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Personalized Nanomedicines for Leukemia Patients

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Publications

Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer

Author(s): Nidhi Jyotsana, Michael Heuser
Published in: Expert Opinion on Therapeutic Targets, Issue 22/2, 2017, Page(s) 107-121, ISSN 1472-8222
DOI: 10.1080/14728222.2018.1417390

Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation

Author(s): Michael Heuser, Razif Gabdoulline, Patrick Löffeld, Vera Dobbernack, Henriette Kreimeyer, Mira Pankratz, Madita Flintrop, Alessandro Liebich, Sabrina Klesse, Victoria Panagiota, Michael Stadler, Martin Wichmann, Rabia Shahswar, Uwe Platzbecker, Christian Thiede, Thomas Schroeder, Guido Kobbe, Robert Geffers, Brigitte Schlegelberger, Gudrun Göhring, Hans-Heinrich Kreipe, Ulrich Germing, Arnold Ga
Published in: Annals of Hematology, Issue 96/8, 2017, Page(s) 1361-1372, ISSN 0939-5555
DOI: 10.1007/s00277-017-3027-5

Therapy-related myeloid neoplasms: does knowing the origin help to guide treatment?

Author(s): M. Heuser
Published in: Hematology, Issue 2016/1, 2016, Page(s) 24-32, ISSN 1520-4391
DOI: 10.1182/asheducation-2016.1.24

Epigenetics in myelodysplastic syndromes

Author(s): Michael Heuser, Haiyang Yun, Felicitas Thol
Published in: Seminars in Cancer Biology, 2017, ISSN 1044-579X
DOI: 10.1016/j.semcancer.2017.07.009

Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate

Author(s): A Chaturvedi, M M Araujo Cruz, N Jyotsana, A Sharma, R Goparaju, A Schwarzer, K Görlich, R Schottmann, E A Struys, E E Jansen, C Rohde, C Müller-Tidow, R Geffers, G Göhring, A Ganser, F Thol, M Heuser
Published in: Leukemia, Issue 30/8, 2016, Page(s) 1708-1715, ISSN 0887-6924
DOI: 10.1038/leu.2016.71

Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation

Author(s): Nicolaus Kröger, Victoria Panagiota, Anita Badbaran, Tatjana Zabelina, Ioanna Triviai, Michelle Maria Araujo Cruz, Rabia Shahswar, Francis Ayuk, Marten Gehlhaar, Christine Wolschke, Robin Bollin, Carolin Walter, Martin Dugas, Lutz Wiehlmann, Ulrich Lehmann, Christian Koenecke, Anuhar Chaturvedi, Haefaa Alchalby, Michael Stadler, Matthias Eder, Max Christopeit, Gudrun Göhring, Michael Koenigsmann
Published in: Biology of Blood and Marrow Transplantation, Issue 23/7, 2017, Page(s) 1095-1101, ISSN 1083-8791
DOI: 10.1016/j.bbmt.2017.03.034

Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo

Author(s): A Chaturvedi, L Herbst, S Pusch, L Klett, R Goparaju, D Stichel, S Kaulfuss, O Panknin, K Zimmermann, L Toschi, R Neuhaus, A Haegebarth, H Rehwinkel, H Hess-Stumpp, M Bauser, T Bochtler, E A Struys, A Sharma, A Bakkali, R Geffers, M M Araujo-Cruz, F Thol, R Gabdoulline, A Ganser, A D Ho, A von Deimling, K Rippe, M Heuser, A Krämer
Published in: Leukemia, Issue 31/10, 2017, Page(s) 2020-2028, ISSN 0887-6924
DOI: 10.1038/leu.2017.46

Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis

Author(s): F Thol, S Klesse, L Köhler, R Gabdoulline, A Kloos, A Liebich, M Wichmann, A Chaturvedi, J Fabisch, V I Gaidzik, P Paschka, L Bullinger, G Bug, H Serve, G Göhring, B Schlegelberger, M Lübbert, H Kirchner, M Wattad, D Kraemer, B Hertenstein, G Heil, W Fiedler, J Krauter, R F Schlenk, K Döhner, H Döhner, A Ganser, M Heuser
Published in: Leukemia, Issue 31/6, 2017, Page(s) 1286-1295, ISSN 0887-6924
DOI: 10.1038/leu.2016.345

RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo

Author(s): N Jyotsana, A Sharma, A Chaturvedi, M Scherr, F Kuchenbauer, L Sajti, A Barchanski, R Lindner, F Noyan, K-W Sühs, D Grote-Koska, K Brand, H-P Vornlocher, M Stanulla, B Bornhauser, J-P Bourquin, M Eder, F Thol, A Ganser, R K Humphries, E Ramsay, P Cullis, M Heuser
Published in: Leukemia, Issue 32/1, 2017, Page(s) 224-226, ISSN 0887-6924
DOI: 10.1038/leu.2017.269