Troy+ stomach stem cells in homeostasis, repair and pathogenesis

Informazioni relative al progetto

Troy Stem Cells

ID dell’accordo di sovvenzione: 639050

DOI 10.3030/639050

Progetto chiuso

Data della firma CE 31 Luglio 2015

Data di avvio 1 Agosto 2015

Data di completamento 31 Luglio 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 570 398,99

Contributo UE € 1 570 398,99

Coordinato da

INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
Austria

Pubblicazioni

Peer reviewed articles (8)

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis

Autori: Tadasuke Tsukiyama, Juqi Zou, Jihoon Kim, Shohei Ogamino, Yuki Shino, Takamasa Masuda, Alessandra Merenda, Masaki Matsumoto, Yoichiro Fujioka, Tomonori Hirose, Sayuri Terai, Hidehisa Takahashi, Tohru Ishitani, Keiichi I. Nakayama, Yusuke Ohba, Bon-Kyoung Koo, Shigetsugu Hatakeyama
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-18257-3

Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations

Autori: Therese Seidlitz, Yi-Ting Chen, Heike Uhlemann, Sebastian Schölch, Susan Kochall, Sebastian R. Merker, Anna Klimova, Alexander Hennig, Christine Schweitzer, Kristin Pape, Gustavo B. Baretton, Thilo Welsch, Daniela E. Aust, Jürgen Weitz, Bon-Kyoung Koo, Daniel E. Stange
Pubblicato in: Gastroenterology, Numero 157/6, 2019, Pagina/e 1599-1614.e2, ISSN 0016-5085
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2019.09.026

Human organoids: model systems for human biology and medicine

Autori: Jihoon Kim, Bon-Kyoung Koo, Juergen A. Knoblich
Pubblicato in: Nature Reviews Molecular Cell Biology, Numero 21/10, 2020, Pagina/e 571-584, ISSN 1471-0072
Editore: Nature Publishing Group
DOI: 10.1038/s41580-020-0259-3

Stem Cells in Repair of Gastrointestinal Epithelia

Autori: Amanda Andersson-Rolf, Matthias Zilbauer, Bon-Kyoung Koo, Hans Clevers
Pubblicato in: Physiology, Numero 32/4, 2017, Pagina/e 278-289, ISSN 1548-9213
Editore: American Physiological Society
DOI: 10.1152/physiol.00005.2017

Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer

Autori: Maureen Spit, Bon-Kyoung Koo, Madelon M. Maurice
Pubblicato in: Open Biology, Numero 8/9, 2018, Pagina/e 180120, ISSN 2046-2441
Editore: Royal Society Publishing
DOI: 10.1098/rsob.180120

Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology

Autori: Jihoon Kim, Bon-Kyoung Koo, Ki-Jun Yoon
Pubblicato in: Viruses, Numero 11/2, 2019, Pagina/e 124, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11020124

Human gastric cancer modelling using organoids

Autori: Therese Seidlitz, Sebastian R Merker, Alexander Rothe, Falk Zakrzewski, Cläre von Neubeck, Konrad Grützmann, Ulrich Sommer, Christine Schweitzer, Sebastian Schölch, Heike Uhlemann, Anne-Marlene Gaebler, Kristin Werner, Mechthild Krause, Gustavo B Baretton, Thilo Welsch, Bon-Kyoung Koo, Daniela E Aust, Barbara Klink, Jürgen Weitz, Daniel E Stange
Pubblicato in: Gut, Numero 68/2, 2019, Pagina/e 207-217, ISSN 0017-5749
Editore: BMJ Publishing Group
DOI: 10.1136/gutjnl-2017-314549

Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells

Autori: Seungmin Han, Juergen Fink, David J. Jörg, Eunmin Lee, Min Kyu Yum, Lemonia Chatzeli, Sebastian R. Merker, Manon Josserand, Teodora Trendafilova, Amanda Andersson-Rolf, Catherine Dabrowska, Hyunki Kim, Ronald Naumann, Ji-Hyun Lee, Nobuo Sasaki, Richard Lester Mort, Onur Basak, Hans Clevers, Daniel E. Stange, Anna Philpott, Jong Kyoung Kim, Benjamin D. Simons, Bon-Kyoung Koo
Pubblicato in: Cell Stem Cell, Numero 25/3, 2019, Pagina/e 342-356.e7, ISSN 1934-5909
Editore: Cell Press
DOI: 10.1016/j.stem.2019.07.008

Non-peer reviewed articles (1)

Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging

Autori: Szu-Hsien (Sam) Wu, Ji-Hyun Lee, and Bon-Kyoung Koo
Pubblicato in: Molecules and Cells, 2019, ISSN 0219-1032
Editore: The Korean Society for Molecular and Cellular Biology
DOI: 10.14348/molcells.2019.0006