Unravelling cross-presentation pathways using a chemical biology approach

Publicaciones

Negatively Charged Lipid Membranes Catalyze Supramolecular Hydrogel Formation

Autores: Frank Versluis, Daphne M. van Elsland, Serhii Mytnyk, Dayinta L. Perrier, Fanny Trausel, Jos M. Poolman, Chandan Maity, Vincent A. A. le Sage, Sander I. van Kasteren, Jan H. van Esch, Rienk Eelkema
Publicado en: Journal of the American Chemical Society, Edición 138/28, 2016, Página(s) 8670-8673, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.6b03853

The Optimization of Bioorthogonal Epitope Ligation within MHC-I Complexes

Autores: Joanna B. Pawlak, Brett J. Hos, Michel J. van de Graaff, Otty A. Megantari, Nico Meeuwenoord, Herman S. Overkleeft, Dmitri V. Filippov, Ferry Ossendorp, Sander I. van Kasteren
Publicado en: ACS Chemical Biology, Edición 11/11, 2016, Página(s) 3172-3178, ISSN 1554-8929
Editor: American Chemical Society
DOI: 10.1021/acschembio.6b00498

Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein

Autores: S. Anwar Jagessar, Inge R. Holtman, Sam Hofman, Elena Morandi, Nicole Heijmans, Jon D. Laman, Bruno Gran, Bart W. Faber, Sander I. van Kasteren, Bart J. L. Eggen, Bert A. ‘t Hart
Publicado en: The Journal of Immunology, Edición 197/4, 2016, Página(s) 1074-1088, ISSN 0022-1767
Editor: American Association of Immunologists
DOI: 10.4049/jimmunol.1600124

Detection of bioorthogonal groups by correlative light and electron microscopy allows imaging of degraded bacteria in phagocytes

Autores: Daphne M. van Elsland, Erik Bos, Wouter de Boer, Herman S. Overkleeft, Abraham J. Koster, Sander I. van Kasteren
Publicado en: Chem. Sci., Edición 7/1, 2016, Página(s) 752-758, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/C5SC02905H

Bioorthogonal Deprotection on the Dendritic Cell Surface for Chemical Control of Antigen Cross-Presentation

Autores: Joanna B. Pawlak, Geoffroy P. P. Gential, Tracy J. Ruckwardt, Jessica S. Bremmers, Nico J. Meeuwenoord, Ferry A. Ossendorp, Herman S. Overkleeft, Dmitri V. Filippov, Sander I. van Kasteren
Publicado en: Angewandte Chemie International Edition, Edición 54/19, 2015, Página(s) 5628-5631, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201500301

Quantification of Bioorthogonal Stability in Immune Phagocytes Using Flow Cytometry Reveals Rapid Degradation of Strained Alkynes

Autores: Thomas Bakkum, Tyrza van Leeuwen, Alexi J. C. Sarris, Daphne M. van Elsland, Dimitrios Poulcharidis, Herman S. Overkleeft, Sander I. van Kasteren
Publicado en: ACS Chemical Biology, Edición 13/5, 2018, Página(s) 1173-1179, ISSN 1554-8929
Editor: American Chemical Society
DOI: 10.1021/acschembio.8b00355

Imaging Bioorthogonal Groups in Their Ultrastructural Context with Electron Microscopy

Autores: Daphne M. van Elsland, Sander I. van Kasteren
Publicado en: Angewandte Chemie International Edition, Edición 55/33, 2016, Página(s) 9472-9473, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201604672

A flow cytometry assay to quantify intercellular exchange of membrane components

Autores: Dimitrios Poulcharidis, Kimberley Belfor, Alexander Kros, Sander I. van Kasteren
Publicado en: Chemical Science, Edición 8/8, 2017, Página(s) 5585-5590, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/c7sc00260b

Chemical Tools for Studying TLR Signaling Dynamics

Autores: Timo Oosenbrug, Michel J. van de Graaff, Maaike E. Ressing, Sander I. van Kasteren
Publicado en: Cell Chemical Biology, Edición 24/7, 2017, Página(s) 801-812, ISSN 2451-9456
Editor: Elsevier
DOI: 10.1016/j.chembiol.2017.05.022

Going Native: Synthesis of Glycoproteins and Glycopeptides via Native Linkages To Study Glycan-Specific Roles in the Immune System

Autores: Mikkel H. S. Marqvorsen, Can Araman, Sander I. van Kasteren
Publicado en: Bioconjugate Chemistry, Edición 30/11, 2019, Página(s) 2715-2726, ISSN 1043-1802
Editor: American Chemical Society
DOI: 10.1021/acs.bioconjchem.9b00588

Amyloid-like Behavior of Site-Specifically Citrullinated Myelin Oligodendrocyte Protein (MOG) Peptide Fragments inside EBV-Infected B-Cells Influences Their Cytotoxicity and Autoimmunogenicity

Autores: Can Araman, Miriam E. van Gent, Nico J. Meeuwenoord, Nicole Heijmans, Mikkel H. S. Marqvorsen, Ward Doelman, Bart W. Faber, Bert A. ’t Hart, Sander I. Van Kasteren
Publicado en: Biochemistry, Edición 58/6, 2018, Página(s) 763-775, ISSN 0006-2960
Editor: American Chemical Society
DOI: 10.1021/acs.biochem.8b00852

Ultrastructural Imaging of Salmonella -Host Interactions Using Super-resolution Correlative Light-Electron Microscopy of Bioorthogonal Pathogens

Autores: Daphne M. van Elsland, Sílvia Pujals, Thomas Bakkum, Erik Bos, Nikolaos Oikonomeas-Koppasis, Ilana Berlin, Jacques Neefjes, Annemarie H. Meijer, Abraham J. Koster, Lorenzo Albertazzi, Sander I. van Kasteren
Publicado en: ChemBioChem, Edición 19/16, 2018, Página(s) 1766-1770, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201800230

Localization of active endogenous and exogenous β‐glucocerebrosidase by correlative light‐electron microscopy in human fibroblasts

Autores: Eline van Meel, Erik Bos, Martijn J. C. van der Lienden, Herman S. Overkleeft, Sander I. van Kasteren, Abraham J. Koster, Johannes M. F. G. Aerts
Publicado en: Traffic, Edición 20/5, 2019, Página(s) 346-356, ISSN 1398-9219
Editor: Blackwell Publishing Inc.
DOI: 10.1111/tra.12641

Immunoproteasome Inhibitor–Doxorubicin Conjugates Target Multiple Myeloma Cells and Release Doxorubicin upon Low-Dose Photon Irradiation

Autores: Elmer Maurits, Michel J. van de Graaff, Santina Maiorana, Dennis P. A. Wander, Patrick M. Dekker, Sabina Y. van der Zanden, Bogdan I. Florea, Jacques J. C. Neefjes, Herman S. Overkleeft, Sander I. van Kasteren
Publicado en: Journal of the American Chemical Society, Edición 142/16, 2020, Página(s) 7250-7253, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.9b11969

Fluorogenic Bifunctional trans ‐Cyclooctenes as Efficient Tools for Investigating Click‐to‐Release Kinetics

Autores: Mark A. R. Geus, Elmer Maurits, Alexi J. C. Sarris, Thomas Hansen, Max S. Kloet, Kiki Kamphorst, Wolter Hoeve, Marc S. Robillard, Andrea Pannwitz, Sylvestre A. Bonnet, Jeroen D. C. Codée, Dmitri V. Filippov, Herman S. Overkleeft, Sander I. Kasteren
Publicado en: Chemistry – A European Journal, Edición 26/44, 2020, Página(s) 9900-9904, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201905446

Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

Autores: Michel J. van de Graaff, Timo Oosenbrug, Mikkel H. S. Marqvorsen, Clarissa R. Nascimento, Mark A. R. de Geus, Bénédicte Manoury, Maaike E. Ressing, Sander I. van Kasteren
Publicado en: Bioconjugate Chemistry, Edición 31/6, 2020, Página(s) 1685-1692, ISSN 1043-1802
Editor: American Chemical Society
DOI: 10.1021/acs.bioconjchem.0c00237

Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans -Cyclooctene-Modified Epitopes

Autores: Anouk M. F. van der Gracht, Mark A. R. de Geus, Marcel G. M. Camps, Tracy J. Ruckwardt, Alexi J. C. Sarris, Jessica Bremmers, Elmer Maurits, Joanna B. Pawlak, Michelle M. Posthoorn, Kimberly M. Bonger, Dmitri V. Filippov, Herman S. Overkleeft, Marc S. Robillard, Ferry Ossendorp, Sander I. van Kasteren
Publicado en: ACS Chemical Biology, Edición 13/6, 2018, Página(s) 1569-1576, ISSN 1554-8929
Editor: American Chemical Society
DOI: 10.1021/acschembio.8b00155

Efficient synthesis and enzymatic extension of an N -GlcNAz asparagine building block

Autores: Mikkel Haarslev Schröder Marqvorsen, Sivasinthujah Paramasivam, Ward Doelman, Antony John Fairbanks, Sander Izaäk van Kasteren
Publicado en: Chemical Communications, Edición 55/36, 2019, Página(s) 5287-5290, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/c9cc02051a

Fast and pH‐Independent Elimination of trans ‐Cyclooctene by Using Aminoethyl‐Functionalized Tetrazines

Autores: Alexi J. C. Sarris, Thomas Hansen, Mark A. R. de Geus, Elmer Maurits, Ward Doelman, Herman S. Overkleeft, Jeroen D. C. Codée, Dmitri V. Filippov, Sander I. van Kasteren
Publicado en: Chemistry – A European Journal, Edición 24/68, 2018, Página(s) 18075-18081, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201803839

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