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Pubblicazioni

Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma

Autori: Richard Mair, Alan J. Wright, Susana Ros, De-en Hu, Tom Booth, Felix Kreis, Jyotsna Rao, Colin Watts, Kevin M. Brindle
Pubblicato in: Cancer Research, Numero 78/18, 2018, Pagina/e 5408-5418, ISSN 0008-5472
Editore: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-18-0759

Photogenerated Radical in Phenylglyoxylic Acid for in Vivo Hyperpolarized 13 C MR with Photosensitive Metabolic Substrates

Autori: Irene Marco-Rius, Tian Cheng, Adam P. Gaunt, Saket Patel, Felix Kreis, Andrea Capozzi, Alan J. Wright, Kevin M. Brindle, Olivier Ouari, Arnaud Comment
Pubblicato in: Journal of the American Chemical Society, Numero 140/43, 2018, Pagina/e 14455-14463, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.8b09326

Dynamic 1 H imaging of hyperpolarized [1- 13 C]lactate in vivo using a reverse INEPT experiment

Autori: Jiazheng Wang, Felix Kreis, Alan J. Wright, Richard L. Hesketh, Malcolm H. Levitt, Kevin M. Brindle
Pubblicato in: Magnetic Resonance in Medicine, Numero 79/2, 2018, Pagina/e 741-747, ISSN 0740-3194
Editore: John Wiley & Sons Inc.
DOI: 10.1002/mrm.26725

Glyoxalase activity in human erythrocytes and mouse lymphoma, liver and brain probed with hyperpolarized 13C-methylglyoxal

Autori: Dmitry Shishmarev, Philip W. Kuchel, Guilhem Pagès, Alan J. Wright, Richard L. Hesketh, Felix Kreis, Kevin M. Brindle
Pubblicato in: Communications Biology, Numero 1/1, 2018, ISSN 2399-3642
Editore: Nature Research
DOI: 10.1038/s42003-018-0241-1

Liquid-state carbon-13 hyperpolarization generated in an MRI system for fast imaging

Autori: A. B. Schmidt, S. Berner, W. Schimpf, C. Müller, T. Lickert, N. Schwaderlapp, S. Knecht, J. G. Skinner, A. Dost, P. Rovedo, J. Hennig, D. von Elverfeldt, J. -B. Hövener
Pubblicato in: Nature Communications, Numero 8, 2017, Pagina/e 14535, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/ncomms14535

Heteronuclear 1D and 2D NMR Resonances Detected by Chemical Exchange Saturation Transfer to Water

Autori: Ricardo P. Martinho, Mihajlo Novakovic, Gregory L. Olsen, Lucio Frydman
Pubblicato in: Angewandte Chemie International Edition, Numero 56/13, 2017, Pagina/e 3521-3525, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201611733

Relaxation-Assisted Separation of Overlapping Patterns in Ultra-Wideline NMR Spectra

Autori: Michael J. Jaroszewicz, Lucio Frydman, Robert W. Schurko
Pubblicato in: The Journal of Physical Chemistry A, Numero 121/1, 2016, Pagina/e 51-65, ISSN 1089-5639
Editore: American Chemical Society
DOI: 10.1021/acs.jpca.6b10007

Metabolic and Molecular Imaging with Hyperpolarised Tracers

Autori: Jason Graham Skinner, Luca Menichetti, Alessandra Flori, Anna Dost, Andreas Benjamin Schmidt, Markus Plaumann, Ferdia Aiden Gallagher, Jan-Bernd Hövener
Pubblicato in: Molecular Imaging and Biology, Numero 20/6, 2018, Pagina/e 902-918, ISSN 1536-1632
Editore: Elsevier BV
DOI: 10.1007/s11307-018-1265-0

Efficient Hyperpolarization of U- 13 C-Glucose Using Narrow-Line UV-Generated Labile Free Radicals

Autori: Andrea Capozzi, Saket Patel, Christine Pepke Gunnarsson, Irene Marco-Rius, Arnaud Comment, Magnus Karlsson, Mathilde H. Lerche, Olivier Ouari, Jan Henrik Ardenkjaer-Larsen
Pubblicato in: Angewandte Chemie International Edition, Numero 58/5, 2019, Pagina/e 1334-1339, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201810522

A framework for tracer-based metabolism in mammalian cells by NMR

Autori: Raquel Saborano, Zuhal Eraslan, Jennie Roberts, Farhat L. Khanim, Patricia F. Lalor, Michelle A. C. Reed, Ulrich L. Günther
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-37525-3

SABRE-Relay: A Versatile Route to Hyperpolarization

Autori: Soumya S. Roy, Kate M. Appleby, Elizabeth J. Fear, Simon B. Duckett
Pubblicato in: The Journal of Physical Chemistry Letters, Numero 9/5, 2018, Pagina/e 1112-1117, ISSN 1948-7185
Editore: American Chemical Society
DOI: 10.1021/acs.jpclett.7b03026

Optimized microwave delivery in dDNP

Autori: Mohammed M. Albannay, Joachim M.O. Vinther, Andrea Capozzi, Vitaliy Zhurbenko, Jan Henrik Ardenkjaer-Larsen
Pubblicato in: Journal of Magnetic Resonance, Numero 305, 2019, Pagina/e 58-65, ISSN 1090-7807
Editore: Academic Press
DOI: 10.1016/j.jmr.2019.06.004

Looped-PROjected SpectroscopY (L-PROSY): A simple approach to enhance backbone/sidechain cross-peaks in 1 H NMR

Autori: Mihajlo Novakovic, Samuel F. Cousin, Michael J. Jaroszewicz, Rina Rosenzweig, Lucio Frydman
Pubblicato in: Journal of Magnetic Resonance, Numero 294, 2018, Pagina/e 169-180, ISSN 1090-7807
Editore: Academic Press
DOI: 10.1016/j.jmr.2018.07.010

Extending the Scope of 19 F Hyperpolarization through Signal Amplification by Reversible Exchange in MRI and NMR Spectroscopy

Autori: Alexandra M. Olaru, Thomas B. R. Robertson, Jennifer S. Lewis, Alex Antony, Wissam Iali, Ryan E. Mewis, Simon B. Duckett
Pubblicato in: ChemistryOpen, Numero 7/1, 2018, Pagina/e 97-105, ISSN 2191-1363
Editore: Wiley Online Library
DOI: 10.1002/open.201700166

Compact, low-cost NMR spectrometer and probe for dissolution DNP

Autori: Mohammed M. Albannay, Joachim M.O. Vinther, Jan Raagaard Petersen, Vitaliy Zhurbenko, Jan Henrik Ardenkjaer-Larsen
Pubblicato in: Journal of Magnetic Resonance, Numero 304, 2019, Pagina/e 7-15, ISSN 1090-7807
Editore: Academic Press
DOI: 10.1016/j.jmr.2019.04.016

Sensitivity-enhanced detection of non-labile proton and carbon NMR spectra on water resonances

Autori: Mihajlo Novakovic, Ricardo P. Martinho, Gregory L. Olsen, Michael S. Lustig, Lucio Frydman
Pubblicato in: Physical Chemistry Chemical Physics, Numero 20/1, 2018, Pagina/e 56-62, ISSN 1463-9076
Editore: Royal Society of Chemistry
DOI: 10.1039/c7cp07046b

PIN diode driver for NMR and MRI

Autori: D.H. Johansen, M.M. Albannay, J.R. Petersen, V. Zhurbenko, J.H. Ardenkjær-Larsen
Pubblicato in: Journal of Magnetic Resonance, Numero 300, 2019, Pagina/e 114-119, ISSN 1090-7807
Editore: Academic Press
DOI: 10.1016/j.jmr.2019.01.017

Design of a local quasi-distributed tuning and matching circuit for dissolution DNP cross polarization

Autori: Joachim M.O. Vinther, Vitaliy Zhurbenko, Mohammed M. Albannay, Jan Henrik Ardenkjær-Larsen
Pubblicato in: Solid State Nuclear Magnetic Resonance, Numero 102, 2019, Pagina/e 12-20, ISSN 0926-2040
Editore: Academic Press
DOI: 10.1016/j.ssnmr.2019.04.006

Mechanistic insight into novel sulfoxide containing SABRE polarisation transfer catalysts

Autori: Ben. J. Tickner, Jennifer S. Lewis, Richard O. John, Adrian C. Whitwood, Simon B. Duckett
Pubblicato in: Dalton Transactions, Numero 48/40, 2019, Pagina/e 15198-15206, ISSN 1477-9226
Editore: Royal Society of Chemistry
DOI: 10.1039/c9dt02951f

Unprecedented Carbon Signal Enhancement in Liquid-State NMR Spectroscopy

Autori: György Pintér, Harald Schwalbe
Pubblicato in: Angewandte Chemie International Edition, Numero 56/29, 2017, Pagina/e 8332-8334, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201702766

Optimal Destabilization of DNA Double Strands by Single-Nucleobase Caging

Autori: Patrick Seyfried, Marcel Heinz, György Pintér, Dean-Paulos Klötzner, Yvonne Becker, Michael Bolte, Hendrik R. A. Jonker, Lukas S. Stelzl, Gerhard Hummer, Harald Schwalbe, Alexander Heckel
Pubblicato in: Chemistry - A European Journal, Numero 24/66, 2018, Pagina/e 17568-17576, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201804040

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