Pubblicazioni Peer reviewed articles (19) Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML Autori: Felicitas Thol, Razif Gabdoulline, Alessandro Liebich, Piroska Klement, Johannes Schiller, Christian Kandziora, Lothar Hambach, Michael Stadler, Christian Koenecke, Madita Flintrop, Mira Pankratz, Martin Wichmann, Blerina Neziri, Konstantin Büttner, Bennet Heida, Sabrina Klesse, Anuhar Chaturvedi, Arnold Kloos, Gudrun Göhring, Brigitte Schlegelberger, Verena I. Gaidzik, Lars Bullinger, Walter Fi Pubblicato in: Blood, Issue 132/16, 2018, Page(s) 1703-1713, ISSN 0006-4971 Editore: American Society of Hematology DOI: 10.1182/blood-2018-02-829911 Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia Autori: Arnold Kloos, Konstantinos Mintzas, Lina Winckler, Razif Gabdoulline, Yasmine Alwie, Nidhi Jyotsana, Nadine Kattre, Renate Schottmann, Michaela Scherr, Charu Gupta, Felix F. Adams, Adrian Schwarzer, Dirk Heckl, Axel Schambach, Suzan Imren, R. Keith Humphries, Arnold Ganser, Felicitas Thol, Michael Heuser Pubblicato in: Leukemia, 2020, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/s41375-020-0929-3 Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo Autori: Nidhi Jyotsana, Amit Sharma, Anuhar Chaturvedi, Ramachandramouli Budida, Michaela Scherr, Florian Kuchenbauer, Robert Lindner, Fatih Noyan, Kurt-Wolfram Sühs, Martin Stangel, Denis Grote-Koska, Korbinian Brand, Hans-Peter Vornlocher, Matthias Eder, Felicitas Thol, Arnold Ganser, R. Keith Humphries, Euan Ramsay, Pieter Cullis, Michael Heuser Pubblicato in: Annals of Hematology, Issue 98/8, 2019, Page(s) 1905-1918, ISSN 0939-5555 Editore: Springer Verlag DOI: 10.1007/s00277-019-03713-y Synergistic activity of IDH1 inhibitor BAY1436032 with azacitidine in IDH1 mutant acute myeloid leukemia Autori: Anuhar Chaturvedi, Charu Gupta, Razif Gabdoulline, Nora M. Borchert, Ramya Goparaju, Stefan Kaulfuss, Kerstin Görlich, Renate Schottmann, Basem Othman, Julia Welzenbach, Olaf Panknin, Markus Wagner, Robert Geffers, Arnold Ganser, Felicitas Thol, Michael Jeffers, Andrea Haegebarth, Michael Heuser Pubblicato in: Haematologica, 2020, Page(s) haematol.2019.236992, ISSN 0390-6078 Editore: Ferrata Storti Foundation DOI: 10.3324/haematol.2019.236992 Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia Autori: Sagarajit Mohanty, Nidhi Jyotsana, Amit Sharma, Arnold Kloos, Razif Gabdoulline, Basem Othman, Courteney K. Lai, Renate Schottmann, Madhvi Mandhania, Johannes Schmoellerl, Florian Grebien, Euan Ramsay, Anitha Thomas, Hans-Peter Vornlocher, Arnold Ganser, Felicitas Thol, Michael Heuser Pubblicato in: Cancers, Issue 12/10, 2020, Page(s) 2766, ISSN 2072-6694 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers12102766 Combination treatment of an IDH1 inhibitor with chemotherapy in IDH1 mutant acute myeloid leukemia Autori: Charu Gupta, Stefan Kaulfuss, Kerstin Görlich, Basem Othman, Anuhar Chaturvedi, Michael Heuser Pubblicato in: Annals of Hematology, Issue 99/6, 2020, Page(s) 1415-1417, ISSN 0939-5555 Editore: Springer Verlag DOI: 10.1007/s00277-020-04001-w Risk of tumor lysis syndrome in patients with acute myeloid leukemia treated with venetoclax-containing regimens without dose ramp-up Autori: Rabia Shahswar, Gernot Beutel, Razif Gabdoulline, Christian Koenecke, Dominik Markel, Matthias Eder, Michael Stadler, Gudrun Gohring, Brigitte Schlegelberger, Arne Trummer, Juergen Krauter, Felicitas Thol, Michael Heuser Pubblicato in: Annals of Hematology, 2020, ISSN 0939-5555 Editore: Springer Verlag DOI: 10.1007/s00277-020-04181-5 Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer Autori: Nidhi Jyotsana, Michael Heuser Pubblicato in: Expert Opinion on Therapeutic Targets, Issue 22/2, 2017, Page(s) 107-121, ISSN 1472-8222 Editore: Ashley Publications Ltd. DOI: 10.1080/14728222.2018.1417390 Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation Autori: Michael Heuser, Razif Gabdoulline, Patrick Löffeld, Vera Dobbernack, Henriette Kreimeyer, Mira Pankratz, Madita Flintrop, Alessandro Liebich, Sabrina Klesse, Victoria Panagiota, Michael Stadler, Martin Wichmann, Rabia Shahswar, Uwe Platzbecker, Christian Thiede, Thomas Schroeder, Guido Kobbe, Robert Geffers, Brigitte Schlegelberger, Gudrun Göhring, Hans-Heinrich Kreipe, Ulrich Germing, Arnold Ga Pubblicato in: Annals of Hematology, Issue 96/8, 2017, Page(s) 1361-1372, ISSN 0939-5555 Editore: Springer Verlag DOI: 10.1007/s00277-017-3027-5 Therapy-related myeloid neoplasms: does knowing the origin help to guide treatment? Autori: M. Heuser Pubblicato in: Hematology, Issue 2016/1, 2016, Page(s) 24-32, ISSN 1520-4391 Editore: American Society of Hematology DOI: 10.1182/asheducation-2016.1.24 Epigenetics in myelodysplastic syndromes Autori: Michael Heuser, Haiyang Yun, Felicitas Thol Pubblicato in: Seminars in Cancer Biology, 2017, ISSN 1044-579X Editore: Academic Press DOI: 10.1016/j.semcancer.2017.07.009 Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate Autori: A Chaturvedi, M M Araujo Cruz, N Jyotsana, A Sharma, R Goparaju, A Schwarzer, K Görlich, R Schottmann, E A Struys, E E Jansen, C Rohde, C Müller-Tidow, R Geffers, G Göhring, A Ganser, F Thol, M Heuser Pubblicato in: Leukemia, Issue 30/8, 2016, Page(s) 1708-1715, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/leu.2016.71 Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation Autori: Nicolaus Kröger, Victoria Panagiota, Anita Badbaran, Tatjana Zabelina, Ioanna Triviai, Michelle Maria Araujo Cruz, Rabia Shahswar, Francis Ayuk, Marten Gehlhaar, Christine Wolschke, Robin Bollin, Carolin Walter, Martin Dugas, Lutz Wiehlmann, Ulrich Lehmann, Christian Koenecke, Anuhar Chaturvedi, Haefaa Alchalby, Michael Stadler, Matthias Eder, Max Christopeit, Gudrun Göhring, Michael Koenigsmann Pubblicato in: Biology of Blood and Marrow Transplantation, Issue 23/7, 2017, Page(s) 1095-1101, ISSN 1083-8791 Editore: Elsevier BV DOI: 10.1016/j.bbmt.2017.03.034 Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo Autori: A Chaturvedi, L Herbst, S Pusch, L Klett, R Goparaju, D Stichel, S Kaulfuss, O Panknin, K Zimmermann, L Toschi, R Neuhaus, A Haegebarth, H Rehwinkel, H Hess-Stumpp, M Bauser, T Bochtler, E A Struys, A Sharma, A Bakkali, R Geffers, M M Araujo-Cruz, F Thol, R Gabdoulline, A Ganser, A D Ho, A von Deimling, K Rippe, M Heuser, A Krämer Pubblicato in: Leukemia, Issue 31/10, 2017, Page(s) 2020-2028, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/leu.2017.46 Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis Autori: F Thol, S Klesse, L Köhler, R Gabdoulline, A Kloos, A Liebich, M Wichmann, A Chaturvedi, J Fabisch, V I Gaidzik, P Paschka, L Bullinger, G Bug, H Serve, G Göhring, B Schlegelberger, M Lübbert, H Kirchner, M Wattad, D Kraemer, B Hertenstein, G Heil, W Fiedler, J Krauter, R F Schlenk, K Döhner, H Döhner, A Ganser, M Heuser Pubblicato in: Leukemia, Issue 31/6, 2017, Page(s) 1286-1295, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/leu.2016.345 RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo Autori: N Jyotsana, A Sharma, A Chaturvedi, M Scherr, F Kuchenbauer, L Sajti, A Barchanski, R Lindner, F Noyan, K-W Sühs, D Grote-Koska, K Brand, H-P Vornlocher, M Stanulla, B Bornhauser, J-P Bourquin, M Eder, F Thol, A Ganser, R K Humphries, E Ramsay, P Cullis, M Heuser Pubblicato in: Leukemia, Issue 32/1, 2017, Page(s) 224-226, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/leu.2017.269 Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia Autori: Amit Sharma, Nidhi Jyotsana, Razif Gabdoulline, Dirk Heckl, Florian Kuchenbauer, Robert K. Slany, Arnold Ganser, Michael Heuser Pubblicato in: Haematologica, Issue 105/5, 2020, Page(s) 1294-1305, ISSN 0390-6078 Editore: Ferrata Storti Foundation DOI: 10.3324/haematol.2018.211201 In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site Autori: Anuhar Chaturvedi, Ramya Goparaju, Charu Gupta, Julia Weder, Thomas Klünemann, Michelle Maria Araujo Cruz, Arnold Kloos, Kerstin Goerlich, Renate Schottmann, Basem Othman, Eduard A. Struys, Heike Bähre, Denis Grote-Koska, Korbinian Brand, Arnold Ganser, Matthias Preller, Michael Heuser Pubblicato in: Leukemia, Issue 34/2, 2020, Page(s) 416-426, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/s41375-019-0582-x FLA‐IDA salvage chemotherapy combined with a seven‐day course of venetoclax (FLAVIDA) in patients with relapsed/refractory acute leukaemia Autori: Rabia Shahswar, Gernot Beutel, Piroska Klement, Alina Rehberg, Razif Gabdoulline, Christian Koenecke, Dominik Markel, Hendrik Eggers, Matthias Eder, Michael Stadler, Lothar Hambach, Steve Ehrlich, Gudrun Göhring, Brigitte Schlegelberger, Elke Dammann, Marlene Reuter, Martin Wichmann, Blerina Neziri, Arnold Ganser, Felicitas Thol, Michael Heuser Pubblicato in: British Journal of Haematology, Issue 188/3, 2019, ISSN 0007-1048 Editore: Blackwell Publishing Inc. DOI: 10.1111/bjh.16268 È in corso la ricerca di dati su OpenAIRE... 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