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The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

Autori: Tobias Rothe, Natacha Ipseiz, Maria Faas, Stefanie Lang, Francesc Perez-Branguli, Daniel Metzger, Hiroshi Ichinose, Beate Winner, Georg Schett, Gerhard Krönke
Pubblicato in: The Journal of Immunology, Numero 198/10, 2017, Pagina/e 3878-3885, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.1600638

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

Autori: Stefan Uderhardt, Jochen A. Ackermann, Tobias Fillep, Victoria J. Hammond, Johann Willeit, Peter Santer, Manuel Mayr, Markus Biburger, Meike Miller, Katie R. Zellner, Konstantin Stark, Alexander Zarbock, Jan Rossaint, Irene Schubert, Dirk Mielenz, Barbara Dietel, Dorette Raaz-Schrauder, Cihan Ay, Thomas Gremmel, Johannes Thaler, Christian Heim, Martin Herrmann, Peter W. Collins, Gernot Schabbauer,
Pubblicato in: The Journal of Experimental Medicine, Numero 214/7, 2017, Pagina/e 2121-2138, ISSN 0022-1007
Editore: Rockefeller University Press
DOI: 10.1084/jem.20161070

Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease

Autori: René Pfeifle, Tobias Rothe, Natacha Ipseiz, Hans U Scherer, Stephan Culemann, Ulrike Harre, Jochen A Ackermann, Martina Seefried, Arnd Kleyer, Stefan Uderhardt, Benjamin Haugg, Axel J Hueber, Patrick Daum, Gordon F Heidkamp, Changrong Ge, Sybille Böhm, Anja Lux, Wolfgang Schuh, Iryna Magorivska, Kutty S Nandakumar, Erik Lönnblom, Christoph Becker, Diana Dudziak, Manfred Wuhrer, Yoann Rombouts,
Pubblicato in: Nature Immunology, 2016, ISSN 1529-2908
Editore: Nature Publishing Group
DOI: 10.1038/ni.3579

Locally renewing resident synovial macrophages provide a protective barrier for the joint

Autori: Stephan Culemann, Anika Grüneboom, José Ángel Nicolás-Ávila, Daniela Weidner, Katrin Franziska Lämmle, Tobias Rothe, Juan A. Quintana, Philipp Kirchner, Branislav Krljanac, Martin Eberhardt, Fulvia Ferrazzi, Elke Kretzschmar, Martin Schicht, Kim Fischer, Kolja Gelse, Maria Faas, René Pfeifle, Jochen A. Ackermann, Milena Pachowsky, Nina Renner, David Simon, Reiner F. Haseloff, Arif B. Ekici,
Pubblicato in: Nature, Numero 572/7771, 2019, Pagina/e 670-675, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-019-1471-1

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