NGS data - an evaluation of ten algorithms

Autores: Marius Wöste, Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen, and Martin Dugas
Publicado en: ISMB abstrats, 2017
Editor: F1000Research

Developing a Core Outcome Set for Myelodysplastic Syndromes - an International Delphi Survey

Autores: Stojkov I, Rochau U, Conrads-Frank A, Koinig K.A., Arvandi M, Symeonidis A, Sanz G, Fenaux P, Bowen D, Mittelmann M, Garelius H, Germing U, van Marrewijk C , Cermak J, Hellström-Lindberg E, Smith A, de Witte T, Efficace F, Stauder R, Siebert U.
Publicado en: 40th Annual North American Meeting of the Society for Medical Decision Making, Edición october 2018, 2018
Editor: F1000 Research Ltd

Impact van behandeling met ijzerchelatietherapie op patiënten met een laag-risico myelodysplastisch syndroom die deelnemen aan de Europese MDS registratie

Systematic Review of Quality of Life Measurement Instruments and Response Criteria among Patients with Myelodysplastic Syndromes

Autores: Stojkov I, Rochau U, Borba HH, Jevdjevic M, Koinig KA, Arvandi M, Efficace F, Stauder R, Siebert U.
Publicado en: ISPOR 19th Annual European Congress; published in: Value in Health, Edición 19/7 (October 2016), 2016, Página(s) A596, ISSN 1098-3015
Editor: Blackwell Publishing Inc.

Impact of Treatment with Iron Chelators in Lower-Risk MDS Patients Participating in the European Leukemianet MDS (EUMDS) Registry

Autores: Saskia Langemeijer, Louise De Swart, Ge Yu, Alex Smith, Simon Crouch, Tom Johnston, Pierre Fenaux, Argiris Symeonidis, Jaroslav Cermak, Eva Hellstrom-Lindberg, Guillermo Sanz, Reinhard Stauder, Luca Malcovati, Ulrich Germing, Mette Skov Holm, Moshe Mittelman, Krzysztof Madry, Aurelia Tatic, Antonio Almeida, Aleksandar Savic, Sophie Park, Odile Beyne-Rauzy, Raphaël Itzykson, Corine van Marrewijk,
Publicado en: Blood, Edición 128, 2016, Página(s) 3186
Editor: American Society of Hematology

Comparison of 1690 MDS Patients from the European LeukemiaNet Registry and Reference Populations - Evidence for a Significant impairment in QoL in MDS and Definition of Predictors of Diminished QoL

Autores: Reinhard Stauder , Ge Yu , Tim Bagguley , Pierre Fenaux , Argiris Symeonidis , Guillermo Sanz , Jaroslav Cermak , Moshe Mittelman , Eva Hellström-Lindberg , Saskia Langemeijer , Mette Skov Holm , Krzysztof Mądry , Luca Malcovati , Aurelia Tatic , Ulrich Germing , Aleksandar Savic , Corine van Marrewijk , Agnès Guerci-Bresler , Elisa Luño , Jackie Droste , Karin Koinig , Alex Smith , David Bowe
Publicado en: Hematologica, Edición Volume: 101 Pages: 16-17 Supplement: 1 Meeting Abstract: S13, 2016
Editor: Ferrata Storti Foundation

Systematic Overview of Response Criteria among Patients with Myelodysplastic Syndromes

Autores: I Stojkov, U Rochau, HH Borba, M Jevdjevic, K Koinig, M Arvandi, F Efficace, R Stauder, U Siebert
Publicado en: Society for Medical Decision Making, 38th Annual North American Meeting; published in Value in Health, Edición 19/7, 2016, Página(s) A596 (PSY119), ISSN 1098-3015
Editor: Blackwell Publishing Inc.

Elevated Labile Plasma Iron Levels (LPI) and Increased Oxidative Stress Are Associated with Red Blood Cell Transfusions in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Subtitle: from the European Leukemianet MDS Registry

Autores: Marlijn Hoeks, Saskia Langemeijer, Louise De Swart, Tim Bagguley, Corine van Marrewijk, David Bowen, Jaroslav Cermak, Eva Hellstrom-Lindberg, Aurelia Tatic, Argiris Symeonidis, Marian G.J. Van Kraaij, Panagiotis Panagiotidis, Hege Garelius, Dominic J Culligan, Marta Krejci, Jackie Droste, Alexandra Smith, Dorine W. Swinkels and Theo de Witte
Publicado en: Blood, Edición 128, 2016, Página(s) 4327
Editor: The American Society of Hematology

Evaluating and Optimizing Variant Calling: A Comparison of Roche 454, Ion Torrent PGM and Illumina NextSeq Sequencing Data

Autores: Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen and Martin Dugas
Publicado en: F1000Research, 2015
Editor: F1000Research

Confident Variant Calling in NGS Data – A Mission Impossible?

Autores: Sarah Sandmann, Aniek de Graaf, Bert van der Reijden, Joop Jansen and Martin Dugas
Publicado en: F1000Research, 2016
Editor: F1000Research

Elevated Labile Plasma Iron (LPI) Levels in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Are Associated with Decreased Quality of Life and Reduced Survival

Autores: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellström-Lindberg E, Tatic A, Langemeijer S, Culligan DJ, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels DW, and de Witte TM
Publicado en: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Edición 132, S1, 2018, Página(s) 4392
Editor: American Society of Hematology

DTUrtle – an easily accessible Differential Transcript Usage analysis pipeline

Autores: Tekath T, Dugas M
Publicado en: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Edición 14-Aug, 2019, Página(s) 8-1434, ISSN 2046-1402
Editor: F1000 Research Ltd

New prognostic indicators in MDS identified during the first 10 years of the EUropean LeukemiaNet MDS (EUMDS) Registry

Autores: de Witte T, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Langemeijer S, Germing U, Holm MS, Mądry K, Tatic A, Almeida AM, Savic A, Gredelj Šimec N, Itzykson R, Culligan D, Kotsianidis I, Ades L, van de Loosdrecht AA, van Marrewijk C, Yu G, Crouch S, Malcovati L, Smith A, on behalf of the EUMDS Registry Participants
Publicado en: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Editor: Pergamon Press Ltd.

Can We Diagnose MDS without Bone Marrow Examination? a Proposed EUMDS-Based Non-Invasive Diagnostic Model

Autores: Oster HS, Shrkihe BA, Crouch S, Smith A, Yu G, Carmi G, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Tatic A, Almeida AM, Savic A, Gredelj-Šimec N, Guerci Bresler A, van Marrewijk C, Bowen DT, de Witte TMM, Mittelman M
Publicado en: American Society of Hematology 2017 (59th) Annual meeting; published in: Blood, Edición 130, S1, 2017, Página(s) 2975
Editor: American Society of Hematology

Deriving Core Patient-Reported Outcomes in Patients with Myelodysplastic Syndromes - a Delphi Survey from the European-MDS Registry

Autores: Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Borba H, Arvandi M, Fenaux P, Symeonidis A, Bowen DT, Mittelman M, van Marrewijk C, de Witte T, Efficace F, Siebert U and Stauder R
Publicado en: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Edición 132, S1, 2018, Página(s) 2295
Editor: American Society of Hematology

Transfusie-afhankelijkheid is geassocieerd met de aanwezigheid van toxische ijzersoorten en slechtere overleving bij patiënten met een laag-risico myelodysplastisch syndroom

Autores: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Publicado en: Nederlandse Vereniging voor Bloedtransfusie - TRIP Symposium 2019; published in: unknown, 2019, Página(s) "#27"
Editor: unknown

I-CARE for MDS: Development of Guidelines-Based Indicators for Appropriate Care in Adult Patients with Myelodysplastic Syndromes

Autores: Stojkov K, Silzle T, Stussi G, Schwappach D, Bernhard J, Bowen D, Čermák J, Dinmohamed A, Eeltink C, Eggmann S, Fenaux P, Germing U, Haschke M, Hellstrom-Lindberg E, Heger M, van de Loosdrecht AA, Passweg J, Pfeilstöcker M, Platzbecker U, Malcovati L, Almeida AM, Mittelman M, Morgenthaler C, Steensma D, Santini V, Stauder R, Symeonidis A, Schaer S, Maddox C, de Witte T, Bohlius J, Bonadies N
Publicado en: American Society of Hematology 2019 (61th) Annual meeting; published in: Blood, Edición 134, S1, 2019, Página(s) 4752
Editor: American Society of Hematology

Transfusion dependancy is associated with presence of toxic iron species and inferior survival in patients with lower-risk myelodysplastic syndromes

Autores: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Publicado en: International Society of Blood Transfusion (29th) Regional Congress; published in: unknown, 2019
Editor: unknown

Clonal evolution in MDS

Autores: Jansen J
Publicado en: European hematology Association 2017 (22nd) Congress; published in: EHA open access library, 2017
Editor: European Hematology Association

Consensus on a Core Outcome Set for Myelodysplastic syndromes

Autores: Rochau U, Stojkov I, Conrads-Frank A, Borba H, Koining K, Arvandi M, van Marrewijk C, Garelius H, Germing U, Symeonidis A, Sanz G, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R.
Publicado en: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Editor: Pergamon Press Ltd.

Excess Mortality in Low-Risk MDS Can be Explained By MDS and AML Related Causes of Death

Autores: Mądry K, Yu G, Lis K, Fenaux P, Bowen D, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Couch S, de Witte T, Smith A, on behalf of the EUMDS Registry Participants
Publicado en: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Edición 132, S1, 2018, Página(s) 4385
Editor: American Society of Hematology

Transfusion dependancy is associated with presence of toxic iron species and inferior survival in patients with lower-risk myelodysplastic syndromes

Autores: Hoeks M, Bagguley T, Roelofs R, de Swart L, Bowen D, Symeonidis A, van Marrewijk C, Hellstrom-Lindberg E, Tatic A, Langemeijer S, Culligan D, Macheta M, Garelius H, Spanoudakis M, Killick S, Panagiotidis P, Stanca Ciocan O, Mills J, Pottinger B, Ackroyd S, Hall C, Droste J, Smith A, Swinkels D, de Witte T
Publicado en: European hematology Association 2019 (24th) Congress; published in: EHA open access library, Edición 15-Jun, 2019, Página(s) 267421; S838
Editor: European Hematology Association

"Appreci8R: an R package for calling variants the ""appreci8""-way"

Autores: Sandmann S, Dugas M
Publicado en: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Edición 12-Aug, 2019, Página(s) 8-1414, ISSN 2046-1402
Editor: F1000 Research Ltd

Labile Plasma Iron (LPI) Is a Clinical Indicator of Overt Iron Overload in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) from the European Leukemianet MDS Registry

Autores: de Swart L, Reiniers C, Bagguley T, Bowen D, Cermak J, Hellstrom-Lindberg E, Tatic A, Symeonidis A, Huls G, Panagiotidis P, Garelius H, Culligan D, Krejci M, van Marrewijk C, Droste J, Smith A, Swinkels DW, de Witte T
Publicado en: American Society of Hematology 2015 (57th) Annual meeting; published in: Blood, Edición 126/23, 2015, Página(s) 2865
Editor: American Society of Hematology

Longitudinal Changes of Impairments in Health-Related Quality of Life in Lower-Risk MDS Patients: A European Leukemianet Study

Autores: Stauder R, Yu G, Koinig KA, Culligan D, Fenaux P, Cermak J, Symeonidis A, Bernal T, Hellström-Lindberg E, Mittelman M, Langemeijer S, Holm MS, Mills J, Guerci-Bresler A, van Marrewijk C, Garelius H, Efficace F, Smith A, Bowen D, and de Witte TM
Publicado en: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Edición 132, S1, 2018, Página(s) 3097
Editor: American Society of Hematology

How to “appreci8” Variant Calling in NGS Data

Autores: Sandmann S, Dugas M
Publicado en: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Edición 20-Dec, 2019, Página(s) 8-2128, ISSN 2046-1402
Editor: F1000 Research Ltd

A Web Application Could Help in MDS Diagnosis and Obviate the Bone Marrow Examination

Autores: Oster H, Crouch S, Smith A, Yu G, Abu Shrkihe B, Shoham B, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Germing U, Holm MS, Guerci- Bresler A, Culligan D, Laurence S, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M.
Publicado en: MDS-Foundation (15th) International symposium on MDS; published in: Leukemia Research, 2019
Editor: Pergamon Press Ltd.

Prognostic Impact of Transfusions Intensity on Survival and Development of Thrombocytopenia in Newly Diagnosed Lower-Risk MDS Patients Participating in the European Leukemianet EUMDS Registry

Autores: de Swart L, Johnston T, Smith A, Fenaux P, Symeonidis A, Cermak J, Hellstrom-Lindberg E, Sanz G, Stauder R, Malcovati L, Germing U, Huls G, Holm MS, Mittelman M, Madry K, Tatic A, Almeida AM, Savic A, Park S, Beyne-Rauzy O, Itzykson R, van Marrewijk C, Bowen D, de Witte T
Publicado en: American Society of Hematology 2015 (57th) Annual meeting; published in: Blood, Edición 126/23, 2015, Página(s) 1677
Editor: American Society of Hematology

Immunophenotypically Aberrant Stem Cells in Myelodysplastic Syndromes: A Biomarker for Leukemic Progression

Autores: Margot F. Van Spronsen, Theresia M. Westers, Birgit I. Witte, Gert J. Ossenkoppele, Arjan A. Van de Loosdrecht
Publicado en: American Society of Hematology 2017 (59th) Annual meeting; published in: Blood, Edición 130, S1, 2017, Página(s) 4240
Editor: American Society of Hematology

AMLVaran: Improvements in user-friendlyness of a human NGS variant assessment system

Autores: Wünsch C, Dugas M
Publicado en: Intelligent Systems for Molecular Biology (27th) and European Conference on Computational Biology (18th) Annual International Conference; published in: F1000Research, Edición 30-Jul, 2019, Página(s) 8-1232, ISSN 2046-1402
Editor: F1000 Research Ltd

MDS Diagnosis: Many Patients May Not Require Bone Marrow Examination

Autores: Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Cermak J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T and Mittelman M
Publicado en: American Society of Hematology 2018 (60th) Annual meeting; published in: Blood, Edición 132, S1, 2018, Página(s) 4357
Editor: American Society of Hematology

The anemia-independant effect of Myelodysplastic Syndromes on Health-Related Quality of Life

Autores: Wouters H, Conrads-Frank A, Koinig KA, Smith A, Yu G, de Witte T, Wolffenbuttel B, Huls G, Siebert U, Stauder R, van der Klauw M
Publicado en: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Edición 6-dec, 2020, Página(s) 295150; S331
Editor: European Hematology Association

Assessing the Determinants of Health-Related Quality of Life in patients with Myelodysplastic Syndromes

Autores: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig KA, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Siebert U, Stauder R
Publicado en: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Edición 6-dec, 2020, Página(s) 294713; EP796
Editor: European Hematology Association

Impact of Erythropoietin Stimulation Agents and Red Blood Cell Transfusion on Health-related Quality of Life in Lower-risk Myelodysplastic Syndrome

Autores: Garelius H, Smith A, Appleton S, Bowen D, Fenaux P, Symeonidis A, Mittelman M, Stauder R, Čermák J, Sanz G, Langemeijer S, Holm MS, Itzykson R, Culligan D, Heibl S, Mills J, Bernal T, Kotsianidis I, Ades L, Koinig K, van Marrewijk C, Crouch S, de Witte T, Hellström-Lindberg E
Publicado en: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Edición 6-Dec, 2020, Página(s) 294733; EP816
Editor: European Hematology Association

Consensus set of Core Patient-Reported Outcomes for Myelodysplastic Syndromes defined by patients and hematologists - EUMDS Registry group study

Autores: Stojkov I, Conrads-Frank A, Rochau U, Koinig K, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, Symeonidis A, Chermat F, Garelius H, Bowen D, Mittelman M, Mora E, de Witte T, Efficace F, Siebert U, Stauder R
Publicado en: Virtual 25th Congress of European Hematology Association; published in EHA open access library, Edición 6-dec, 2020, Página(s) 294734; EP817
Editor: European Hematology Association

Development of Core Patient-Reported Outcomes in Myelodysplastic Syndromes

Autores: Stojkov I, Conrads-Frank A, Rochau U, Koinig K, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, de Witte T, Efficace F, Siebert U, and Stauder R
Publicado en: Society for Medical Decision Making (18th) Biennial European Conference; published in: Med Decis Making, Edición PS1-20 (June) Postponed to 2022, 2020
Editor: unknown

Determinants of Health-Related Quality of Life in Patients with Myelodysplastic Syndromes

Autores: Stojkov I, Conrads-Frank A, Rochau U, Arvandi M, Koinig K, Schomaker M, Puntscher S, Schmid D, van Marrewijk C, Smith A, de Witte T, Stauder R, and Siebert U
Publicado en: Society for Medical Decision Making (18th) Biennial European Conference, Edición TRA-1-2 (June 2020) Postponed to 2022, 2020
Editor: unknown

Quality of Life in MDS: Relevance for Patients, Physicians, and Stakeholders

Autores: Stauder R.
Publicado en: 2019 Annual Meeting of the German, Austrian and Swiss Societies of Hematology and Medical Oncology, Edición October, 2019
Editor: unknown

Relevance of patient-reported outcomes (PROs) in patients with cancer at advanced age

Autores: Stauder R.
Publicado en: 2019 Annual Meeting of the German, Austrian and Swiss Societies of Hematology and Medical Oncology, Edición October, 2019
Editor: unknown

Computational flow cytometry: a diagnostic tool in MDS

Autores: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, van de Loosdrecht AA
Publicado en: EMSCO 6th annual meeting, Amsterdam, The Netherlands 21-22 sept 2018, published in: unknown, Edición September, 2018
Editor: unknown

Artificial intelligence for flow cytometry data analysis in suspected-MDS enables an accurate, objective and fast diagnosis

Autores: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Publicado en: MDS-Foundation (15th) International symposium on MDS; published in: Unknown, Edición May, 2019
Editor: 1452126

Artificial intelligence improves flow cytometry diagnostics in myelodysplastic syndromes

Autores: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Publicado en: Cancer Research UK - New Directions in Immuno-Oncolog, London UK, Published in : unknown, Edición September, 2019
Editor: unknown

Computational flow cytometry: a novel diagnostic tool in myelodysplastic syndromes

Autores: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, van de Loosdrecht AA
Publicado en: Dutch Hematology Congress 2019, published in: Nederlands Tijdshrift voor Hematologie, Edición October, 2019, ISSN 1572-1590
Editor: Ariez B.V.

Mutation Profiles Identify Distinct Clusters of Lower Risk Myelodysplastic Syndromes with Unique Clinical and Biological Features and Clinical Endpoints

Autores: Malcovati L , Crouch S, de Graaf AO, Sandmann S, Tobiasson M, Kosmider O, van der Reijden BA, Painter D , van de Loosdrecht AA , Symeonidis A, Cermak J, Clappier E, Preudhomme C, Staudern R, Mittelman M, Germing U, Bowen D, Fenaux P, van Marrewijk C, Smith A, Dugas M, Hellstrom Lindberg E, de Witte TM , Fontenay M, Jansen J
Publicado en: American Society of Hematology 2020 (62nd) Annual meeting; published in: Blood, Edición 136/S1 (5 November 2020), 2020, Página(s) 29
Editor: American Society of Hematology

A Web Application Could Help Diagnose or Exclude MDS, Providing a Noninvasive Alternative to Bone Marrow Examination

Autores: Oster H, Crouch S, Smith A, Yu G, Ben-Ezra J, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Mądry K, Guerci- Bresler A, Culligan D, Laurence S, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T, Mittelman M.
Publicado en: American Society of Hematology 2019 (61th) Annual meeting; Submitted, 2019
Editor: -

Analyzing coverage in smMIPs data

Autores: Sandmann S, de Graaf AO, Jansen JH, Dugas M
Publicado en: German Conference on Bioinformatics (2020); published in: F1000Research, Edición 29 September 2020, 2020, ISSN 2046-1402
Editor: F1000 Research Ltd

How to “appreci8” Variant Calling in NGS Data

Autores: Sandmann S, Dugas M
Publicado en: German Conference on Bioinformatics, Edición September 2019, 2019
Editor: ?

Delphi-Survey-Based Development of Core Patient-Reported Outcomes in Myelodysplastic Syndromes

Autores: Stojkov I, Conrads-Frank A, Rochau U, Koinig KA, Arvandi M, Puntscher S, van Marrewijk C, Fenaux P, de Witte T, Efficace F, Siebert U, Stauder R
Publicado en: 42nd Annual North American Meeting of the Society for Medical Decision Making; published in: Med Decis Making, Edición October 2020, 2020
Editor: Society for Medical Decision Making

Mutatiespectrum en dynamiek van klonale hematopoése bij ouderen met anemie [In Dutch]

Autores: van Zeventer et al.
Publicado en: Dutch Hematology Congress 2020, published in: Nederlands Tijdshrift voor Hematologie, 2020, ISSN 1572-1590
Editor: Ariez B.V.

Distinct bone marrow immunophenotypic features define the splicing factor 3B subunit 1 ( SF3B1 )‐mutant myelodysplastic syndromes subtype

Autores: Carolien Duetz, Theresia M. Westers, Florentien E. M. in ’t Hout, Eline M. P. Cremers, Canan Alhan, Bianca Venniker‐Punt, Heleen A. Visser‐Wisselaar, Dana A. Chitu, Aniek O. Graaf, Linda Smit, Joop H. Jansen, Arjan A. Loosdrecht
Publicado en: British Journal of Haematology, Edición 193/4, 2021, Página(s) 798-803, ISSN 0007-1048
Editor: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17414

Impact of red blood cell transfusion dose density on progression-free survival in patients with lower-risk myelodysplastic syndromes

Autores: Louise de Swart, Simon Crouch, Marlijn Hoeks, Alex Smith, Saskia Langemeijer, Pierre Fenaux, Argiris Symeonidis, Jaroslav Cermâk, Eva Hellström-Lindberg, Reinhard Stauder, Guillermo Sanz, Moshe Mittelman, Mette Skov Holm, Luca Malcovati, Krzysztof Mądry, Ulrich Germing, Aurelia Tatic, Aleksandar Savic, Antonio Medina Almeida, Njetocka Gredelj-Simec, Agnes Guerci-Bresler, Odile Beyne-Rauzy, Domi
Publicado en: Haematologica, Edición 105/3, 2020, Página(s) 632-639, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212217

CopyDetective: Detection threshold–aware copy number variant calling in whole-exome sequencing data

Autores: Sarah Sandmann, Marius Wöste, Aniek O de Graaf, Birgit Burkhardt, Joop H Jansen, Martin Dugas
Publicado en: GigaScience, Edición 9/11, 2020, Página(s) giaa118, ISSN 2047-217X
Editor: Oxford University Press and the Beijing Genomics Institute
DOI: 10.1093/gigascience/giaa118

Multicenter Next-Generation Sequencing Studies between Theory and Practice

Autores: Sarah Sandmann, Aniek O. de Graaf, Magnus Tobiasson, Olivier Kosmider, María Abáigar, Emmanuelle Clappier, Anna Gallì, Bert A. van der Reijden, Luca Malcovati, Pierre Fenaux, María Díez-Campelo, Michaela Fontenay, Eva Hellström-Lindberg, Joop H. Jansen, Martin Dugas
Publicado en: The Journal of Molecular Diagnostics, Edición 23/3, 2021, Página(s) 347-357, ISSN 1525-1578
Editor: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2020.12.001

Immunophenotypic aberrant hematopoietic stem cells in myelodysplastic syndromes: a biomarker for leukemic progression

Autores: van Spronsen M, Hanekamp D, Westers T, Jansen J, Lissenberg-Witte B, Cloos J, Schuurhuis G, van de Loosdrecht AA
Publicado en: Blood, Edición (under peer-review), 2021, ISSN 0006-4971
Editor: American Society of Hematology

Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes.

Autores: Duetz C, van Gassen S, Westers TM, van Spronsen MF, Bachas C, Saeys Y, van de Loosdrecht AA
Publicado en: Cytometry A., Edición (under peer-review - conditionally accepted with minor changes), 2021, ISSN 1552-4922
Editor: John Wiley & Sons Ltd.

Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes

Autores: Louise de Swart, Chloé Reiniers, Timothy Bagguley, Corine van Marrewijk, David Bowen, Eva Hellström-Lindberg, Aurelia Tatic, Argiris Symeonidis, Gerwin Huls, Jaroslav Cermak, Arjan A. van de Loosdrecht, Hege Garelius, Dominic Culligan, Mac Macheta, Michail Spanoudakis, Panagiotis Panagiotidis, Marta Krejci, Nicole Blijlevens, Saskia Langemeijer, Jackie Droste, Dorine W. Swinkels, Alex Smith, The
Publicado en: Haematologica, Edición 103/1, 2017, Página(s) 69-79, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2017.171884

GLM-based optimization of NGS data analysis: A case study of Roche 454, Ion Torrent PGM and Illumina NextSeq sequencing data

Autores: Sarah Sandmann, Aniek O. de Graaf, Bert A. van der Reijden, Joop H. Jansen, Martin Dugas
Publicado en: PLOS ONE, Edición 12/2, 2017, Página(s) e0171983, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0171983

BBCAnalyzer: a visual approach to facilitate variant calling

Autores: Sarah Sandmann, Aniek O. de Graaf, Martin Dugas
Publicado en: BMC Bioinformatics, Edición 18/1, 2017, Página(s) 133: 1-6, ISSN 1471-2105
Editor: BioMed Central
DOI: 10.1186/s12859-017-1549-4

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

Autores: Theo de Witte, David Bowen, Marie Robin, Luca Malcovati, Dietger Niederwieser, Ibrahim Yakoub-Agha, Ghulam J. Mufti, Pierre Fenaux, Guillermo Sanz, Rodrigo Martino, Emilio Paolo Alessandrino, Francesco Onida, Argiris Symeonidis, Jakob Passweg, Guido Kobbe, Arnold Ganser, Uwe Platzbecker, Jürgen Finke, Michel van Gelder, Arjan A. van de Loosdrecht, Per Ljungman, Reinhard Stauder, Liisa Volin, H. J
Publicado en: Blood, Edición 129/13, 2017, Página(s) 1753-1762, ISSN 0006-4971
Editor: American Society of Hematology
DOI: 10.1182/blood-2016-06-724500

Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT

Autores: Gerbrig Berger, Leonie I. Kroeze, Theresia N. Koorenhof-Scheele, Aniek O. de Graaf, Kenichi Yoshida, Hiroo Ueno, Yuichi Shiraishi, Satoru Miyano, Eva van den Berg, Hein Schepers, Bert A. van der Reijden, Seishi Ogawa, Edo Vellenga, Joop H. Jansen
Publicado en: Blood, Edición 131/16, 2018, Página(s) 1846-1857, ISSN 0006-4971
Editor: American Society of Hematology
DOI: 10.1182/blood-2017-09-805879

Autores: Reinhard Stauder, Ge Yu, Karin A. Koinig, Tim Bagguley, Pierre Fenaux, Argiris Symeonidis, Guillermo Sanz, Jaroslav Cermak, Moshe Mittelman, Eva Hellström-Lindberg, Saskia Langemeijer, Mette Skov Holm, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Ulrich Germing, Aleksandar Savic, Corine van Marrewijk, Agnès Guerci-Bresler, Elisa Luño, Jackie Droste, Fabio Efficace, Alex Smith, David Bowen,
Publicado en: Leukemia, Edición 32/6, 2018, Página(s) 1380-1392, ISSN 0887-6924
Editor: Nature Publishing Group
DOI: 10.1038/s41375-018-0089-x

Clonal evolution in myelodysplastic syndromes

Autores: Pedro da Silva-Coelho, Leonie I. Kroeze, Kenichi Yoshida, Theresia N. Koorenhof-Scheele, Ruth Knops, Louis T. van de Locht, Aniek O. de Graaf, Marion Massop, Sarah Sandmann, Martin Dugas, Marian J. Stevens-Kroef, Jaroslav Cermak, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Theo de Witte, Nicole M. A. Blijlevens, Petra Muus, Gerwin Huls, Bert A. van der Reijden, Seishi Ogawa, Joo
Publicado en: Nature Communications, Edición 8, 2017, Página(s) 15099, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/ncomms15099

Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data

Autores: Sarah Sandmann, Aniek O. de Graaf, Mohsen Karimi, Bert A. van der Reijden, Eva Hellström-Lindberg, Joop H. Jansen, Martin Dugas
Publicado en: Scientific Reports, Edición 7, 2017, Página(s) 43169, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/srep43169

VIPER: a web application for rapid expert review of variant calls

Autores: Marius Wöste, Martin Dugas
Publicado en: Bioinformatics, Edición 34/11, 2018, Página(s) 1928-1929, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1093/bioinformatics/bty022

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes

Autores: Raphael Itzykson, Simon Crouch, Erica Travaglino, Alex Smith, Argiris Symeonidis, Eva Hellström-Lindberg, Guillermo Sanz, Jaroslav Čermák, Reinhard Stauder, Chiara Elena, Ulrich Germing, Moshe Mittelman, Saskia Langemeijer, Krzysztof Mądry, Aurelia Tatic, Mette Skov Holm, Antonio Medina Almeida, Aleksandar Savic, Njetočka Gredelj Šimec, Elisa Luño, Dominic Culligan, Agnes Guerci-Bresler, Lu
Publicado en: Blood Advances, Edición 2/16, 2018, Página(s) 2079-2089, ISSN 2473-9529
Editor: American Society of Hematology
DOI: 10.1182/bloodadvances.2018020495

Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome

Autores: H. K. G. Garelius, W. T. Johnston, A. G. Smith, S. Park, L. de Swart, P. Fenaux, A. Symeonidis, G. Sanz, J. Čermák, R. Stauder, L. Malcovati, M. Mittelman, A. A. van de Loosdrecht, C. J. van Marrewijk, D. Bowen, S. Crouch, T. J. M. de Witte, E. Hellström-Lindberg
Publicado en: Journal of Internal Medicine, Edición 281/3, 2016, Página(s) 284-299, ISSN 0954-6820
Editor: Blackwell Publishing Inc.
DOI: 10.1111/joim.12579

appreci8: a pipeline for precise variant calling integrating 8 tools

Autores: Sarah Sandmann, Mohsen Karimi, Aniek O de Graaf, Christian Rohde, Stefanie Göllner, Julian Varghese, Jan Ernsting, Gunilla Walldin, Bert A van der Reijden, Carsten Müller-Tidow, Luca Malcovati, Eva Hellström-Lindberg, Joop H Jansen, Martin Dugas
Publicado en: Bioinformatics, Edición 34/24, 2018, Página(s) 4205-4212, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1093/bioinformatics/bty518

ODM Data Analysis—A tool for the automatic validation, monitoring and generation of generic descriptive statistics of patient data

Autores: Tobias Johannes Brix, Philipp Bruland, Saad Sarfraz, Jan Ernsting, Philipp Neuhaus, Michael Storck, Justin Doods, Sonja Ständer, Martin Dugas
Publicado en: PLOS ONE, Edición 13/6, 2018, Página(s) e0199242, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0199242

Association of anemia with health-related quality of life and survival: a large population-based cohort study

Autores: Hanneke J.C.M. Wouters, Melanie M. van der Klauw, Theo de Witte, Reinhard Stauder, Dorine W. Swinkels, Bruce H.R. Wolffenbuttel, Gerwin Huls
Publicado en: Haematologica, Edición 104/3, 2019, Página(s) 468-476, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.195552

Multidisciplinary care in the hematology clinic: Implementation of geriatric oncology

Autores: Valentin Goede, Reinhard Stauder
Publicado en: Journal of Geriatric Oncology, Edición 10/3, 2019, Página(s) 497-503, ISSN 1879-4068
Editor: Elsevier BV
DOI: 10.1016/j.jgo.2018.09.003

Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals

Autores: Isabelle A. van Zeventer, Aniek O. de Graaf, Hanneke JCM Wouters, Bert A. Van der Reijden, Melanie van der Klauw, Theo M de Witte, Marianne A. Jonker, Luca Malcovati, Joop H Jansen, Geert Huls
Publicado en: Blood, Edición 135(14), 2020, Página(s) 1161-1170, ISSN 0006-4971
Editor: American Society of Hematology
DOI: 10.1182/blood.2019004362

AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting

Autores: Christian Wünsch, Henrik Banck, Carsten Müller-Tidow, Martin Dugas
Publicado en: BMC Medical Genomics, Edición 13/1, 2020, ISSN 1755-8794
Editor: BioMed Central
DOI: 10.1186/s12920-020-0668-3

Myelodysplastic syndromes: moving towards personalized management

Autores: Eva Hellström-Lindberg, Magnus Tobiasson, Peter Greenberg
Publicado en: Haematologica, Edición 105/7, 2020, Página(s) 1765-1779, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.248955

Algorithm using clinical and lab parameters may assist in ruling out and in diagnosing MDS

Autores: Oster HS, Crouch S, Smith A, Yu G, Abu Shrkihe B, Baruch S, Kolomansky A, Ben-Ezra J, Naor S, Fenaux P, Symeonidis A, Stauder R, Čermák J, Sanz G, Hellström-Lindberg E, Malcovati L, Langemeijer S, Germing U, Holm MS, Madry K, Guerci-Bresler A, Culligan D, Sanhes L, Mills J, Kotsianidis I, van Marrewijk C, Bowen D, de Witte T and Mittelman M
Publicado en: Blood Advances, Edición (accepted for publication), 2020, ISSN 0887-6924
Editor: Nature Publishing Group

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome

Autores: Marlijn Hoeks, Tim Bagguley, Corine van Marrewijk, Alex Smith, David Bowen, Dominic Culligan, Seye Kolade, Argiris Symeonidis, Hege Garelius, Michail Spanoudakis, Saskia Langemeijer, Rian Roelofs, Erwin Wiegerinck, Aurelia Tatic, Sally Killick, Panagiotis Panagiotidis, Oana Stanca, Eva Hellström-Lindberg, Jaroslav Cermak, Melanie van der Klauw, Hanneke Wouters, Marian van Kraaij, Nicole Blijleven
Publicado en: Leukemia, Edición Sep 18. [Epub ahead of print], 2020, Página(s) 2021 Jun;35(6):1745-1750 [jounal version], ISSN 0887-6924
Editor: Nature Publishing Group
DOI: 10.1038/s41375-020-01022-2

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

Autores: Theo De Witte, Luca Malcovati, Pierre Fenaux, David Bowen, Argiris Symeonidis, Moshe Mittelman, Reinhard Stauder, Guillermo Sanz, Jaroslav Čermák, Saskia Langemeijer, Eva Hellström-Lindberg, Ulrich Germing, Mette Skov Holm, Krzysztof Mądry, Aurelia Tatic, António Medina Almeida, Aleksandar Savic, Inga Mandac Rogulj, Raphael Itzykson, Marlijn Hoeks, Hege Gravdahl Garelius, Dominic Culligan, Io
Publicado en: Haematologica, Edición 105/11, 2020, Página(s) 2516-2523, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.266817

Core Set of Patient-Reported Outcomes for Myelodysplastic Syndromes - EUMDS Delphi Study in Patients and Hematologists

Autores: Igor Stojkov, Annette Conrads-Frank, Ursula Rochau, Karin A. Koinig, Marjan Arvandi, Sibylle Puntscher, Corine van Marrewijk, Pierre Fenaux, Argiris Symeonidis, Fatiha Chermat, Hege Garelius, David Bowen, Moshe Mittelman, Elvira Mora, Theo de Witte, Fabio Efficace, MD, Uwe Siebert, Reinhard Stauder
Publicado en: Blood Advances, Edición (under peer-review - revision invited), 2020, ISSN 0006-4971
Editor: American Society of Hematology

Comparison of Open-access Databases for Clinical Variant Interpretation in Cancer: A Case Study of MDS/AML

Autores: HENRIK BANCK, MARTIN DUGAS, CARSTEN MÜLLER-TIDOW, SARAH SANDMANN
Publicado en: Cancer Genomics - Proteomics, Edición 18/2, 2021, Página(s) 157-166, ISSN 1109-6535
Editor: International Institute of Anticancer Research
DOI: 10.21873/cgp.20250

Computational analysis of flow cytometry data in hematological malignancies: future clinical practice?

Autores: Carolien Duetz, Costa Bachas, Theresia M. Westers, Arjan A. van de Loosdrecht
Publicado en: Current Opinion in Oncology, Edición 32/2, 2020, Página(s) 162-169, ISSN 1040-8746
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/cco.0000000000000607

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

Autores: Marlijn Hoeks, Ge Yu, Saskia Langemeijer, Simon Crouch, Louise de Swart, Pierre Fenaux, Argiris Symeonidis, Jaroslav Čermák, Eva Hellström-Lindberg, Guillermo Sanz, Reinhard Stauder, Mette Skov Holm, Moshe Mittelman, Krzysztof Mądry, Luca Malcovati, Aurelia Tatic, Antonio Medina Almeida, Ulrich Germing, Aleksandar Savic, Njetočka Gredelj Šimec, Dominic Culligan, Raphael Itzykson, Agnes Guerc
Publicado en: Haematologica, Edición 105/3, 2020, Página(s) 640-651, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.212332

Development of a core outcome set for myelodysplastic syndromes – a Delphi study from the EUMDS Registry Group

Autores: Ursula Rochau, Igor Stojkov, Annette Conrads‐Frank, Helena H. Borba, Karin A. Koinig, Marjan Arvandi, Corine Marrewijk, Hege Garelius, Ulrich Germing, Argiris Symeonidis, Guillermo F. Sanz, Pierre Fenaux, Theo Witte, Fabio Efficace, Uwe Siebert, Reinhard Stauder
Publicado en: British Journal of Haematology, Edición 191/3, 2020, Página(s) 405-417, ISSN 0007-1048
Editor: Blackwell Publishing Inc.
DOI: 10.1111/bjh.16654

Myelodysplastisch syndroom

Autores: van de Loostdrecht AA
Publicado en: Nederlands Tijdschrift voor Hematologie [In Dutch], Edición DHC special April, 2020, ISSN 1572-1590
Editor: Ariez B.V.

Mutatiespectrum en dynamiek van klonale hematopoëse bij ouderen met anemie

Autores: van Zeventer, I
Publicado en: Nederlands Tijdschrift voor Hematologie [In Dutch], Edición DHC special April, 2020, ISSN 1572-1590
Editor: Ariez B.V.

IJzerchelatie bij laag-risico myelodysplsie

Autores: Langemeijer S (& Hoeks M)
Publicado en: Nederlands Tijdschrift voor Hematologie, Edición DHC special April 2018, 2018, Página(s) 18-19, ISSN 1572-1590
Editor: Ariez B.V.

MDS: de juiste zorg op het juiste moment - MDS is een complexe en relatief zeldzame ziekte, maar het aantal patiënten groeit. Het project MDS-RIGHT heeft tot doel de zorg voor MDS-patiënten te verbeteren. Op welke manier?

Autores: de Witte, T (Gal M)
Publicado en: HEMATON [In Dutch], Edición Magazine 16 Winter 2017, 2017, Página(s) 28-31
Editor: Stichting Hematon

Immuunfenotype als voorspeller voor pregressie bij MDS

Autores: van Spronsen M
Publicado en: Nederlands Tijdschrift voor Hematologie [In Dutch], Edición DHC special April, 2018, Página(s) 11, ISSN 1572-1590
Editor: Ariez B.V.

Anemie en kwaliteit van leven

Autores: Wouters HJCM
Publicado en: Nederlands Tijdschrift voor Hematologie [In Dutch], Edición DHC special April, 2018, Página(s) 12, ISSN 1572-1590
Editor: Ariez B.V.

Moleculaire Diagnostiek

Autores: Jansen J
Publicado en: Nederlands Tijdschrift voor Hematologie [In Dutch], Edición DHC special April, 2018, Página(s) 54, ISSN 1572-1590
Editor: Ariez B.V.

Patiënten met laagrisico-MDS: met het oog op ijzergerelateerde problematiek

Autores: de Swart L
Publicado en: Medidact – Hematlogie [In Dutch], Edición Augustus vol. 4 / nr. 4, 2019, Página(s) 18
Editor: unknown

De nieuwste ontwikkelingen op het gebied van ijzerstapeling bij myelodysplastisch syndroom

Autores: Hoeks M, Zwaginga JJ
Publicado en: Hematologie Actueel [In Dutch], Edición Jaargang 19 | nr. 2 | september 2019 [In Dutch], 2019
Editor: Academic Pharmaceutical Productions bv

Red blood cell transfusions in hemato-oncological patients - Don't iron out the consequences

Autores: Marlijn Hoeks, MD
Publicado en: Edición 3 November, 2020, ISBN 978-94-6421-027-9
Editor: Ipskamp Printing

The mutational landscape and microenvironment in Myelodysplastic Syndromes with deletion of chromosome 5q

Autores: Christian Scharenberg, MD
Publicado en: Edición 2 March, 2018, ISBN 978-91-7676-985-0
Editor: Karolinska Institutet

Registry studies on myelodysplastic syndrome and secondary acute myeloid leukemia

Autores: Hege Garelius, MD
Publicado en: Edición 4 May, 2018, ISBN 978-91-629-0488-3
Editor: BrandFactory

Patients with lower-risk myelodysplastic syndromes: in scope of iron related complications

Autores: Louise de Swart
Publicado en: Edición 12 June, 2019, ISBN 978-94-6380-330-4
Editor: ProefschriftMaken.nl

Translational regulations in normal and pathological erythropoiesis

Autores: Ismael Boussaid
Publicado en: UNIVERSITÉ DE PARIS, 2020
Editor: HAL OPEN SCIENCE

The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]

Autores: Robin M, de Witte T. Myelodysplastic Syndromes. In: Carreras E, Dufour C, Mohty M, Kröger N, editors.
Publicado en: The EBMT Handbook, 7th ed., Edición Chapter 73, 2019
Editor: Springer

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